Normal chromosome ends elicit a limited DNA damage response
...whole chromosomes end-to-end. During the next cell division the sorting mechanism, which ensures that each daughter cell receives a full complement of chromosomes would inevitably rip the fused chromosomes apart. "Such fusion breakage cycles scramble the genome over time, and cause genome instability, which ...Regenerating worms help elucidate stem cell biology
...and the many environmental cues that influence the division and differentiation of their neoblasts, Snchez Alv...hat without piwi, the daughter cells from this division failed to differentiate into a specialized cell once they'd reached their destination. Based on thei...Silenced gene in worm shows role in regeneration
...issue structure begin to be defined at the time of division of its parent cell. "Once the smedwi-2 molecule i...ssue damage or homeostasis signals. The stem cell division progeny failed to migrate to the appropriate tissues. The daughter cells didn't know how to differe...UK is first to administer new anti-clotting technology
...cations." "The research capacity of the cardiology division at UK has skyrocketed in the last year. Millions o..., professor and vice chair of medicine, and chief, division of cardiovascular medicine, UK College of Medicine, and co-director of the UK Gill Heart Institute. ...Yale scientists decipher 'wiring pattern' of cell signaling networks
...o carry out complex processes such as growth, cell division and formation of complex cell types such as brain cells and intestinal cells." Over the past several years, a large volume of information on genes in organisms as diverse as man, mouse, baker's yeast and viruses has been generated. While genomic DNA...FDA approves AVELOX (moxifloxacin HCl) for treatment of complicated intra-abdominal infections
...artment of surgery and director of research of the division of trauma/critical care at the University of Cincinnati College of Medicine. With this FDA approval, AVELOX is indicated for the treatment of adults with cIAI, including polymicrobial infections such as abscesses caused by Escherichia coli, Bacteroi...UC Davis wins $8 million EPA grant to study health effects of air pollution
...health issues," said Deborah Jordan, the EPA's air division director for the Pacific Southwest Region. "With this grant UC Davis will further the EPA's understanding of particulate matter exposure and its health effects on adults and children." The campus's new San Joaquin Valley Aerosol Health Effects Center...Researchers say estrogen can kill breast cancer cells once fueled by the hormone
...nt and scientific director for the medical science division at Fox Chase. "However, cancer cells are smart and they figure out how to survive these treatments. We believe we've become savvy to their art. Our laboratory study demonstrates that these same breast cancer cells die when we re-introduce them to ...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...this new method, Bar-Joseph studied the human cell division cycle. Considered one of the most important biological systems, the cell cycle plays a major role in cancer. Using their new method, Bar-Joseph and his colleagues identified many new human genes that were not previously found to be participants in th...Biodesign Institute awarded $3.2 million to develop vaccine to thwart biothreat
...nal Institute of Allergy and Infectious Disease, a division of the National Institutes of Health. Other members of the consortium include the Cerus Corporation, Lovelace Respiratory Research Institute and the University of Texas, San Antonio. "The funds for this research will be important in developing str...'Computer-chemistry' yields new insight into a puzzle of cell division
...lead to anticancer drugs to block the runaway cell division behind some cancers, said the researchers. Signif...this brief docking accomplish its role in the cell division cycle, said Rudolph. That biochemical role is for the enzyme to remove the phosphates from two phosp...New study shows Emezine demonstrates more efficient absorption
...Marketing for Accentia's specialty pharmaceuticals division said, "Prochlorperazine is widely used for the relief of nausea and vomiting however physicians outside the hospital and clinic have been limited to prescribing a suppository or standard oral swallow tablet. In our market research, physicians respon...Learning about sex from an elegant worm
...cret of sex is meiosis, a specialized kind of cell division in which a cell replicates and then divides twice ...oducing organisms employ checkpoints at which cell division may be halted and defective cells made to self-destruct through programmed cell death (apoptosis). I...Columbia University Medical Center researchers discover potential mechanism for tumor growth
...ls are susceptible to a specific error during cell division that can result in severe chromosomal defects. Thi...g force of tumor progression. The process of cell division is closely monitored by the cell, because a mistake can result in a cancer-causing chromosome abnorm...JCI table of contents: December 15, 2005
...heckpoint in the cell cycle during replication and division allows incorrectly re-joined breaks in chromosomal DNA to go unrepaired, causing leukemia. Their results will be reported online on December 15 in advance of print publication in the January 2006 issue of the Journal of Clinical Investigation. After ...Cancer support cells may evolve, fuel tumor growth, study shows
...ted rate. First, they found that this accelerated division triggered a signal to fibroblasts, connective cells in the surrounding supporting tissue, to grow and proliferate. The signal then induced a tumor suppressor, p53, within the fibroblasts, which stopped this action. Thus, a change made only in epithel...Genetic testing still smart choice, despite uncertainties
... but to natural errors occurring during early cell division in the embryo." Extracting test cells before the embryo divides a third time could reduce the number of misdiagnoses because of mosaicism, the UF researchers suggest. Improving culture conditions could help too, Kovalinskaia said. But the small margi...Molecular imaging allows detection of plaques likely to rupture
...coronary plaques, said Petrov, a researcher in the division of cardiology at the University of California at I....D., Ph.D., professor of medicine and chief of the division of cardiology at the University of California, Irvine. Besides Petrov and Narula, authors of "Resolu...... the skull. A group led by Yang Chai, chair of the division of craniofacialsciences and therapeutics in the USC School of Dentistry, hasidentified the genetic factor leading to malformation of theforehead and frontal part of the skull. The discovery was publishedonline Dec. 20 by the journal Development. Chil...ASU researchers find link between social behavior, maternal traits in bees
... still influence foraging behavior, resulting in a division of labor between pollen-foraging and nectar-foraging worker bees. To test this hypothesis, Amdam set up a race of sorts to determine which strain of worker bees became reproductively active the fastest. She separated the high and low pollen-hoarding ...