Nanotechnology may find disease before it starts
...nology may one day help physicians detect the very earliest stages of serious diseases like cancer, a new stud...dentify disease at its cellular level, at its very earliest stage." The study is in the current issue of the journal Physics in Medicine and Biology. The resear...DNA conclusive yet still controversial, Carnegie Mellon professor says
...d the use of DNA evidence, Roeder said. One of the earliest controversies to erupt over DNA testing was the magnitude of genetic diversity among people of different ancestry. Some controversy remains concerning the so-called "cold hit" technique, in which investigators search a DNA database to find a match o...Celgene founder Sol J. Barer to receive 2006 Winthrop-Sears Award
...d. The award is named in honor of two of America's earliest chemical entrepreneurs, John Winthrop, Jr., and John Sears. Previous recipients of the Winthrop-Sears Award include renowned industry figures such as Robert L. Gore, Jon M. Huntsman, Ralph Landau, James Mack, George Rosenkranz, Harold A. Sorgenti, an...Study provides first look at the 'birth' of a retina cell
...). In PNAS, Swaroop's team reports that NRL is the earliest marker of rod precursors, or cells that are fated ...n cone -- development. "This model may give us the earliest look yet at some devastating diseases we are all eager to cure," he says....UCSF Institute for Regeneration Medicine receives gift from Dolbys
... goal of answering fundamental questions about the earliest steps of embryo and cell development. "Insights into these processes will help lay the groundwork for controlling cell differentiation and exploring the possibility of regenerating tissues destroyed by diseases and traumatic injuries," he said. Expan...Massive duplication of genes may solve Darwin's 'abominable mystery' about flowering plants
...t suggests a whole-genome duplication event in the earliest flowering plants," he says. "A polyploidy event early in the history of flowering plants could explain their sudden evolution." One unexpected observation from the study is the relatively slow accumulation of mutations in primitive flowering plant...Methane-belching bugs inspire a new theory of the origin of life on Earth
... appears to be the direct descendant of one of the earliest true microbes. "We know that this bug is very ancient indeed," Ferry told the Penn State Astrobiology Research Center's annual meeting earlier this week. "There is strong phylogenetic evidence that acetate kinase is a very ancient enzyme." No such ev......17 species of leafy shrubs and trees, is where the earliest cactus lineages began. Using field studies and environmental modeling, Edwards and Donoghue found that the Pereskia species already showed water use patterns that are similar to the leafless, stem-succulent cacti. "[Our] analyses suggest that several...Exxon Valdez oil found in tidal feeding grounds of ducks, sea otters
...of shoreline on northern Knight Island, one of the earliest and worst affected areas during the spill. They found Exxon Valdez oil at 14 of the 32 sites. Although oil was spread throughout the tidal range, about half of it was found in the low tide zone, where predators could encounter it while searching for ...Genetic tug of war determines sexual differentiation
...sform either into a testis or an ovary. During the earliest stages of development, both XX and XY gonads are characterized by similar patterns of Sox9, Fgf9 and Wnt4 expression. "If the Sry gene is not expressed at a critical point in development, Sox9 and Fgf9 genes turn off, and the gonad develops along the...Origen publishes in Nature a robust and versatile method for creating transgenic chickens
...very useful new tool for understanding some of the earliest and most fundamental events in developmental biology on a molecular level," said Robert J. Etches, Ph.D., D.Sc., vice president of research at Origen Therapeutics. "This work addresses a major biomedical issue -- how to produce antibody-based medici...Single copy of Parkinson's-risk gene mutation may lead to earlier symptom onset
... genetic screens were done on the patient with the earliest onset of symptoms. If that patient was found to have parkin mutations, genetic screens were completed on other affected family members. Parkin mutations were found in 23 (12.6 percent) of the 183 screened families. Among the families with parkin m...Parkinson's disease mechanism discovered
... so they could determine which abnormalities arose earliest in the pathological process. Those experiments by Cooper revealed that an important early defect affected the machinery that transports proteins between two major cellular organelles -- the endoplasmic reticulum (ER) and the Golgi apparatus. The endo...Key to early diagnosis of autism may be in the placenta
...ne have discovered in the placenta what may be the earliest marker for autism, possibly helping physicians dia...ses, onset is early in infancy. Information on the earliest development aspects of autism in children has been limited even though approximately one in every 20...A probable cause for Parkinson's?
...d, or biomarker, that could be used to predict the earliest stages of brain impairment. Many biomedical researchers believe that detecting disease states before symptoms occur is the key to reversing many as-yet-incurable diseases. The biomarker is known as nitrotyrosine, made when an amino acid in the brai...Genetic parallels found between lung development and lung cancer
...ssion pattern resembles gene expression during the earliest stages of lung development have the worst prognosi...common genetic features with the cerebellum in its earliest stages of development ( www.childrenshospital.org/newsroom/Site1339/mainpageS1339P1sublevel81.html )...Researchers aim to cut future need for liver transplants
...ed primitive liver cells possibly dormant from the earliest developmental stage of a human being which have the potential to mature into different cells types and help repair a failing liver. Their newly-published findings could pave the way for alternative treatments using cell replacements instead of organ...Researchers get closer to preventing Alzheimer's disease
...the brain (the main characteristic of AD). In the earliest stages of Alzheimer's, beta-amyloid peptides are o...eta-amyloid peptides accumulation, starting in the earliest stages of AD. ...Making a face: A new and earlier marker of neural crest development
...ion and prove that its function is required in the earliest stages of development. The neural crest is a pop...after "stage 10," the researchers were seeking the earliest conditions surrounding formation of these important stem cells. "Understanding the origin of neura......-celled ancestor. This project targets ten of the earliest branches of animals and fungi along with some of their single-celled relatives providing, for the first time, comprehensive data to fill gaps in our understanding of animal and fungal evolution. Recent research has shown that some genes in the human ...