Tag: "differentiation" at biology news
Most promising clinical uses for stem cells from fat agreed on by international society
...ations some that are capable of proliferation and differentiation
and other groups consisting of mature cells. The society aims to develop common scientific methods in order to best compare results between studies, and believes that much of the research effort should be directed toward identifying the protein marke...
Researchers provide road map for generating B cells from stem cells
... stem cells, HSCs have already taken some steps in differentiation
and are committed to producing various types of bl...odel system," Singh said. "We know more about the differentiation
of B cells and red cells than other cell types in the blood system." After a series of experiments t...
Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...four genes, three of which are related to cellular differentiation
(a-2u-globulin, VDUP1 and H19) and the fourth of w...ts implication in changes on the state of cellular differentiation
induced by dietary lipids in breast cancer tumours and the degree of malignity of the cancer. In...
Retinal stem cells can regenerate after transplant
...when all the nutrients and signals they needed for differentiation
were still there," says lead author Brenda Coles, a U of T laboratory technician working under the supervision of Professor Derek van der Kooy in the Department of Medical Genetics and Microbiology. "When their eyes fully developed, the human cells s...
Immune system in a bottle could help prevent flu vaccine shortage
...pens inside us. This is particularly important for differentiation
of stem cells into different lineages of immune ce...nverted colloidal crystal scaffold could stimulate differentiation
of human stem cells from blood of adults to functional T and B cells. T and B cells help target and ...
Scientists uncover secret to sharp teeth
...molecular signals regulating asymmetric ameloblast differentiation
from the underlying dental epithelium are not well...istatin allows BMP signals to stimulate ameloblast differentiation
on the labial side of the incisor....
Seeking better cancer treatments
...the male sex steroids and regulates genes for male differentiation
and development. The lengthy and meticulous research began in 1998 with E! 1948 SASTEREC. Structural evidence was found for fine-tuning ligand specificity in the binding domain of the human androgen receptor. This project identified and categorised ...
Finding could improve safety of stem cell transplants
...be." "This is another approach to controlling differentiation
and getting the cell types that you want," says Dr. Brian G. Condie, developmental neurobiologist at UGA and MCG and senior author on the paper. While it's the ability of embryonic stem cells to make all types of tissue from brain cells to hear...
Study in Royal Society journal on possible genetic factors in social responsiblity
...etected events in its host's history, like cryptic differentiation
and refuge zones. Contact: Dr Caroline Nieberding, Unit de recherches zoogographiques, Universit de Lige, Institut de Zoologie, LIGE, 4020, Belgium Proceedings of The Royal Society A: Mathematical, Physical and Engineering Sciences Exact t...
JCI table of contents, December 1 2004
...in contrast to others that have claimed successful differentiation
of BM-SP stem cells in specific tissues. Dr. Cossu...CD40-mediated c-Rel activation and B cell terminal differentiation
AUTHOR CONTACT: Ashish Jain National Institute of Allergy and Infectious Diseases Bethesda, Maryland...
JCI table of contents, December 15 2004
.... TITLE: A crucial role of caspase-3 in osteogenic differentiation
of bone marrow stromal stem cells AUTHOR CONTACT: ...on an intracellular adaptor protein called myeloid differentiation
factor 88 (MyD88). Acquired immunity is a form of cellular defense where foreign substances are atta...
Leibniz prizewinners 2005
...cess in isolating genes which determine the sexual differentiation
of plants. This work is of great importance, not only for basic molecular research, but also for plant breeding as a whole. Through his many years of involvement in the Central Commission for Biosafety (Zentrale Kommission fr die Biologische Sicherhe...
Scientist discover the cellular roots of graying hair
...tors say, appears to be implicated in the mistaken differentiation
of melanocyte stem cells that accompanies the stem cells' depletion. MITF, they conclude, seems to play a crucial role in maintaining the supply of stem cells within the hair follicle, and graying is the result of "incomplete maintenance of melanocyt...
Vollum Institute discovery may unlock human genome
...s examining a transcription factor involved in the differentiation
of dopamine-producing cells. By identifying the targets of the transcription factor, stem cells differentiated as dopamine cells could be developed to treat Parkinson's disease. And a project with Markus Grompe, M.D., of the OHSU Oregon Stem Cell Cen...
Fox Chase Cancer Center scientists discover key proteins linked to aging and cancer
... but are eventually arrested, either through final differentiation
or senescence. Differentiation is the process whe...ntly, the failure of cells to stop growing through differentiation
or senescence can lead to the uncontrolled growth of cancer," Adams emphasized. Both senescence and...
Study examines relationship of vitamin A pathway to breast tumor progression
...of the retinoic acid receptor (RAR), which induces differentiation
of adult epithelial cells. One of the characterist...ch a reduction in function would lead to a loss of differentiation
and tumor progression. To determine whether there is a link between retinol storage, RAR activation,...
EB and IUPS - Where cures of tomorrow can be seen in the science of today
...lectures, and workshops include topics such as the differentiation
of stem cells; mechanisms of neuronal cell death; innate immunity at the epithelial barrier; environmental toxicology; new developments in inflammation; the pathobiology of neoplasia as a gateway to improved prognosis; the pathogenesis of Alzheimer's...
Priming embryonic stem cells to fulfill their promise
...cell types found in the body. Embryonic stem cell differentiation
is complex and far from fully understood. Scientis...rnal inputs known to be involved in triggering the differentiation
of stem cells: soluble growth factors, adjacent cells, mechanical forces, and extracellular matrix p...
Current human embryonic stem cell lines contaminated UCSD/Salk team finds
... many of the specialized media used for growth and differentiation
still contain materials from animal sources and are hence contaminated with Neu5Gc. In addition to using human serum, the researchers suggested the possibility of using what are called "feeder cells" from mice with a human-like defect in Neu5Gc pro...
Researchers find local environment directly influences adult stem cell reservoirs
...coming any other kind of cell. Genes controlling differentiation
are turned off in some stem cell daughters but turned on in others, which move too far away to be influenced. Thus they develop into the egg and nurse cells. The success of this cell-to-cell communication is crucial. When the signals from the stromal...
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