Tag: "dysfunction" at biology news

Retina adapts to light changes by rewiring itself

...normally works, you can then try to understand how dysfunction occurs."...

Cancer survivors may be at higher risk for cognitive dysfunction

...vivors. "This suggests that possibly the cognitive dysfunction gets worseover time with increased survival duration," Heflin said. The comparison with cancer-free twins means that the increaseddysfunction cannot be attributed to the normal aging process. The researchers also found a doubled risk of dementia in t...

ANU medical researcher wins national award

... of the largest health problems in the community - dysfunction of the immune system. Autoimmune diseases include type 1 diabetes, rheumatoid arthritis, systemic lupus and multiple sclerosis. "The research program is a clear example of how ANU leads Australian and international research by looking over the horizo...

New study demonstrated add-on effects of ACTOS (pioglitazone HCl)

... by targeting insulin resistance, a core metabolic dysfunction of type 2 diabetes. The multicenter, single-arm, 17-week, open-label study enrolled 305 people with type 2 diabetes taking statins (with or without other lipid-lowering drugs) along with Avandia alone or in combination with another oral anti-diabetic...

Viagra shows potential vasopressin-independent cGMP signaling in certain diabetes

...ales estimated at about $1 billion in the erectile dysfunction market. Administering Viagra to kidney cells showed a rapid rise in cGMP levels, not because more was being produced, but because less was being broken down. When tested in Brattleboro rats, which don't produce vasopressin, Viagra "mimicked the effec...

Molecular trigger for Huntington's disease found

...s mitochondrial genes and insofar as mitochondrial dysfunction appears important in HD, our findings provide a molecular mechanism linking disturbances of nuclei and mitochondria in HD." Download PDF...

Insulin spares intensive care patients from organ failure and death

...ation in these patients that is due to endothelial dysfunction which causes inadequate oxygen supply to the cellular systems. The endothelium controls vascular flow and trafficking of important biological molecules. The endothelium of patients with prolonged critical illness is protected by strict blood glucos...

JCI Table of contents August 1, 2005

...ation in these patients that is due to endothelial dysfunction which causes inadequate oxygen supply to the cellular systems. The endothelium controls vascular flow and trafficking of important biological molecules. The endothelium of patients with prolonged critical illness is protected by strict blood glucos...

Nerve cells' power plants caught in a traffic jam

...lace that is able to deal with minor mitochondrial dysfunction within the nerve. Besides providing energy, mitochondria carry out other tasks important for cell survival. One important mitochondrial task is taking up excess calcium. Calcium is the main ingredient for proper neuron function. Too much calcium can ...

Smoking gun for Alzheimer's disease

...d kills nerve cells in the brain, leading to brain dysfunction and ultimately death." There are currently more than 200, 000 people with Alzheimer's disease in Australia. The number will exceed 730, 000 by 2050. "Quinolinic acid is part of a biochemical pathway called the kynurenine pathway," said the lead autho...

Micro RNAs play role in egg making

...orthwestern. "It is intriguing to think that miRNA dysfunction might be at the root cause of certain forms of infertility. We already know that miRNAs are involved in cancer and stem cell biology." Investigators were initially surprised to find that miRNAs affected only a small fraction of expressed genes within...

$3.4 million directed to key UW-Madison MS study

...ng symptoms such as numbness, blindness, cognitive dysfunction and paralysis. An important part of the Wisconsin project, according to Duncan, will be efforts to direct human stem cells to become myelinating cells that could be used in transplants to repair the nervous system lesions characteristic of multiple s...

Malfunctioning bone marrow cells sabotage nerve cells in diabetes

...g from bone marrow caused premature cell death and dysfunction when they merged with neurons, resulting in neuropathy," said Chan. "It all began several years ago, when we were developing gene therapy to cure diabetes in mice. By chance, we observed insulin-producing bone marrow cells outside the pancreas, and...

Acupuncture versus acid reflux: 40% cut in sphincter relaxations brings hope for relief

...unction. Thus reflux disease occurs because of LES dysfunction and, in many patients, the additional effects of a hiatus hernia," Holloway said. As for H. pylori, in a fact sheet on heartburn, HH and GERD, NIDDK includes these poignant observations: "Much research is needed into the role of the bacterium Helic...

Designed peptides: Candidates for the treatment of cancer, sexual dysfunction, eating disorders

...ng disorders (anorexia, obesity), diabetes, sexual dysfunction and skin cancer. Victor Hruby, who is a Regents' Professor at the department of chemistry in UA's College of Science and a member of the Drug Discovery Initiative at UA's BIO5 Institute, will talk about the biological roles of peptide hormones and p...

High doses of vitamin E boost rat survival rate 40%; brain function, neuromuscular gains

...upplementation," it added. Clues to mitochondrial dysfunction -- and next steps Finally, the authors noted two...d energy supply are the basis of the mitochondrial dysfunction in aging and that mitochondrial dysfunction is the pacemaker of the decline in neurological performa...

Researchers gain support from Merck Sharp & Dohme for novel area of diabetes research

...bly developing a cure for diabetes since beta-cell dysfunction is a major factor contributing to the development of this disease. The three-year programme will award a total of 1,400,000 for outstanding research in diabetes. A number of grants of up to 100,000 each have already been awarded and these will be an...

JCI table of contents October 1, 2005

...Thus, intestinal epithelial MLCK-dependent barrier dysfunction is required for T cell activation-induced diarrhea...strate the mechanisms and critical role of barrier dysfunction in diarrheal disease. This work also identifies epithelial MLCK is a critical intermediate in intest...

FSU biologists describe key role of signal-transcribing gene during cell cycle

...We believe the specific cell-to-cell signaling and dysfunction observed in fruit flies is applicable to mammals, which also possess genes Notch and Cut," said Deng. The researchers traced the journey of transmissions originating from Notch which carries information gleaned from other cells following the signal...

Insect pheromone research wins Eppendorf/Science prize

...el normal cognitive function, as well as cognitive dysfunction associated with various inherited diseases. In 2003, he started his own lab at The Hospital for Sick Children in Toronto. A focus in his lab is on understanding how enduring, or remote, memories are organized in the brain. Johanna Montgomery, for he...

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(Date:10/15/2014)... Lithuania , Oct. 15, 2014   ... technologies, today announced the availability of the ... VeriLook Surveillance 3.0 provides real-time biometric face identification ... high-resolution digital surveillance cameras. The new version not ... and differentiates people from objects while they are ...
(Date:10/14/2014)... Research shows SIRT6—a protein known to inhibit the ... of skin cancers by turning on an enzyme that ... , Previously considered protective, SIRT6 is part of a ... genomic stability and prevent some of the genetic flaws ... can lead to cancer. This study, in the journal,s ...
(Date:10/14/2014)... N.Y. – Scientists have sequenced the house fly genome ... one might expect from an insect that thrives in ... published Oct. 14 in the journal Genome Biology ... biology and of how flies quickly adapt to resist ... Adult house flies (Musca domestica) carry and transmit more ...
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