Brown-Harvard team solves mobile DNA's surgical sleight-of-hand
...(λ-INT), the protein responsible for this DNA doctoring in the lambda virus, which infects and lives off Escherichia coli (E. coli) bacteria. The findings are important because lambda is a model virus used to understand mobile DNA, according to Arthur Landy, professor of medical science in the Department ...Brown scientists map structure of DNA-doctoring protein complex
...nes into the chromosomes of target cells. This DNA doctoring not only shapes species over time, it also spreads antibiotic resistance and is used by bacteria that spread Lyme disease and by viruses linked to certain forms of cancer. Last year in Nature, scientists working in the Brown University lab of Arthu...