APS oxytocin/vasopressin conference: 13 highlighted presentations
...velopment. "Amelioration of fetal alcohol-induced diabetes insipidus by dietary choline during pregnancy in the rat." John Claybaugh, Ginger Pole, Aileen Sato, Danielle Bird, Catherine Uyehara, Tripler Army Medical Center, Honolulu. Funded in part by Hawaii Community Foundation and Clinical Research Center...Choline during pregnancy may avoid, reverse some Fetal Alcohol Syndrome nervous disorders
... the brain and store less in the pituitary." Could diabetes insipidus-like symptoms lead to FAS test? With ins... normal. These are some of the classic symptoms of diabetes insipidus, a disease that also affects humans. Claybaugh's team found that stimuli which normally pr...Study reveals trigger for insulin resistance in liver, potential drug targets
...condition that increases the chances of developing diabetes and heart disease. The team's findings also identify a potential target for drugs to prevent or treat the condition, the researchers said. The livers of mice lacking an enzyme called mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 (m...Insulin pulses keep the liver lean
...ilure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The current stu...ulting hikes in blood sugar and fat can also spell diabetes and heart disease, Najjar added. "When we eat, the pancreas produces insulin, which stimulates the a...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...s by approximately 20% in the db/db mouse model of diabetes without affecting insulin levels. This compares f...litazone, a widely-prescribed treatment for type 2 diabetes that acts by sensitizing cells to insulin. Additional presentation of these data will be made in Oc...Researchers identify new genes that regulate aging
...nding human genes could potentially play a role in diabetes and cancer, according to senior author Cynthia Kenyon, of the University of California, San Francisco, and her coauthors....Diabetic nerve therapy shows 'striking' results
...ch into a new treatment for nerve damage caused by diabetes could bring relief to millions of diabetic patient...neration are borne out long-term. Nerve disease in diabetes is the major cause of non-traumatic lower limb amputations in Europe and North America. Scientists a...JCI Table of contents August 1, 2005
...l molecules which mediate susceptibility to type I diabetes in man (DQ 8) and in the NOD mouse (I-Ag7) have similar function and sequence specificity. The authors show that when they simply elute from purified DQ8 or I-Ag7 molecules isolated from transfected cells, the peptide epitopes are different from thos...VIB signs cooperation agreement for the development of a new, universal flu vaccine
...vises flu vaccination for those over 60 years old, diabetes patients, people with diminished resistance or chronic kidney, heart and lung disorders. However, everyone can consider vaccination: it will give you 80% less chance of getting the flu next winter. No more annual renewal thanks to new research? VI...Joslin researchers discover new gene for type 2 diabetes using DNA chips
...ts (beta cells) from all of the people with type 2 diabetes studied demonstrated a marked down-regulation of t...he pathogenesis of the most common forms of type 2 diabetes and a possible new target for treatment of this disease," he said. The investigators, including lea...Type 2 diabetes: Problems in the furnace
...ctable as early as 20 years before the symptoms of diabetes become evident. In fact, insulin resistance is now seen as the best predictor that type 2 diabetes will eventually develop, said the study's senior author, Gerald I. Shulman, a Howard Hughes Medical ...New insights into the early development of diabetes and the link to obesity
...n recent years. Virtually all patients with type 2 diabetes have IR, which usually appears some 10V20 years be...se itself. Although the link between IR and type 2 diabetes is well recognized, how IR develops and why it leads to diabetes is not well understood. A study by ...Leptin-signaling protein maintains normal body weight and energy balance in mice
...l collaborator to screen patients with obesity and diabetes for potential mutations in the human SH2-B gene....Life-extending protein keeps blood sugar in check
...ight improve insulin response in those with type 2 diabetes without causing other problems." Pancreatic b cell...ilure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The researchers found that Sirt1 is present in pancreas cells tha...U of M researchers show that increasing sugar processing in the liver can lower blood sugar
...e that concentration could provide a treatment for diabetes and obesity. The research will be published in the Aug. 16 issue of Cell Metabolism. The liver plays an important role in both type 1 and type 2 diabetes. In diabetic patients, the liver makes too much glucose, and muscles and fat are unable to take...HSPH's Walter Willett wins Bristol-Myers Squibb/Mead Johnson Freedom to Discover Award
...percent of strokes, more than 90 percent of type 2 diabetes and more than 70 percent of colon cancer cases cou...nships between what we eat and the risk of cancer, diabetes and cardiovascular disease. Today, these three large-scale cohort studies represent the only such l...Energy management in cells may hold key to cancer defense
... combating cancerous tumor growth, but also type 2 diabetes and obesity. The study, published in the August 1...tempting target for the treatment of some forms of diabetes and even obesity," said Witters. As Witters' laboratory continues to zero in on the central role of ...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...STON - A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiven...e of the Journal of Clinical Investigation. Type 1 diabetes is an autoimmune disease in which the body's immune system mistakenly attacks its own insulin-produc...JCI table of contents September 1, 2005
...major problem for understanding and treating type1 diabetes is that we are unable to directly, but non-invasiv...tigation , Diane Mathis and colleagues from Joslin diabetes Center describe a novel magnetic resonance imaging (MRI) strategy to non-invasively monitor autoimmu......major problem for understanding and treating type1 diabetes is that we are unable to directly, but non-invasiv...stigation, Diane Mathis and colleagues from Joslin diabetes Center describe a novel magnetic resonance imaging (MRI) strategy to non-invasively monitor autoimmu...