Study links polycystic ovary syndrome with early vascular changes of heart disease
...ing that women with PCOS "are at greatest risk for diabetes and coronary artery disease." Dr. Talbott's study involved 61 women with PCOS who underwent noninvasive electron beam tomography scanning of their coronary and abdominal arteries. Results for the 61 women with PCOS were compared with those for co...Genetic variant linked to weakened heart pumping
...diabetes," Donahue said. "Additionally, gender and diabetes were also independently associated with ejection f...ber was pumped out, Donahue said. Patients without diabetes in the study had an average ejection fraction of 53, compared to 50 for those with one allele and 42...U. Va. Health System to develop new approaches to treat type 1 diabetics with islet cell transplants
...ffective and more applicable to people with type 1 diabetes in this country and worldwide, " said Dr. Jerry Na...en and Nadler discovered that lisofylline prevents diabetes from coming back after islet cells are transplanted into diabetic mice. "Lisofylline shows some bene...JCI table of contents, November 15 2004
...****** Aging affects susceptibility to type 2 diabetes Earlier research has reported a sm... in the skeletal muscle of individuals with type 2 diabetes mellitus (T2DM) and in first degree relatives who do not have diabetes. However it was previously un...Aging affects susceptibility to type 2 diabetes
... in the skeletal muscle of individuals with type 2 diabetes mellitus (T2DM) and in first degree relatives who do not have diabetes. However it was previously unknown whether this was an inherited genetic defect or the result of environmental triggers. T2DM is caused by the development of insulin resistance in...Army-funded effort examines androgen's role in bone loss
...., associate professor of medicine (endocrinology, diabetes and clinical nutrition) and behavioral neuroscience, OHSU School of Medicine, and research biologist, Portland Veterans Affairs Medical Center. "The goal of the Army in funding this grant is to identify factors that promote a healthy skeleton, tha...Scientists generate human islet precursor cells in culture
...beta cell and may eventually have applications for diabetes treatment. The study appears on-line today in Sci...vels fall causing blood glucose levels to rise and diabetes results. This study's findings may eventually have implications for islet transplantation, an exper...Racial disparities noted in immune system genes
...e a fundamental component of heart attack, stroke, diabetes and kidney disease, all of which strike African Americans in higher proportions than whites. Other disorders associated with the inflammatory response include premature labor, transplant rejection and autoimmune disorders such as multiple sclerosis a...JCI table of contents, December 1 2004
... triglyceride production and utilization in type 2 diabetes TITLE: GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization AUTHOR CONTACT: Barbara B. Kahn Beth Israel Deaconess Medical Center Boston, Massachusetts, USA Phone: 617-667-5422 Fax: 617-667-2927 E-m...Exercise doesn't work for us all
...ining on insulin sensitivity- a marker of risk for diabetes and heart disease- also varied. It improved in 58 per cent of the volunteers following exercise, but in 42 per cent it showed no improvement or, in a few cases, may have got worse. "It's negative, but it's true. Some people slog away and don't get an...Carnegie Mellon scientist develops way to deliver promising genetic tool into living cells
...lar events that lead to diseases such as cancer or diabetes in animal models. Ly is currently extending his research to show that GPNAs are absorbed throughout the body in mice that receive these agents....JCI table of contents, December 15 2004
Oxidants link obesity to diabetes Individuals with the metabolic syndrome are at ri...etic neuropathy. TITLE: Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily AUTHOR CONTACT: Angelika Bierhaus Unive...VA patients get better chronic, preventive care than similar US adults
...2 percent in the national sample. Similarly, for diabetes care, the VA sample fared much better--70 percent of indicated care was delivered compared with 57 percent in the national sample. There were a few conditions where there was little difference between the two samples. For example, 73 percent of indi...Federal/private partners launch resource for diabetic kidney disease gene studies
...ical data, from more than 1,700 adults with type 1 diabetes in the United States and Canada. Of those, 818 have had diabetes at least 10 years and have developed kidney disease, a common complication of diabetes. The other 89...No blind mice, thanks to UF scientists
... known as SDF-1 and retinopathy, a complication of diabetes and the leading cause of blindness in working-age ...od pressure and blood sugar levels associated with diabetes cause leaks in blood vessels within the eye and hinder the flow of essential chemicals. The eye comp...Development of portable infectious disease detector
...nage their disease in a way that is similar to how diabetes patients can monitor their condition since the introduction of home blood glucose detectors." The collaboration's goal is to produce its first portable HIV monitor within two years. In addition to such "point of care" devices, Wikswo and Pyle are joi...High sugar levels increase cancer and mortality risk
Elevated blood sugar levels and diabetes are risk factors for developing several types of c...rticipants with diabetes, as well as those without diabetes and higher fasting blood sugar levels, were more likely to develop cancer or to die from cancer. For...UCLA/VA researchers discover fat gene
...ide a new target for therapies to control obesity, diabetes and other weight-related disorders. The first issue of the new journal Cell Metabolism publishes the findings in its January 2005 edition. "Lipin regulates how the body stores and burns fat. Our findings suggest that differences in lipin levels may...Fat hormone acts on brain circuit to curb obesity, diabetes
...sight into potential mechanisms underlying type II diabetes and suggest new avenues for treatment, according t...ormonal function. "As the incidence of obesity and diabetes continues to rise in industrialized countries, a clear understanding of the cellular and neuroanatom...Jeans too tight? 50 percent of adults can blame their genes and not just diet and exercise
...me from being obese. The risk of heart disease and diabetes increases as person becomes increasingly overweight. 'Risk factors' seem to become a neutral term but they're not at all neutral. They can be a death sentence."...