Penn receives grant for initiative to help understand genes' effects on medications
...acoepidemiology, with a particular interest in the effects and proper use of drugs and devices for patients with coronary artery disease. This release can also be found at: www.uphs.upenn.edu/news...Amgen investigational therapy, AMG 162, increased bone mineral density with twice yearly injection
...tively enroll and initiate our pivotal trial." The effects of AMG 162 (at 60 mg twice yearly) at the total hi...otein called osteoprotegerin (OPG) to modulate the effects of excess RANK Ligand. OPG acts as a decoy receptor, preventing RANK Ligand from binding to its rec...Endangered frogs coexist with fungus once thought fatal
... stable infections of this fungus. To evaluate the effects of the fungus on frogs in their natural habitat, the authors focused on six species living in the high-elevation rainforest streams of Eungella National Park in Queensland, Australia, where frog losses were "particularly catastrophic". Two species va...A treatment, not a cure: Calcium silicate neutralizes an acidic stream
...he paper is the first to document the neutralizing effects of Wollastonite, a calcium silicate, on an acidic ...ural source of calcium carbonate. Its neutralizing effects are short-lived, however, and can generate extreme fluctuations in water chemistry. Recognizing the ...Stanford cooling tool may improve performance of athletes, soldiers
...g, where the time to exhaustion is very short, the effects on exercise performance were dramatic. "We helped a weight-lifter increase his capacity to do pull-ups from 180 to 600 in the same time period after six weeks of training," notes Grahn. "And we've seen professional football players triple their anaer...Running not swimming or biking is best kind of loading exercise for childrens bone growth
...ing bones are most responsive to the strengthening effects of running/jumping, which have the additional bene...protocols that insert 'rest' periods to reduce the effects of desensitization can double anabolic responses to mechanical loading," he adds. Again, it's unclea...Putting physiology into the Nobel Prize: 2004 marks 100th anniversary of Pavlov's award
...tory neural center, and, therefore, their combined effects were expressed in vagal efferent output and glandular secretion." In the eighth and last in a series of lectures that overcame the Nobel committee's objection to his lack of publication, Pavlov was "primarily concerned with the relationship between p...Is Interleukin-6 the 'holy grail' of exercise mediation?
...nduced factor, which mediates some of the exercise effects in other tissues and organs such as the liver and ...ti-inflammatory effects. It is this combination of effects that has prompted such widespread study....New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...ic and proteomic techniques may help determine the effects of aerobic exercise and weight gain on muscle gene and protein expression patterns," Hittel said. They found that adenylate kinase 1 (AK1), an important enzyme in regulation of cellular energy metabolism, particularly skeletal muscle, was ...Researchers find chemosignal that encourages women's sexual desire
...lly, such a study would also demonstrate how these effects would have increased the evolutionary fitness of individuals who used this system of social communication during human evolution," McClintock explained. Other research suggests that women living in early societies produced children when food...Bugs in the gut could play key role in understanding human disease and drug toxicity
...gut and the immune response, all of which can have effects on the effectiveness of drugs." The researchers believe it will be possible to develop a model for testing the body's response to disease, looking at how the microbes in the gut interact with each other, mammalian genes and other environmental factor...The PSA bounce Does it have clinical significance?
... situation, but hormones can have significant side effects for the patient, and may not be clinically necessary. For these reasons, it's important to develop clear guidelines." In this retrospective analysis, data were gathered from the records of 4,839 men treated only with external-beam radiation between...Toward a better understanding of taste and smell impairments
...es to avoid or overcome the sometimes debilitating effects of chemosensory dysfunction. Approximately si...ortant resource for predicting and alleviating the effects of occupational chemical exposure on sensory function related to taste and smell. Related studies wi...Society for Psychophysiology Research
...m memory. These findings document the detrimental effects of cocaine use on cognitive function and clarify the mechanism by which cocaine adversely affects the brain. SENSATION SEEKING INFLUENCES ON ATTENTION, AROUSAL, AND MEMORY JUDGMENTS ABOUT "ACTION NEWS" TELEVISION NEWS STORIES Fox, Julia R., Indian...Experts present new research on hot topics in aging at GSA's annual meeting in Washington, DC
...ntion improved the targeted cognitive ability, and effects were durable to two years. No training effects on daily function were detected at 2 years, likely because of minimal functional decline across all ...Sedentary overweight people get insulin boost from short term exercise; CVD risks trend down
...lin action following short-term exercise training: effects of exercise or energy balance?" while Mitchell will present "The effects of short-term exercise, in negative or zero energy balance, on CVD risk factors." Editors note: M...Environmental exposures before and after birth can harm children's lungs
...ildren for several years after delivery to examine effects of environmental pollutants. The researchers meas... old. These findings may suggest that the harmful effects on the lung develop after prolonged or later exposure to ETS. "At this point we can only specul...Support groups aid women with 'breast cancer gene mutations'
...ts. In the first prospective study to evaluate the effects of a psychosocial intervention for women carrying BRCA1 or 2 mutations, Mary Jane Esplen, Ph.D. of the University Health Network and the University of Toronto and her colleagues followed 70 women who participated in 12 group sessions of "supportive-e...Acoustics meeting in San Diego
...ill give a tutorial lecture on ocean noise and its effects on marine mammals, a subject that many ASA members are vigorously investigating. D'Spain and Wartzok will present the scientific issues pertaining to this subject. They will discuss basic physics of sound in the ocean as well as long-term trends of ......mulate aneurysm formation, scientists compared the effects on the transplanted aortas. All male aortas transp...to elastase perfusion, the scientists compared the effects on aortas from each group. All the male rats developed aneurysms, but the estradiol-treated rats had...