Protein transformation gives new twist to medical research
...o treatment for some of the most difficult to cure diseases such as cancer and HIV. Lyz is a lysozyme, a protein that degrades the tough cell wall that covers bacterial cells. The name lysozyme means break-out enzyme as coined by Alexander Fleming, who was also the inventor of penicillin. Lysozymes are ...Backcountry water quality tests are good news for campers
...esentations to wilderness rangers about infectious diseases and backcountry medicine."We've also analyzed water at many more Sierra Nevada lakes and streams this past summer with consistent results. It's not surprising that waterways below roads, popular trails and well-used cattle grazing areas often show th...Put science at center of decision-making on third world development, experts tell UN
...medical tools that quickly and accurately diagnose diseases like AIDS and malaria. "The report does not tell countries how to implement these measures but instead offers a wide variety of 'lessons learned' to illustrate how developing and developed countries have used science, technology, and innovation to ac...Mutations in transporter protein shed light on neurodegenerative disorders
...lar Biology journal. The free sialic acid storage diseases are a range of rare, autosomal recessive, neurodeg...c acid storage disease (ISSD). "Clinically, these diseases consist of a spectrum," notes Dr. Richard J. Reimer of Stanford University. "In the severe phenotype...Stowers researcher answers fundamental question of cell death
...y help maintain cell survival in neurodegenerative diseases such as Alzheimer's disease." "Dr. Du's findings answer a fundamental question of apoptosis and have implications for a wide variety diseases," says Robb Krumlauf, Ph.D., Scientific Director of the Stowers Institute. "These findings are an exam...Searle grant funds proteomics initiative
...s of normal cells with those of cells afflicted by diseases and disorders. Breakthroughs in understanding prot... treatment of cardiovascular and neurodegenerative diseases and cancer. For example, proteins that go awry and interfere with the normal functioning of neurons ...New comparative toxicogenomics database
...t is becoming increasingly well accepted that many diseases involve interactions between environmental factors and genes. We integrate key data from diverse species, such as gene sequences, chemicals, and references, to provide a comparative perspective on gene-chemical interactions. This perspective is crit...The Louis-Jeantet-Prize for Medicine 2005
...so contribute to our understanding of the basis of diseases that affect traits specific to humans, for example speech or cognitive abilities. With the Louis-Jeantet Prize for medicine, Svante Pääbo wants to study the function of genes which were positively selected in human evolution that show diffe...Erkki Ruoslahti of The Burnham Institute named recipient of 2005 Japan Prize
...ng the etiology and developing therapy for serious diseases such as malignant tumors". Dr. Ruoslahti is being recognized for his seminal contributions to the cell adhesion field, which includes the discovery and molecular definition of the site at which cells attach to one another, the peptide RGD. Dr. Ruos...EB and IUPS - Where cures of tomorrow can be seen in the science of today
...ding of healthy states as well as why and how many diseases develop and how they can be better diagnosed, trea... development, prevention, or treatment of specific diseases and disorders such as parasitic and fungal infections, asthma and allergic reactions, cancer, and tr...UCLA/VA researchers discover fat gene
...it may present a target for the treatment of human diseases related to both excess and insufficient fat." In an unexpected finding, the study also discovered that lipin levels helped the fat cells metabolize glucose more efficiently, leading to lower blood-sugar levels. The obese mice with excess lipin in th...First birth using PGD to save baby from rhesus blood disease
...nce its introduction in 1990 to detect single gene diseases such as cystic fibrosis, or to screen for chromosomal disorders. But, in this case the research team used the technique to select an RhD- embryo from among a number of embryos produced after the mother underwent IVF treatment. The technique involves ...Novel asthma study shows multiple genetic input required; single-gene solution shot down
...nt implications for the genetic analysis of common diseases in a human population." The retained regions on chromosomes 2 and 6 "have conserved synteny distributed among 7 human chromosomes. A comprehensive analysis of these regions using association analysis may prove fruitful for uncovering additional loc...Intelligence in men and women is a gray and white matter
...esearch on dementia and other cognitive-impairment diseases in the brain." Study results appear on the online version of "NeuroImage." In general, men have approximately 6.5 times the amount of gray matter related to general intelligence than women, and women have nearly 10 times the amount of white matter r...Born to run? Capacity for aerobic exercise linked to risk of heart disease
...ts to identify people most likely to develop these diseases as they get older. The rats are available for stud...uction that may underlie the development of common diseases in humans," Britton adds. "And, while our results are intriguing, future research will be needed to ...Priming embryonic stem cells to fulfill their promise
... sought as possible treatments for dozens of human diseases and health conditions. Sangeeta Bhatia and Shu Chien, UCSD bioengineering professors, and Christopher J. Flaim, a bioengineering graduate student, described the cell-culture technique in a paper published in the February issue of Nature Methods, whic...Plant protein mimics hormone that mitigates diabetes and obesity
...ant protein could play a role in the prevention of diseases like diabetes as well, because it has the same target as adiponectin in mammal cells - the adiponectin receptor." The binding of hormones and other proteins to receptors activates specific responses. For example, when the hormone oxytocin binds to ce...UCI researchers create new technique for speeding development of vaccines
...ate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis. Because the new technique can synthesize a large number of proteins very quickly, it has potential to accelerate vaccine development, particularly crucial in the fight against bioterrorism. The technique is...How do cells travel through our bodies?
...turbance can lead to the spread of cancer cells or diseases like Spina bifida and Lissencephaly, in which cell...cess, we're one step closer to understanding human diseases that result from uncontrolled cell migration. N-cofilin is not only essential for cells to move, but....... Such mathematical models could help characterize diseases in which a system is unable to return to its normal state, is set to a wrong state (e.g., glucose fluctuations in diabetes) or a control is missing, such as the proliferation of cells in cancer, or the absence of an enzyme that results in an inherite...