New therapy for specific form of leukemia
...ir functioning disturbs the normal functioning and division of cells. Thus, such disorders in the functioning of ABL1 are a major cause of certain forms of leukemia. Existing drug now used with T-ALL patientsResearch performed by Jan Cools and his colleagues, under the direction of Peter Marynen, shows for t...DNA sequence controls expression of gene involved in cancer
...f bcl-2 in damaged cells can lead to the continued division of the mutated cells and eventually cancer. The expression of the bcl-2 gene is regulated both transcriptionally and posttranscriptionally. One way bcl-2 levels are controlled is through an adenine and uracil-rich sequence of nucleotides in the 3' ...Marine Biological Laboratory summer investigator wins Nobel Prize in Chemistry
...re about the role that ubiquitin plays in the cell division cycle. "Many important regulators of the cell c...an cells in hopes of learning even more about cell division in general and cancer more specifically. "Changes in the mechanisms that control the activity ...Electronics recycling made easy
...nd at www.onyxpak.com . The Electronics Recycling division of Onyx Environmental Services specializes in the recycling of potentially hazardous and harmful substances contained within lighting and electronics products. Onyx is continually developing effective recycling programs designed to help clients manag...Research into the sense of touch in worms wins Eppendorf/Science Prize
...ect, completed in 2001, focused on asymmetric cell division and the generation of cell diversity in the embryonic murine cerebral cortex. She is now a postdoctoral fellow in Dr. Sally Temple's laboratory working on mechanisms regulating neural stem cell self-renewal and cell fate choices, including interactio...Northeastern University and Massachusetts Biotechnology Council to host drug discovery day
...ic Research Technologies at the Genetics Institute division of Wyeth Ayerst Research and prior to that was a Senior Scientist/Associate Director in the Medicinal and Analytical Chemistry department at Genentech, Inc. WHERE: Monday, October 18, 20041 pm to 7 pm Northeastern University, Curry Student...Genetic data crunching achieves milestone at Stanford
...in the database to illuminate everything from cell division in yeast to cancer-causing genes to what happens to bacteria when they're deprived of iron. Microarray data have also allowed scientists to understand how various drugs affect the malaria bug, to find out what the immune system attacks in patients wi...New DNA repair enzyme makes mistakes to save lives of cells
...i, Ph.D., research associate in the basic research division at UPCI and the paper's first author. Additional studies also will provide researchers with more insight into POL-Q's role in preserving the integrity of the genome. Research performed at the Jackson Laboratory and published in Molecular and Cellula...Molecule that helps DNA replicate may make good target for cancer therapy
...uld be effective in stopping the uncontrolled cell division seen in cancerous tumors. The work grew out of a d...attach." If the complex cannot attach to DNA, cell division is stopped cold. The proteins that bring about DNA replication have been highly conserved during e...Humans and dolphins: If brain size is a measure, we're not that different
... years," says Rich Lane, program director in NSF's division of earth sciences, which funded the research. "Brain size, it turns out, increased significantly in two critical phases in the evolution of these animals." The first brain size increase occurred with the origin of Odontocetes from the ancestr...Human embryonic stem cells promising for replacement of blood supply
...fman, M.D., assistant professor of medicine in the division of hematology, oncology and lead researcher. "We can envision blood therapies completely compatible with the patient, such as use of embryonic stem cells to make red blood cells for platelets used in blood transfusions, or a source of new blood suppl...Researchers discover transport molecule that allows boron into cells
...lly in a specific concentration of boron, but cell division was inhibited when boron was too high or low. Biochemical tests confirmed that well-known signaling molecules that affect growth and development were activated when boron entered cells, and that reducing the activity of NaBC1 was sufficient to bl...Stowers Institute scientist named American Cancer Society research professor
...s transmit genetic information during routine cell division (mitosis) and during the process of creating gamet...w chromosomes are properly transmitted during cell division has direct implications for understanding cancer. In addition to his work at the Stowers Insti...Insecticide resistance in mosquitoes being studied
...trol disease-bearing mosquitoes, said Ray Parsons, division director. "History has shown that overuse of pesticides will lead to resistance in insects," Olson said. "Resistance can be prevented or managed if we have the knowledge about when and/or where to use and not to use them. The key here is ma...Rethinking new therapies for Crohn's disease at U.Va.
...al of Medicine , Dr. Fabio Cominelli, chief of the division of gastroenterology and hepatology at the University of Virginia Health System reports that a dysregulated response by the innate immune system- the body's initial, non-specific response to infection- may have more to do with the development of Crohn...Duchenne Muscular Dystrophy research focuses on early mechanisms
...t Virginia Tech; David Thomas, professor and head, division of structural biology and biophysics, and Dawn Lowe, assistant professor of physical medicine and rehabilitation, both at the University of Minnesota; and Chris Ward, assistant professor of biomedical science at the University of Maryland at Baltimor...UCLA scientists uncork fountain of youth for HIV-fighting cells
...heir protective functions. This massive amount of division shortens these cells' telomeres prematurely," explained Dr. Rita Effros, Plott Chair in Gerontology and professor of pathology and laboratory medicine at the David Geffen School of Medicine at UCLA. "So the telomeres of a 40-year-old person infected...Heart responds to fasting by remodeling vital energy-producing components
...o quantify. "Through the efforts of people in our division like Xianlin Han, who has worked hard to perfect the technology, we have been able to open up fresh avenues of investigation using shotgun lipidomics," Gross says....Visualizing the end of the human genome
...omes, a function that is essential for normal cell division and survival. By visualizing the protein as it sur...that organism. POT1 is critical to normal cell division and survival; experiments in fission yeast have shown that without it, most cells die immediately. C......le to respond to changing conditions and alter its division of labor. When you think of that type of flexibility and adaptability, you immediately think, 'who's in charge'? People from many scientific and engineering endeavors are fascinated by localized decentralized decision making." Huang said the system m...