Tag: "dynamin" at biology news
JCI table of contents: August 1, 2007
...OGY: Protein leakage from the kidney controlled by dynamin
Many diseases of the kidney are characterized b...at destruction in the kidney of a protein known as dynamin
by cathepsin L causes proteinuria in a mouse model of kidney disease. Consistent with this, when mic...
Study revises dynamin's role in nerve cell function
...cience, suggests that a key cellular enzyme called dynamin
1 is not essential to all synaptic transmission, a...is not always necessary for this process. Instead, dynamin
1 goes into action only when the synapse enters moments of especially high activity. "In that sens...
News tips from the Journal of Neuroscience
...HA-DAT. Not surprisingly, clathrin heavy chain and dynamin
emerged from the screen as molecules critical for endocytosis. Knockdown of the ubiquitin ligase Nedd4-2 (neural precursor cell expressed, developmentally downregulated 4-2) also reduced endocytosis, consistent with the idea that PKC-induced DAT ubiq...
If the chemistry is right you might remember this
... to be the molecule that simultaneously works with dynamin
to allow the transmission of messages between nerv...communication shuts down. 'The partnership between dynamin
and syndapin is crucial for the continous cycle of neurotransmission. This makes syndpain a very spe...
Gene with broad role also causes prevalent, inherited nerve disorder
...or Human Genetics. A defect in the ubiquitous gene dynamin
2 underlies one form of the prevalent, familial ne...y of white blood cells, suggesting that defects in dynamin
2 might underlie both conditions, the researchers reported in the Jan. 30, 2005, issue of Nature Ge...