UCI awarded $3.5 million for stem cell research
...x UCI projects with focuses ranging from muscular dystrophy to mitochondria were selected by the Independent Citizens Oversight Committee (ICOC) for two-year Scientific Excellence through Exploration and Development (SEED) grants. CIRM support of UCI faculty underscores the strength of stem cell research i...JCI table of contents -- March 22, 2007
...N: Inflammatory pathway leads to Duchenne muscular dystrophy Duchenne muscular dystrophy (DMD) is characterized by progressive muscle wasting and usually results in death by the age of 30. ...New therapeutic insight into duchenne muscular dystrophy
... Duchenne muscular dystrophy. Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy, affecting about 1 in 3000 males each year. It is an X-linked recessive disease, in which mutations in the dystrophin gene causes progressive and degenerative muscle weakness. DMD is generally leth...Switching genes to overdrive improves muscular dystrophy symptoms in mice
...y of Iowa College of Medicine. Duchenne muscular dystrophy (DMD) is the most common type of muscular dystrophy in children, occurring once in about every 5,000 live births of boys, and is ultimately fatal. The a...The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better
...ab while searching for a cure for Duchene muscular dystrophy (DMD). DMD is a genetic disease estimated to affect one in every 3,500 boys. Patients with DMD lack dystrophin, a protein that gives muscle cells structure. Using an animal model of the disease, his laboratory is using stem cells to deliver dystrophi...JCI table of contents -- April 19, 2007
... heart function defects in Emery-Dreifuss muscular dystrophy Emery-Dreifuss muscular dystrophy (EDMD) is characterized mainly by defects in heart and muscle function and is caused by mutations in...First demonstration of muscle restoration in an animal model of Duchenne muscular dystrophy
...e function in a mouse model of Duchenne's muscular dystrophy (DMD). The research appears ahead of print in an advanced online publication of Nature. "This new class of treatment has the potential to help a large number of patients with different genetic diseases that have the same type of mutation," says sen...New clues for treatment of disease that causes accelerated aging
...re prevalent disorders including forms of muscular dystrophy and heart disease. In addition, recent studies by other labs have shown that occasional errors in the production of lamin A may take place even in people with "normal" copies of the gene. Scientists suspect that accumulation of these bad copies may c...UVa researcher studying disease that cripples newborns
...o learn their child has type 1 congenital myotonic dystrophy (CDM1), a progressive and crippling genetic disord..., mothers dont know that they have type 1 myotonic dystrophy (DM1) a common form of muscular dystrophy because they have mild symptoms or none at all, notes Ma...A fly lamin gene is both like and unlike human genes
... called laminopathies, including forms of muscular dystrophy and premature aging diseases. The fruit fly Drosophila melanogaster has 2 lamin genes that are expressed in A- and B-type patterns, and it has been assumed that similarly expressed lamins perform similar functions. Yet, Dushay and his colleagues, ...New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
...he Emory University School of Medicine. Muscular dystrophy includes more than 30 genetic diseases characteriz...appear until middle age or later.Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy and primarily affects boys. It is caused by abs...Faulty cell membrane repair causes heart disease
...r by inherent muscle weakness caused by a muscular dystrophy defect. The results are published in the July 1 is...low cardiac and skeletal muscle damage in muscular dystrophy patients," said Campbell who also holds the Roy J. Carver Biomedical Research Chair in Molecular Phy...Penn researchers discover pathway that eliminates genetic defects in red blood cells
...kes a protein that is too short. Duchenes muscular dystrophy and cystic fibrosis are examples of hereditary diseases that result from nonsense mutations. We describe a surveillance pathway that targets RNA that is only found in red blood cells, says senior author Stephen A. Liebhaber, MD, Professor of Genet...