Subtle signs can help predict Huntington's disease early
...my of Neurology. Huntington's disease is a genetic disorder that affects movement, thinking, and some aspects of personality. There is no treatment or cure for the disease. "These results will help us understand how and who will develop Huntington's, which is important information as potential treatments ar...UCLA researchers discover link between Parkinson's and narcolepsy
...n's shares other symptoms with narcolepsy, a sleep disorder characterized by sudden and uncontrollable episodes of deep sleep, severe fatigue and general sleep disorder. Now a team of UCLA and Veterans Affairs researchers think they know why the two disorders share something in common: Parkinson's disease...Protein interactions targets for Huntington disease therapy
...gtons disease is a devastating, fatal neurological disorder that affects an estimated 30,000 Americans. It is dominantly inherited, which means that if a person inherits a single copy of the gene from a parent, that person will develop the disease usually in middle age. Children born to parents who go on to ...Study finds regions of DNA that appear linked to autistic spectrum disorders
...tionally in searches for autism genes. Autism a disorder that involves social deficits, language problems and repetitive, stereotyped behaviors affects around one in 1,000 children. And the combined incidence of autism spectrum disorders, which include Asperger syndrome and pervasive developmental disorde...NIH awards VBI, Mayo Clinic $2.4M to study chronic rhinosinusitis
...ther proteins contributing to the pathology of the disorder has proved elusive." The new project will involve a transdisciplinary team of immunologists, allergy physicians, otorhinolaryngology surgeons, and genomic scientists. Principal Investigator Hirohito Kita, professor of medicine at the Mayo Medical ...Genetic roots of bipolar disorder revealed by first genome-wide study of illness
The likelihood of developing bipolar disorder depends in part on the combined, small effects of...s found in the scans of 413 adults who had bipolar disorder with variations found in the scans of 563 healthy adults. By pooling the genetic material of the ...Story ideas from the Journal of Lipid Research
...Syndrome. People with Down Syndrome a genetic disorder due to the presence of an extra chromosome 21 develop Alzheimer's disease (AD) earlier (mid- to late 30s) than the general population (mid- to late 70s). To understand why, scientists have studied genes from chromosome 21 that are also involved in A...UCSF-led team receives $15 million to study genetics of epilepsy
...lthough it has been known since antiquity that the disorder is influenced by inherited genes, progress to date...,750 patients and 3,000 people who do not have the disorder so-called "controls" used for comparison -- over the course of the study. Details about each p...Study of damaged gene gives insight into causes of mental illness
...ile the causes of schizophrenia, bipolar affective disorder and major depression are unknown, all the evidence points to subtle differences in the way the brain develops and to chemical changes in the brain. Our previous work identified the DISC1 gene as an important risk factor in these types of mental illn...Gene malfunctions cause schizophrenia, depression symptoms in mice
...growing recognition that schizophrenia and bipolar disorder share, at least in part, common genetic etiologies and thus underlying molecular mechanisms." ...Delayed treatment of childhood-onset bipolar disorder results in negative outcome in adults
...mally high energy and extreme depression. Bipolar disorder is estimated to affect approximately 1-3% of adult... affect children and adolescents. Untreated, this disorder is associated with greater risk of drug and alcohol addiction, of interpersonal relationship difficu...New treatments have major impact on heart failure rates
...ablished a decline in heart failure a progressive disorder when damage to the heart weakens the cardiovascular system and poor heart muscle function causes fluid in the lungs. This is the first time such findings relating to heart failure, a chronic condition often requiring specialised nursing care in the...Salk scientist Ursula Bellugi elected to National Academy of Sciences
... basis of behavior.This puzzling genetically based disorder leaves language, facial recognition and social ski...vere inadequacy in other cognitive aptitudes. This disorder arises from a faulty recombination event during the development of sperm or egg cells. As a result, ...Army research mission focused on autism
...nosed with autism. Autism is a developmental brain disorder that affects as many as 1 in 150 children as repor...that advances the understanding of autism spectrum disorder and leads to improved treatment outcomes." "We need to move to a place in research where we are mak...Young children with epilepsy seizures could benefit from animal model of disease
...y seizure seen in infancy and early childhood. The disorder involves a sudden bending forward and stiffening o...n Academy of Neurology. Since children with this disorder often develop it without any apparent cause, such a mouse model will also improve the likelihood of ...Deactivating protein may protect nerve fibers in MS
...have increasingly viewed MS as a neurodegenerative disorder rather than simply an inflammatory one. Loss of nerve cells, injury to nerve fibers and atrophy within the central nervous system occur progressively from the start of the disease, eventually leading to permanent disability, especially in patients wh...New genes identified in childhood fever-related seizures
...ted (febrile) seizures are the most common seizure disorder in children and affect two to five percent of chil...ped epilepsy later in life. The 13 affected by the disorder and 13 additional family members not affected by the disorder took part in the genetic study. The...Study links faulty DNA repair to Huntington's disease onset
...untingtons disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. But a new discovery about how cells repair their DNA points to a possible way to stop or slow the onset of the disease. The research was funded by the National Institutes of Health (NIH)....Susceptibility to Crohn's disease -- an important new clue
Crohns disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated ...ptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications. Researchers from the University of Lig......polar disorder, or attention deficit hyperactivity disorder (ADHD). "Our data reveal how the brains arousal sy...of DISC1 in patients with schizophrenia or bipolar disorder would increase vulnerability to cortical network disconnection and profound PFC deficits. This may b...