Exercise doesn't work for us all
...ffect on their fitness or their risk of developing diseases like diabetes. "There is astounding variation in the response to exercise. The vast majority will benefit in some way, but there will be a minority who will not benefit at all," says Claude Bouchard of Louisiana State University in Baton Rouge. At ...Carnegie Mellon scientist develops way to deliver promising genetic tool into living cells
..., which could prove especially helpful in modeling diseases that involve multiple genetic mistakes occurring o...part the sequence of molecular events that lead to diseases such as cancer or diabetes in animal models. Ly is currently extending his research to show that GP...Zebrafish study yields observation of muscle formation
...s form is crucial to developing new treatments for diseases such as muscular dystrophy and to treating muscle injuries. However, while scientists have focused on muscle cells in culture, they know little about how muscle cells form in a developing embryo. In this month's issue of the journal Developmental ...Academy meeting highlights advances in detecting Amish, Jewish, and Icelandic genetic diseases
...on's medical future than ever before. For genetic diseases that are endemic among certain peoples, such as th...entify disease-related genes may prevent and treat diseases such as sickle-cell anemia, Tay Sach's disease, hemophilia, cystic fibrosis and others. What are som...Study reveals developing countries with recipe for thriving health biotech industries
...1975 and 1999, only 16 were for tropical and other diseases predominantly affecting developing countries -- an...ch more cost-effective way to deal with infectious diseases than drugs. India, for example, is developing vaccines for hepatitis B and C as well as South Africa...Less fat makes better process for designing new drugs
...ay use the method as a step in designing drugs for diseases such as cystic fibrosis, Alzheimer's, and tuberculosis. Proteins are part of the cell membranes of living organisms, and they are the gatekeepers that regulate what enters and leaves a cell, explained Martin Caffrey, professor of chemistry at Ohio...First analysis of chicken genome offers many new insights
...y of developmental disorders like cleft palate and diseases like muscular dystrophy. Researchers completed and made available the genetic sequence of the red jungle fowl -- a wild ancestor of the domestic chicken whose scientific name is Gallus gallus -- in March 2004. The genome provides several firsts: it ...UCSD researchers derive lessons about human evolution from chicken genome
...y of developmental disorders like cleft palate and diseases like muscular dystrophy. The draft of the chicken genome published in Nature is far from complete, but the focus now shifts to other efforts to sequence and analyze genomes and compare them to the human genome. The sequencing of dog and chimpanzee ...Researchers show how botulism toxin ensnares its target
...ntibiotics and vaccines already exist to treat the diseases in most cases, if they are caught early. In further studies, the researchers will extend their analysis to tetanus toxins, and to the other types of botulinum toxins. Such studies, he said, could reveal differences in how the toxins recognize their t...Hudson's Bay Company fur trapping policies set stage for modern environmental struggles
...cline in the Indian population by introducing such diseases as smallpox and measles. Schefke notes that in the first century of European contact, native populations declined by as much as 80 percent in parts of the Pacific Northwest and British Columbia. And along the lower Columbia River, the Indian populat...Discovery about Vitamin C explains its metabolic value
...le it may play in cancer but also in other chronic diseases such as heart disease, Alzheimer's disease, and autoimmune disorders. The toxic products produced by fat oxidation may not only be relevant to genetic damage and cancer, researchers believe, but are also very reactive compounds that damage proteins. ...Global bird populations face dramatic decline in coming decades, study predicts
...vengers to dead animals and limiting the spread of diseases to human communities as a result of slowly decomposing carcasses," the authors wrote. As an example, the researchers pointed to India, where the collapse of the vulture population in the 1990s was followed by an explosion of rabid feral dogs and rats...$43 million from Gates Foundation to produce inexpensive antimalarial drug for Third World
...a Rabinovich, M.D., M.P.H., director of infectious diseases at the Bill & Melinda Gates Foundation. "I hope th...rtnership could be a model for attacking neglected diseases in the developing world, said Jay Keasling, Ph.D., professor of chemical engineering at UC Berkeley,...Vaccinating wildlife can reduce human risk for Lyme disease
...be developed for Lyme and other vector-borne human diseases that are maintained by wildlife, including West Nile encephalitis. ...In wake of Lyme disease vaccine for people, mice may be next in line for shots
... "It shows us that with many emerging infectious diseases originating from animals, no one approach is likely to be a cure-all," Tsao said. "Diseases like this demand you think at the wildlife-community level, not just at the patient level." Lyme disease is caused by bacteria that multiples and incubate...New pathway identified in angiogenesis
...nicians a new way to intervene in a broad range of diseases and disorders, including cancer, heart and lung disease, wound healing and transplantation. Angiogenesis is a normal function in the body, but it's not always helpful. For example, while it is critical to normal embryonic development and beneficial i...New model of rare childhood blindness holds promise for testing preventive therapies
...de of finding cures for rare devastating childhood diseases beyond cancer," Dyer said. The LCA mice lack both copies of a gene called AIPL1, which is essential for the final development of light-sensitive cells in the retina called rods and cones. Rods are responsible for vision in lo...UT Southwestern researchers locate gene family involved in determining potential for acquiring lupus
...der this therapy are at risk to develop infectious diseases because their immune system is completely impaired. If we can understand what the suppressor gene is doing to block SLAM/CD2, we may be able to tweak the immune system back into normal balance." Other Center for Immunology contributors to th...Three Yale scientists receive Ellison Medical Foundation awards
...e most effective means of controlling insect-borne diseases has been to control the insects that carry them. C...vities through programs on aging and on infectious diseases of global health importance. The Foundation particularly wishes to stimulate new, creative research...New route to Parkinson's found in cells' 'garbage disposal' system
... a useful therapeutic target for neurodegenerative diseases such as PD."...