JCI table of contents, December 15 2004
... Staphylococcus aureus causes a wide variety of diseases including boils and furuncles and more serious diseases such as septicemia and pneumonia, and a debate has long raged about the existence of S. aureus "su......on for new methods of treatment for cardiovascular diseases through improved understanding of the biological and pathological processes in the vessel wall. The main topic of her research is programmed cell death (apoptosis) in the blood vessel wall, called the endothelium. Every cell carries in its DNA a kind...Return of the Staphylococcus aureus 'superbug'
Staphylococcus aureus causes a wide variety of diseases including boils and furuncles and more serious diseases such as septicemia and pneumonia, and a debate has long raged about the existence of S. aureus "su...Experimental Biology/Congress of the IUPS meets March 31 - April 6 in San Diego
...anding of healthy states as well as of why and how diseases develop and how they can be better diagnosed, treated, and prevented. When: Experimental Biology 2005 meets April 2 - 6. The IUPS Congress meets March 31 - April 5. In addition, a number of IUPS satellite symposia will be held within a 150-mile ...Science's Breakthrough of the Year: Salty, acidic soup could have supported life on Mars
...nes that could help researchers understand complex diseases or eventually produce genetically matched replacement cells for patients. Banner Year for Condensates: With an understanding of how to chill the two basic types of atoms into a single quantum state or "condensate" under their belts, researchers got...UCSD bioinformatics researcher studies tumor genome architectures with career award
... adds Raphael. "There are whole classes of genetic diseases that are inherited and passed down from a parent. Mutations in our DNA can be single-letter changes like those that occur in cystic fibrosis, or they can involve multiple chromosomal rearrangements such as those associated with solid tumors." Raphae...UGA's Center for Tropical and Emerging Global Diseases receives grant to train Brazilian scientists
...nformatics in the countries most affected by these diseases will help provide the needed researchers to do future cutting-edge science on these major public health problems." The first trainee, computer scientist Adriana de Andrade Oliveira, is slated to arrive at UGA by January. "We envision train...USF spin-out company Saneron CCEL wins federal award for cell therapy
...he new frontier of medicine for many patients with diseases that are untreatable today," said Stephen Klasko, MD, MBA, Vice President for Health Sciences and Dean of the College of Medicine at USF. "Saneron represents an entrepreneurial approach in an academic setting that will help patients and grow economic...Combined stem cell-gene therapy approach seen as potential treatment for cystic fibrosis
...development of adult stem cell-based therapies for diseases affecting the lung, heart and blood vessels. In addition to Drs. Kolls, Wang and Bunnell, other authors of the PNAS study include Richard G. Painter, Ph.D., Nicholas A. Lanson, Jr., Ph.D., and Donna Bertucci, from LSU; Blesilda C. Quiniones, M.D., Su...Potent anticancer drug increases function of axons in mouse model of neurodegeneration
...ebilitating diseases. Since many neurodegenerative diseases share or contribute to this pathology, the focus of therapy has been on drugs that break up these aggregates. Virginia M.-Y. Lee, PhD, Director of the Center for Neurodegenerative Disease Research, and Trojanowski introduced the concept of using micr...Tips from the Journals of the American Society for Microbiology
.... E. coli, one of the leading causes of food-borne diseases throughout the world, is responsible for more than 73,000 cases annually in the United States alone. E. coli O157:H7 can be life-threatening to children, the elderly and immuno-compromised patients. The intestinal tracts of cattle serve as the main ...Inexpensive, mass-produced genes at core of synthetic biology advances at UH
...nt of genetic disorders, debilitating neurological diseases such as Parkinson's and endocrine disorders such as diabetes. This technology may therefore yield profound benefits for human health and quality of life. "The technology developed by Dr. Gao and her collaborators has the potential to make research...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
...celerate research on brain tumors and neurological diseases that result from mutations in these switch genes called "transcription factors." When these genes are altered, the genes they control can go awry, causing abnormalities in the development or function of nerves and related structures. Although the g...University of Chicago researchers discovered that humans are a 'privileged' evolutionary lineage
...ion of the human brain more likely to be linked to diseases of the human brain? What happens when something goes wrong in these genes? Does it create neurological and psychiatric problems such as mental retardation or addiction? Could these genes contribute to IQ differences in humans? Do people with a partic...Growth of common skin cancer blocked in gene-switch mice
...has been implicated in a number of different human diseases and neoplasms, including BCCs in skin and cancers arising in brain, lung, prostate, pancreas and other gastrointestinal organs. Dr. Dlugosz and colleagues focused on the function of uncontrolled Hh pathway signaling in the growth of BCC. The investi...Fox Chase Cancer Center scientists discover key proteins linked to aging and cancer
...rlie the human aging process and have an impact on diseases of aging, such as adult cancers. "Most importantly, the failure of cells to stop growing through differentiation or senescence can lead to the uncontrolled growth of cancer," Adams emphasized. Both senescence and differentiation involve reorganizati...Suspect protein found to play protective role in chronic lung disease
... mitigating the damage caused by chronic pulmonary diseases such as asthma, University of Texas Medical School... the lung that resembles that seen in chronic lung diseases such as asthma, chronic obstructive pulmonary disease (emphysema, for example) and pulmonary fibrosi...A key signaling molecule in osteoarthritis is identified
...ch is actually a group of overlapping but distinct diseases with similar clinical outcomes, is most common form of arthritis. It is characterized by the breakdown of cartilage, which cushions the ends of bones, in the joints of the knees, hips, feet and back. This cartilage breakdown causes the bones to rub a......rculating in women with lupus and other autoimmune diseases can also cross the placenta and cause congenital heart block in the fetus. Scientists in Sweden now show how these antibodies cause heart cells to become paralyzed and eventually die, according to a study in the January 3rd issue of The Journal of E...NSBRI news: Bone-quality assessment tool for space and Earth
...openia and osteoporosis," Qin said. "Because such diseases are essentially painless at the initial stages, they are difficult to pinpoint and often diagnosed late." The SCAD project is complemented by NSBRI teams looking at other space health concerns including adequate sleep, psychosocial factors, cardiova...