One step closer to prediction: Baltimore to host international scientific meeting
...ed at fostering and promoting cooperative research directed toward improving the prediction of harmful algal bloom events. From Chesapeake Bay to China, more than 40 scientists will present their latest research on harmful algal blooms during the conference -- the third in a series of international GEOHAB mee...Secrets of the cilia: Kidney disease and blindness share common genetic defect
... for the Cure and Prevention of Birth Defects, who directed the research. "Just as defective cilia in kidney tubules underlie kidney disease, defective cilia in the light-sensitive portion of the eye cause retinitis pigmentosa." For the past 15 years, Hildebrandt and his collaborators have been studying nephr...New slant on vision research: Neurons sensitive to viewing angle
...d Sheng He, associate professor of psychology, who directed the study. "This study supports the idea that we have explicit representations in our brains for specific views of objects." The study was carried out jointly with Fang Fang, a graduate student in He's laboratory. The researchers presented volun...Incubator company at NJIT develops lifesaving MRI coil for small animals
...hai, China. Prior to joining Supertron, DeVries directed a research project supported by Southern California Edison, led a research team at Polytechnic Institute, Brooklyn, worked as a venture capitalist at Pennwood Capital. He holds an MBA from Columbia University and a bachelor's degree in physics from ......e number two contributors to the sequencing effort directed at the X chromosome. It was led by the Wellcome Trust Sanger Institute in Britain. The story of each chromosome will be published eventually, with all the important features explained, said Scherer. "I expect this chromosome is the all-star of the ...Student work in human subjects protection sought for FDA conference at UH
...lenges in Protecting Human Subjects," the theme is directed at exploring the FDA critical pathway for approval of new medical products and will be held at the Hilton UH Hotel and Conference Center. "In order to promote the next generation who will oversee the protection of human subjects in research, we are...Highly adaptable genome in gut bacterium key to intestinal health
...zed' pieces; the utensils are a variety of enzymes directed at different types of carbohydrates." When a set of germ-free mice were fed a simple-sugar diet--instead of a complex-carbohydrate diet--and then inoculated with B. theta, the genome activity analysis showed that B. theta had adaptively switched on a...Protein protects kidneys from damage caused by chronic renal disease and injury
...fessor of pathology in the U-M Medical School, who directed the research study. "But instead of suppressing the signal, KCP enhances it by strengthening interactions between the BMP protein and its receptor on kidney cells." "In two different models of mice with renal injuries, we found that KCP activity was......d metastatic properties, suggest that therapeutics directed against this single target could prove efficacious in controlling the ability of tumors to recruit new blood vessels, grow and spread to distant sites."...Inexpensive treatment stops multi-drug resistant TB in its tracks
...trol multi-drug resistance. Without DOTS, measures directed to multi-drug-resistant TB will not work." The unexpected effectiveness of DOTS in reducing the transmission of multi-drug-resistant TB in the Orizaba region of Mexico underscores the importance of a global strategy for tackling the TB pandemic, sai...New hope for Chagas disease treatment
...ly 10 percent of current global health research is directed to address the medical needs of 90 percent of the human population."...Alcoholism reduces male heart's ability to synthesize protein; possible therapy target?
... Next steps: Vary said: "Future research will be directed at developing potential therapeutic modalities that prevent the alcohol-induced defects in protein synthesis."...Radar tracking reveals that butterflies follow decisive flight paths
...iques. Butterflies were tracked undertaking fast, directed flights to potential feeding sites or interspersing periods of foraging with looping "orientation" flights. Knowing how butterflies navigate can help us understand how capable they are of maintaining sustainable populations in our increasingly fragm...Researchers improve design of genetic on-off switches
...al Academy of Sciences, combines the advantages of directed evolution and computationally driven rational desi...tein-engineering approach used by Zhao's team used directed evolution, which mimics natural evolution in a test tube, to force rapid evolution of human estrogen...Viruses may one day help treat brain tumors
...ga Saeki, associate professor of neurosurgery, who directed the research, and first author Hirokazu Kambara, a post-doctoral fellow. The study began with a laboratory version of a herpes virus that was missing several genes. The virus could infect only malignant glioma cells, but once inside the cells, it re...Worth the wait? A neural mechanism related to impulsive decision-making
...onal, and their actions are not always exclusively directed toward the maximization of gain. A prominent example of such sub-optimal choice behavior is impulsive decision-making, in which case an immediate but disadvantageous reward may be preferred over a delayed but more advantageous reward. In their new wo...Scientists infuse rat spinal cords with brain-derived human stem cells
... in the journal Human Gene Therapy, the scientists directed certain types of neural stem cells to secrete a neuron-protecting protein before injecting them into the rat spinal cord where motor neurons reside. Motor neurons dictate muscle movement by relaying messages from the spinal cord and brain to the rest...Readers of genome decipher signatures of cancer patient outcomes
...l at the time of diagnosis. "Those patients can be directed toward options that include more aggressive, often customized therapeutic strategies," Glinsky said. "Many of those patients can consider clinical trial options that they may otherwise have overlooked or not feel justified. "If you identify the ones ...Researchers make gains in understanding antibiotic resistance
... analytical technique, intense beams of x-rays are directed through crystals of proteins. The underlying atomic structure of the proteins is deduced by analyzing the pattern of diffraction of the x-rays. Steitz's group used ribosomal subunits from the primitive archaebacterium Haloarcula marismortui (Hma), ......xample of a "targeted" therapy -- an agent that is directed against a specific change in the cancer cell. Trastuzumab was approved for the treatment of advanced breast cancer in 1998. An estimated 211,240 women will be diagnosed with breast cancer in the United States in 2005. Of these, about 30 percent have...