Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
...d rivers with record production. "Our research is directed toward understanding why these runs see such different trends, by looking broadly at different systems subject to the same climate factors and constructing ecosystem conditions going back hundreds of years," Hilborn says. Hilborn is co-leader of the ......he modifications are made by a complex of proteins directed to target sites by integral non-coding guide RNAs. Drs. Michael and Rebecca Terns and colleagues have effectively reconstituted the archaeal modification guide ribonucleoprotein complex that guides pseudouridylation in vitro in a site-specific manne...Unexpected lock and key mechanism found for the assembly of tumor blood vessels
...g cancer clinical trials with an FDA approved drug directed against the integrin. Angiogenesis has been an intensely studied field of cancer research for the past 10 years. Since cancer cells literally hijack the body's normal angiogenesis process to initiate blood vessel growth to fuel the growth of tumors,...3-D study of immune cell interactions reveals details of an effective antibody response
...ntil recently there has been no way to observe the directed migration processes that guide the lymphocytes to ...s discovered, involves a combination of random and directed behaviors: B cells that have encountered antigen first move randomly along the follicle outskirts. T...Researchers develop new method for facile identification of proteins in bacterial cells
... this patent-pending methodology. Inquiries may be directed to Deborah Alper at the Johns Hopkins Bloomberg School of Public Health at dalper@jhsph.edu or 443-287-0402. "Identification and Phenotypic Characterization of Sphingomonas wittichii Strain RW1 by Peptide Mass Fingerprinting Using Matrix-Assisted L...Scientists reveal how disease bacterium survives inside immune system cell
...ases (NIAID) of the National Institutes of Health, directed the work at RML, in Hamilton, MT, in collaboration with lead author Dori L. Borjesson, D.V.M., Ph.D., of the University of Minnesota in St. Paul. Scientists analyzed how neutrophils from healthy blood donors respond to Anaplasma phagocytophilum, a ti...Mount Sinai School of Medicine establishes Stem Cell Institute
... Stem Cell Institute. The Institute, which will be directed by Gordon Keller, PhD, Professor of Gene and Cell Medicine, will integrate research in embryonic stem cells, developmental biology, and adult stem cell biology. "Stem cell research is an emerging and critically important science that has enormous p...By creating molecular 'bridge,' scientists change function of a protein
...ein folding, structure, function and dynamics; and directed evolution that mimics natural evolution in a test ...g some intermediate functions followed by stepwise directed evolution of these intermediate functions. If done, it gives you the ability to create protein funct...Killer dinosaurs turned vegetarian
... study were fossil preparator Donald DeBlieux, who directed excavation for the Utah Geological Survey, and George Washington University therizinosaur expert James M. Clark. The study was funded by a $100,000 grant from the Discovery Channel to the Utah Geological Survey, which provided a matching $100,000. A...... to forget. The authors trained five pigeons on a directed forgetting test, a variation on the classic match-to-sample test. After viewing sample stimuli consisting of one of two shapes (a circle or dot) or colors (red or white), the birds were cued to remember or forget the sample (signaled by either a hig...Chromosome deletion predicts aggressive neuroblastoma
...oblastoma research program at Children's Hospital, directed by John M. Maris, M.D., the senior author of the abstract. Co-authors of the study, in addition to Drs. Attiyeh and Maris, included Katherine K. Matthay, M.D., of the University of California, San Francisco; and Yael P. Mosse, M.D., of The Children's...Protein targets tumor vasculature, delays tumor growth in animal study
...ctor (sTF) genetically fused to antibody fragments directed against mouse or human vascular cell adhesion molecule 1 (VCAM-1), an antigen found on the inner surface of tumor blood vessels, which is the first site within the body that is exposed to intravenous drugs. They examined the activity of the proteins ...Data confirm panitumumab single-agent antitumor activity in patients with mCRC
... of panitumumab, a fully human monoclonal antibody directed against the epidermal growth factor receptor (EGFr...-EGF) is the first fully human monoclonal antibody directed against EGFr and is being evaluated as both a monotherapy and in combination with other agents for t...DuPont announces additional $25 million funding for DuPont MIT alliance
...al sciences to develop new materials and processes directed at bioelectronics, biosensors, biomimetic materials, alternative energy sources and new high-value materials. DMA also has provided an opportunity for DuPont to collaborate with MIT's Sloan School of Management to define new business models for these...Polymer expert writes text about better, inexpensive ways to create plastic
...ts to supply the rest of the information. Xanthos directed the Polymer Engineering Center at NJIT until 2003. Xanthos studied chemical engineering at the University of Toronto, where he received his doctorate in 1974. He has been Manager of Research and Development and Technical services at Marietta Resource...Researchers discover underwater volcano
...n that this volcano existed. When sound beams were directed into the crater this time, they measured an unusually shallow depth. These interesting results prompted further investigation of the area using the manned submersible Pisces V-a seven-foot sphere that has the capability to dive to depths of more than...Mount Sinai Hospital researcher develops Canada's first embryonic stem cell lines
...I). The use of the two new lines in Canada will be directed by the Stem Cell Network. The McLaughlin Centre for Molecular Medicine at the University of Toronto contributes to the support of a human embryonic stem cell core facility. The stem cell lines will be freely available to the Canadian scientific commu...NIH awards $11.9 M to The Burnham Institute to establish the San Diego Chemical Screening Center
... the Human Biomolecular Research Institute (HBRI), directed by John Cashman, Ph.D., President & CEO. "This is a merger of immense synergistic talents," said Dr. Houghten, "that will allow us to advance the discovery of new medicines at a pace heretofore unimaginable. We at TPIMS are very excited to be a pa...ASU's Curtiss awarded $14.8M from Gates Foundation to develop new pneumonia vaccine for newborns
...g countries. "It's shocking how little research is directed toward the diseases of the world's poorest countries," said Bill Gates, co-founder of the Bill & Melinda Gates Foundation. "By harnessing the world's capacity for scientific innovation, I believe we can transform health in the developing world and s......c Detector, which is being assembled by scientists directed by Frank Grunthaner at the Jet Propulsion Laboratory (JPL) in Pasadena together with Jeff Bada's group at UC San Diego's Scripps Institution of Oceanography. Skelley, a graduate student who has been working on amino acid detection with Mathies for fi...