HHMI researchers Richard Axel and Linda Buck win 2004 Nobel Prize
...ely clever twist." She made three assumptions that drastically narrowed the field, allowing her to zero in on a group of genes that appear to code for the odorant receptor proteins. Her first assumption--based on bits of evidence from various labs--was that the odorant receptors look a lot like rhodopsin, the re...New method identifies chromosome changes in malignant cells
...d. "If a cell really wants to change its behavior drastically -- if it is a cancer cell or something has changed in its environment -- the fastest way is just to amplify or delete a chunk of chromosome," said Troyanskaya. "We needed a way to identify these deletions and amplifications very accurately." The new...Anti-cholesterol drug treats Alzheimer's disease in mice
...drug that jams a key enzyme regulating cholesterol drastically reduces the levels of brain-clogging amyloid plaque in mice engineered to have a human form of the amyloid protein. According to Dora Kovacs and her colleagues, the findings suggest that such inhibiting drugs could be used to treat and prevent Alzhei...Cars, not crops, should be chief targets in reducing greenhouse gases
... alternative energy sources, will have to increase drastically for the country to meet the challenges of reducing its impact on global climate and achieving a more energy-efficient economy. ...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...eimer's disease protects brain cells in culture by drastically reducing the neurotoxic amyloid protein aggregates that are critical to the development of the disease. The treatment involves dispatching a small molecule into the cell to enlist the aid of a larger "chaperone" protein to block the accumulation of t...Prominent physicist Freeman Dyson to speak at NJIT: Promises and perils of genetic engineering
...hnology change the course of Darwinian evolution - drastically altering the nature of life on earth? Internationally-known physicist and futurist Freeman Dyson, of Princeton University's Institute of Advanced Studies, will explore this possibility during the Nov. 10 technology forum sponsored by the New Jersey ...Studies in Royal Society journals include stress in birds and depletion of medieval fish stocks
...rd predator-prey model these functions may lead to drastically different predictions of the population dynamics in this system. Predictive models should be analyzed and interpreted with great caution whenever the mathematical functions used in them are approximations of biological processes. Contact: Dr Gregor F...Loss of fruit fly retina protein delays blinding light damage
... researchers also found that rhodopsin levels were drastically lower after three days of exposure and virtually gone by day 13. In genetically engineered flies whose rhodopsin destruction was inhibited in various ways, the researchers found no or relatively minor loss of the light-induced signal until much later...Albatross study provides new information vital to their conservation
...tic birds. The right combination of measures will drastically reduce deaths."...Sexual cooperation: Mating increases longevity in ant queens
...ose lifespan and future reproductive output can be drastically reduced. New findings suggest that in some social insects--in which both sexes ultimately benefit from long, successful reproductive lives of females--sexual cooperation, rather than sexual conflict, may be favored. The findings, reported in the Feb...New findings lead researchers to question basic assumptions of fisheries management
...erkeley, however, elimination of older generations drastically reduces the ability of the population to replenish itself. Failure to account for the role of older fish in maintaining healthy populations may help explain the recent collapse of some major West Coast fisheries. The Pacific Fishery Management Counc...Essential mangrove forest threatened by cryptic ecological degradation
...grow crops inland, at the same time such practices drastically affect the coastal zone by introducing an excess of fresh water. The consequences range from adverse shifts in the composition of mangrove tree species to disrupted ethnobiological relationships, lagoon fisheries, and many additional functions provid...USGS workshop on the impact of carbon dioxide on marine life
...ons of CO2 will significantly impact our oceans by drastically altering their pH balance," explained Feely, co-author of a study on CO2 and the oceans published in a 2004 issue of the journal Science. The lower pH of ocean water means that organisms such as those that form coral reefs and many planktonic organi...Ume researchers have mapped the dams of the world
...at The Nature Conservancy in the U.S. Humans have drastically changed many rivers by impoundments and diversions to meet the needs of water, energy and transportation. Such exploitation belongs among the most dramatic, deliberate impacts that humans have had on the natural environment. Many of the ecological ef...Next-era targeted therapy overcoming Gleevec's shortcomings
...ents develop mutations in the Bcr-Abl protein that drastically reduce Gleevec's effectiveness. AMN107 Holds Promise for Treating Gleevec-Resistant Leukemia According to Oregon Scientists: Abstract 5282 To overcome resistance to Gleevec, scientists are designing new compounds that bind tighter to the intended ta...Researchers develop assay that could be applied to drug screening
...in latrunculin B, a toxin found in Red Sea sponge, drastically reduces the efficiency of membrane scission and affects many aspects of CCP dynamics."...Georgia Tech develops mass spectrometry device that analyzes proteins faster and at a lower cost
.... In addition, AMUSE is a nanoscale ion source and drastically lowers the required sample size by improving sample use. Also important, AMUSE is a "high-throughput" microarray device, meaning that it can analyze many more samples at a time than a conventional electrospray device. This innovation will be particu...First test of predictions of climate change impacts on biodiversity
... solution. "The accuracy of the predictions can be drastically increased if a set of alternative models are compared and used together to create a 'consensus' projection" Says Dr Arajo. Using the same data set for British birds, the consensus prediction was shown to be vastly superior to any single model and cou...Meaningless sex? Male mounting reduces sexual promiscuity of females
...ing alone (independently of insemination) not only drastically inhibits the propensity of a hen to mate with a new rooster but also reduces the number of sperm that she obtains from a new rooster in the 24 days following mounting. The researchers therefore showed that roosters can defend their paternity by reduc......roads, cemeteries, water tanks, and buildings have drastically fragmented Mont-Royal, home to four populations of red-backed salamanders (Plethodon cinereus). Stranded on this green oasis, these salamander populations have likely suffered from inbreeding and a dearth of gene diversity. Sarah Nol, Franois-Jose...