Hopkins scientists uncover 'tags' that force proteins to cell surface
...ical step in drug development is to get cells in a dish to express the protein you want to target with drugs, and then to test thousands of molecules to see which ones interact with the protein and have the effect you want," says the study's senior author, Min Li, Ph.D., a professor of neuroscience at the...Phytochemicals may protect cartilage, prevent pain in joints
... 2 enzymes. They added these phase 2 inducers to a dish containing the chondrocyte cells that are crucial to maintaining healthy joints. After 24 hours, the cells were subjected to a stress test designed to mimic aspects of strenuous exercise on a joint as well as the hydrodynamic environment in a bioreac...New class of antibiotics effective against drug-resistant bacteria discovered in fungi
...Penicillium, which had landed by chance in a Petri dish produced a substance that eliminated colonies of staphylococcal bacteria. "Most antibiotics used by humans are produced by fungi and certain soil bacteria," he said. "Using our existing tools of discovery, we have failed to uncover any new classes o...Center releases new public survey on stem cells
...ber of Americans believe that an embryo in a Petri dish has no or low moral status (30 percent) or maximum... A third of those who believe an embryo in a Petri dish has maximum moral status nonetheless approve of ESC research. Similarly, a third support ESC resear...Researchers use 'trickery' to create immune response against melanoma
... mice were removed, combined together in a culture dish and exposed to pieces of viruses and bacteria. The researchers used the most aggressive mouse melanoma tumor, B16, which has multiple mechanisms to escape the immune system that are similar to those used by human cancers. They found that the dendriti...Study identifies several new bacterial species associated with common infection in women
...rchers said. Rather than grow bacteria in a Petri dish the standard identification method Fredericks harvested DNA from bacteria, cloned segments of the DNA and used polymerase chain reaction (PCR) assays to analyze and sequence the segments. PCR analysis has a high degree of sensitivity and specificity....Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
...lls to become dopamine-producing in the laboratory dish in only three weeks, compared to the five-to-eight... we could generate a process in the tissue culture dish that is simple, rapid, and uses defined reagents, most of which are human products. We can make them...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...ey first tested the two versions in the laboratory dish in two different breast cancer cell lines and in a mouse cell control. In a proof of concept study, they found evidence that the alternating LHRH and lytic peptide on the ironoxide particle was effective at killing cancer cells, suggesting that the c...War on terror meets war on cancer
... of a tumor, the cancer cells can be cultured in a dish to determine how rapidly they grow. "But if you can't biopsy it because it's in your brain or another hard-to-reach location, then you need some other way to figure out how fast it's growing," Hegg says. Such a test would involve taking a blood sam...Student scientists create living bacterial photographs
...visers, Dr. Andy "Escherichia" Ellington--onto the dish of bacteria growing at body temperature in an incu...aph. Bacteria in the lighted regions of the Petri dish don't produce the pigment and appear light. Those in the dark regions produce pigment and appear dar...Study hints at role of stem cell genes in testicular, breast cancers
...sample of breast cancer cells grown in the culture dish and tissue from a Stage 3 breast tumor. Previously, the team had discovered that expression of the genes was elevated in two samples of seminomas (Stem Cells, March 2004). In the current study, they expanded their investigation, determining that the ...New nanosensor uses quantum dots to detect DNA
...d the two DNA probes, plus a quantum dot, in a lab dish containing the DNA they were trying to detect. Then nature took its course. First, the two DNA probes linked up to the target DNA strand, holding it in a sandwich-like embrace. Then the biotin on one of the probes caused the DNA "sandwich" to stick t...OHSU discovery sheds light into how stem cells become brain cells
...f brg-1 in neuronal stem cells either in a culture dish or in the brain to replace the lost dopamine-producing cells. Another possibility would be the replacement of lost or damaged motor neurons in patients who have suffered brain or spinal cord damage. This research was funded in part by the Medical Re...Wisconsin scientists grow two new stem cell lines in animal cell-free culture
...dy generally requires providing the cells in a lab dish with the right mix of nutrients, hormones, growth factors and blood serum. But those methods have often depended on animal cells - such as those obtained from mouse embryos in the case of embryonic stem cells - and other animal products to keep the ...Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
...pson and Ehtesham looked at CXCR4 more closely, in dish studies. They wanted to determine whether cells that have CXCR4 invade more than cells without the molecule. They induced glioblastoma and forced the cells to migrate, comparing migrating brain tumor cells with the cells at the origin of the cancer. ...Powerful technique for multiplying adult stem cells may aid therapies
...d the stem cells in the lab and cultured them in a dish by themselves, they died. When he mixed them with these newly discovered cells, they thrived. But how did these new cells manage to sustain the stem cells so dramatically? Zhang used a microarray platform to search for genes that were active in these...Breakthrough for stem cell research
... animal tissue to keep the hESC alive in the petri dish or as a culture to grow it on," said Dr Sidhu. "Those animal products have the potential to transmit retroviruses in humans, which could have disastrous consequences." Human embryonic stem cell lines are derived from specialized cells from embryos d...Science class experiment reveals vitamin B12 secret
...ed with bacteria. In contrast, seedlings sharing a dish with the most obviously defective bacteria were st...subsided to a more uniform fluorescence on the lab dish with the laundry whitener. And in the lab dish with the seedlings, the restored bacteria produced a ...Hunting down the causes of Huntington disease
...rexpressing HSJ1b in neurons grown in a laboratory dish protects them from polyQ-huntingtininduced death. Next the researchers created worms that had neuron dysfunction due to the presence of polyQ-huntingtin, and found that the dysfunction could be reduced by HSJ1b. To identify the mechanism by which ...Eavesdropping fringe-lipped bats spread culture through sound
...he "oohs" and "aahs" of a customer eating the same dish the next table over, frog-eating bats learn to eat new prey by eavesdropping on their neighbors as they eat, report biologists from The University of Texas at Austin. Rachel Page and Mike Ryan, studying fringe-lipped bats at the Smithsonian Tropical ...