UCLA/Toronto researchers unlock key to memory storage in brain
...ies into healthy cells and away from sick cells in dying regions of the brain." Our memories define who we are, so learning how the brain stores memory is fundamental to understanding what it is to be human, Silva observed. "A memory is not a static snapshot," he said. "Memories serve a purpose. Th...JCI table of contents -- April 19, 2007
...e immune cells known as dendritic cells to take up dying pancreatic cells expressing ovalbumin and present the ovalbumin to CD8+ T cells (a process known as cross-presentation) in a form that they could "see". Cross-presentation required that the dendritic cells express activating IgG1 receptors. Because o...New treatments have major impact on heart failure rates
...ectively. Patients now have a much reduced risk of dying or having another stroke while being treated in hospital and are also less likely to suffer a stroke or further heart attack once they have been discharged. The study looked at patients between July 1999 and the end of 2006. Countries involved in t...Is climate change likely to increase disease in corals?
...nce of life. But in recent years, corals have been dying in droves. Scientists suspect a variety of factors, ranging from accidental damage from fishing activity to the effects of polluted runoff from land. One threat that appears to be growing dramatically in Australia's famed Great Barrier Reef is white ...HIV survival improves if patients stay in care
...ear after starting treatment had a greater risk of dying than those who saw the physicians at least once ea...visits in one quarter had nearly twice the risk of dying compared to patients with visits in all four quarters. "The next step is to figure out how to get ...Other highlights in the May 16 JNCI
...nown as FLIP may stop metastatic cancer cells from dying and could be a good target for drug development. ...vels of the FLIP protein prevent cancer cells from dying after they lose contact with their surroundings. The researchers also used chemical and genetic appr...K-State biologist hopes mosquito can break viral chain
...h of cells, or apoptosis. "Millions of cells are dying at any given moment in our body," Clem said. "And that's a good thing." Programmed cell death is tidier than necrosis, in which injury prompts inflammatory cells to rush in and clean up. In contrast, apoptosis relies on a cell's genes to trigger an...Jefferson scientists use gene therapy to reverse heart failure in animals
...in couldn't handle the stress of part of the heart dying and went on to develop heart failure. S100A1, part of a larger family of proteins called S100, is primarily found at high levels in muscle, particularly the heart. Falling levels of S100A1 are critical in the loss of heart-pumping strength after a ...Blood test may help signal tumor's remission, return in throat cancer patients
... a 3.8-fold, 3.0-fold, and 2.9-fold higher risk of dying of throat cancer, respectively. Patients with an i... in three or more factors were at highest risk for dying of throat cancermore than twice as likely as patients with an increase in two or fewer factors. Fina...Study warns climate change and deforestation will lead to declines in global bird diversity
...ies headed toward extinction are like thousands of dying canaries in coal mines," Dobson adds. "It's time we paid attention to them." "Billions of philanthropic and government dollars are spent annually on clearly crucial biomedical research to avert the future impacts of diseases," says Jetz of UCSD. "...Agonized death throes probable cause of open-mouthed, head-back pose of many dino fossils
...dy Museum. "Paleontologists aren't around sick and dying animals the way a veterinarian is, where you see this posture all the time in disease processes, in strychnine cases, in animals hit by a car or in some sort of extremis." Faux and Padian argue in Paleobiology that the dinosaurs died in this postur...JCI Table of Contents -- July 2, 2007
...he normal repair process cause the accumulation of dying cells in mechanically active tissues, resulting in muscular dystrophies and cardiomyopathy. The discovery of alternative, better-tolerated drugs that can drive the membrane repair process would represent a significant advance. TITLE: Dysferlin-medi...Cardiac patches stimulate regeneration, improve function after heart attack
...n more cardiomyocytes, far exceeding the number of dying cells. (For perspective, the average rat heart has about 20 million cardiomyocytes overall.) Kuhn, a pediatric cardiologist, envisions using a sustained-delivery periostin patch not only to treat adults with heart attack, but also to encourage car...Study points to new way to predict death risk from torn aorta
...he hospital, patients face a one-in-four chance of dying within a few years. And doctors dont have a reliable way of predicting who is most at risk of dying, and who might benefit most from surgery or other treatment. Now, a study published in the July 26 New England Journal of Medicine by an internatio...JCI table of contents -- July 26, 2007
... diphtheria toxin (DT). In healthy mice, injected, dying cells are normally selectively engulfed and destro...f the spleen, the ingestion and destruction of the dying cells by dendritic cells was irregular and the mice became susceptible to the development of a multi...Stem cell therapy rescues motor neurons in ALS model
...sin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease. The new work, conducted in a rat model and reported today (July 31) in the online, open-access journal from the Public...Genetic analysis finds greater threat in frog-killing fungus
...xt year, we'd come back to see hundreds of dead or dying frogs, and then the following year, they'd all be gone." Although genetic testing should be able to detect the spores, scientists do not know where to look for them. In addition, blindly testing environmental samples has thus far failed to yield ev...Indo-Pacific coral reefs disappearing more rapidly than expected
...orals in the central and western Pacific ocean are dying faster than previously thought, University of North Carolina at Chapel Hill researchers have found. Nearly 600 square miles of reef have disappeared per year since the late 1960s, twice the rate of rainforest loss. The reefs are disappearing at ...Study begins to reveal clues to the cause and progression of sepsis
...ease and stroke we knew that too many people were dying of cardiovascular disease, but we didnt know enough about the disease to effectively treat and prevent it, said Derek C. Angus, M.D., M.P.H., professor and vice chair of research, department of critical care medicine, University of Pittsburgh School ...