Lewis C. Cantley, Ph.D., receives Pezcoller-AACR International Award for Cancer Research
...currently exploring the role of PI3K in cancer and diabetes through the development of mouse models in which genes for enzymes in this pathway are altered. Says Cantley, "I'm honored to have received this award, indicating an international recognition of the importance of PI 3-kinase in human cancer. Over th...Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis
...r evaluation to hepatologists. Obesity and type-2 diabetes are associated to NASH. Since the prevalence of these diseases is increasing, the prevalence of NASH is also expected to increase and therefore, this disease has become an emerging public issue in United States as well as in other developed countries...'Motherwell's babies' study may yield up clues for adult diseases
... all factors which can predispose an individual to diabetes and coronary heart disease. Dr Rebecca Reynolds of...dulthood, particularly the risks of heart disease, diabetes and osteoporosis. If the mother eats an unbalanced diet this can trigger her body to produce increas...Research news from the Friedman School of Nutrition Science and Policy at Tufts University
...syndrome, puts people at increased risk of type II diabetes and heart disease. Overweight students were nearly three times more likely to exhibit a component of the metabolic syndrome than students of normal weight. Overweight students had higher hip and waist circumferences, higher blood pressure, higher i...Mouse with designer liver has enhanced glucose tolerance and improved insulin response
...r understanding better the pathogenesis of type II diabetes and designing anti-diabetes drugs." Co-authors on this study from Dr. Feng's laboratory were Emilie Bard-Chapeau, Ph.D., and Shinong Long, Ph.D., postdoctoral fellows, and Eric Zhang, graduate student in the Burnham Institute-UCSD's joint graduate tr...Jeffrey Friedman, discoverer of leptin, receives Gairdner, Passano awards
...levels, including several different forms of human diabetes and a condition known as hypothalamic amennorhea. This condition, which develops in extremely thin women -- often ballet dancers or long-distance runners -- is one of the most common causes of infertility in women, and leptin treatment restored repro...Breakthrough in stem cell research
...lso forms the gut and liver are the holy grail for diabetes researchers," said Dr Sidhu. "That's because they are destroyed in type-1 diabetes, which affects at least 100,000 people in Australia. So far there is no cure for it. "Human embryonic stem cell research offers a permanent answer to the problem. It ...Gene regions beyond protein instructions important in disease
...etics mimics that of more common diseases, such as diabetes and heart disease. "It's a funny mutation in a fu...gions of a gene," he continues. "For diseases like diabetes and heart disease, just as for Hirschsprung disease, multiple inherited factors contribute to the di...University of Pittsburgh gets wired for speed with Apple Xserve G5 cluster
...idemiology of common yet complex disorders such as diabetes and inflammatory bowel disease. "In a sense, we're gene hunters." Dr. Barmada and his colleagues are using their new computing power dubbed locally as the Gattaca Cluster for the 1997 feature film to analyze data involving the many genes that lead ...JCI table of contents May 1, 2005
...f how vascular calcification arises in response to diabetes and a high fat diet. TITLE: Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals AUTHOR CONTACT: Dwight Towler Washington University School of Medicine, St. Louis, MO USA Phone: 314-454-7434; Fax: 314-454-8434; E-mail: dt...PNAS highlights for the week of April 18 - 22
...ress hormone related to conditions such as type II diabetes and hypertension. Happier individuals also showed lower responses to stress in plasma fibrinogen levels, a protein that in high concentrations often signals future problems with coronary heart disease. Finally, happy men had lower heart rates over th...Scientists propose new method for studying ion channel kinetics
... to cause severe diseases like cystic fibrosis and diabetes and more subtle, but still dangerous physiological effects, like over-responses to general anesthetics. According to Bruno, "we found a new way of simplifying the models that reflects the fact that one's knowledge is incomplete about what transitions...Faulty body clock leads to obesity and diabetes
EVANSTON, Ill. --- Obesity and diabetes in both adults and children are rising at alarming...imately 18 million people in the United State have diabetes and nearly two-thirds of adults are overweight, which includes 30 percent who are obese. Together, d...Report suggests infectious connection to chronic diseases
...hronic illnesses be developed. "Atherosclerosis, diabetes and Alzheimer's disease are all devastating chronic illnesses that cost millions of dollars in healthcare every year and exact incalculable tolls of pain and suffering. Each of these diseases was once thought to be caused exclusively by environmenta...Stem cells from brain transformed to produce insulin at Stanford
...ls in people with diabetes. Right now, people with diabetes face a lifetime of insulin injections. In rare cases, some patients can receive cell transplants from cadavers, but that source of cells is far smaller than the total number of people who could benefit....Natural glucose byproduct may prevent brain damage and cognitive impairment after diabetic coma
...hat serves as the body's primary fuel. People with diabetes lack the ability to make insulin, the primary enzy...mated that between 2 and 15 percent of people with diabetes will have at least one episode of diabetic coma resulting from severe hypoglycemia," says Swanson, c...Nano-particle research will benefit inhaler-users
...suffering from conditions as diverse as asthma and diabetes could benefit from research at Cardiff University to improve the effectiveness of drugs taken through spray inhalers. Scientists in the Welsh School of Pharmacy are working on new nano-particle drug formulations for inhalers, and enhancers to improve...JCI table of contents May 2, 2005
...of hepatic glucose production Patients with type 2 diabetes show insulin resistance in the muscle, fat, and liver. Mice with mutations in the insulin receptor (Insr) have been used to study insulin resistance previously. In a new study appearing in the May 2 print issue of The Journal of Clinical Investigati...JCI table of contents June 1, 2005
...K FGF-21 finds itself as a new therapy for type 2 diabetes Members of the fibroblast growth factor (FGF) family of proteins play many regulatory roles in several tissues. FGF-21 is a novel member of the FGF family, but its biological role was not known. In a study appearing online on May 2 in advance of th......ts can cut risk factors for heart disease, stroke, diabetes or other serious illnesses. An $8 million, five-year botanical research grant from the National Institutes of Health (NIH) will enable Rutgers plant scientists to collaborate with Pennington researchers in forming the NIH Center for Botanicals and Me...