New insights into how Huntington's disease attacks the brain
...ed little signs of the disease. "This is the first direct genetic evidence to demonstrate that abnormal interactions between cells can significantly contribute to brain cell death in a living mouse model of Huntington's disease," said Yang. Yang's team is now trying to pinpoint which of the neighboring ce...Biologists determine genetic blueprint of social amoeba
... in the two cell types," says Kuspa. "You can make direct analogies, or you could learn general principles about how cells regulate their behavior. Both things will apply in the studies we do." He and the other members of the international sequencing team found that there are more protein coding genes in th...New NSF-AAAS report highlights 'learning communities,' other STEM educational strategies
...ven large classes seem intimate as student-leaders direct workshops; creative faculty-development methods; case study-based learning; web-based tools; virtual laboratories; visualization methods; and more. In addition to Ron Ulseth's program in Minnesota, some specific innovative U.S. undergraduate educati...... activating the production of HOW. HOW then takes direct action against Cdc25 RNA by breaking it apart, leading to the arrest of cell division during mesoderm invagination. When Volk and her team studied the newly-formed embryos of mutant fruit flies that lacked the gene for HOW, they found the timing for...ESA's Epidemio and Respond assist during Angolan Marburg outbreak
...supplying satellite-based geo-information products direct to humanitarian users in the field, with partners including UNOSAT, an in-sector service provider within the United Nations community as well as the German Aerospace Centre (DLR). Respond has been established as part of the pilot services of Global ...Newly identified enzyme group converts protein into cellular traffic signal
...w group of enzymes that may help uncover how cells direct internal traffic. The discovery has future implications for conditions -- such as polycystic kidney disease, male infertility, behavioral disorders and cancer -- that involve defects in protein fibers called microtubules. The findings will be publish...Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
...e 600-million-year-old relationship may not be the direct ancestor of the 400-million-year-old relationship," Xiao said. Fungi and algae in modern lichens can easily marry and divorce, he said. "Given the ease with which the symbiotic relationship is formed, I wouldn't be surprised if the land-based relatio...Size matters: fish genitalia attractiveness vs. predatory escape value
... and natural selection, favoring reduced size, may direct evolution and diversification of genitals," said Layman. The researchers studied female preference and male swimming performance in these two species of mosquitofish. In laboratory experiments, females preferred to spend time with videos of males dis...Galvani to receive Young Investigators' Prize from American Society of Naturalists
...stance allele CCR5-delta 32. Much of this work has direct implications for the potential success of different control policies and for the persistence of disease....Two new retrovirusestransmitted from animalsidentified
...rus STLV-3, and was most likely contracted through direct contact with a primate during hunting. HTLV-4 does not have a known primate counterpart and could have arisen through cross-species transmission from an animal carrying an unknown form of STLV. According to William Switzer who led the CDC laboratory ...PNAS highlights for the week of May 16 - 20
...individual carrying the virus was infected through direct contact with a primate. HTLV-4 does not have a primate counterpart, making its origin less clear. The researchers suggest that HTLV-4 may have arisen through cross-species transmission from an animal carrying a highly divergent form of STLV not previ...Scientists generate patient-specific stem cells, Science study says
...ease, so they will probably not be appropriate for direct use in treating patients. In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. Scientists must also find...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...lices." The new study is believed to be the first direct test for nonlinearity in large-scale physical and biological data for the marine environment. The basic methods for testing for linear and nonlinear signatures were developed by Sugihara over years of studying a variety of complex systems (ecosystems...Gene keeps neural cells on correct developmental path
...t REST uses a different temporary off mechanism to direct neuronal development. "This study shows that there is more than one way to keep a REST-regulated gene repressed," said Michael G. Rosenfeld, an HHMI investigator at University of California, San Diego, who co-authored an accompanying commentary in Ce...Oldest cranial, dental and postcranial fossils of early modern European humans confirmed
...Louis, USA recently conducted the first successful direct dating of the material. Several previous attempts to radiocarbon date the Mladec specimens directly have failed, but in the present attempt by using teeth as dating material reliable results were obtained. The findings are documented in the May 19 ...Detecting biological threats top goal of UH project
...," Willson said. "These reagents should also have direct application to clinical diagnostics." Along with polymerase chain reaction (PCR) primers, the new approach will deliver DNA probes that bind to organisms of interest and carry a highly detectable "label" to signal the presence of the organism. Th...STN Expreses Version 8.0 gives information professionals advance analysis and security capabilities
...es and additions we have made to STN Express are a direct result of customer input," said Christine McCue, Manager, Online Services - STN. "We know information professionals have to be able to present search results in reports and presentations that are easy to assemble and communicate effectively the value...Racehorses, asthmatics, meatpackers may have similar etiology of airway disturbances
...of cytokines," small peptide protein hormones that direct and fine-tune the immune system, in a "profile ass...n chronic and acute conditions, probably the first direct beneficial application will be in the area of heaves, which affects many horses, especially as they ...Tracking a killer: Observing liver invasion by malarial parasites
...s life cycle invasion of the liver - have escaped direct observation until now. In their new study publishe...t et al. used intravital microscopy - which allows direct observation of events in a living animal - to study the discrete steps that facilitate the parasites...Dietary supplement a potential treatment for Canavan disease
...ificantly compromised in CD, and provide the first direct evidence that defective myelin synthesis, resulting from a deficiency of NAA-derived acetate, is involved in the pathogenesis of CD. Further, these results make a strong case for acetate supplementation as a potential therapy for this devastating and...