Heart responds to fasting by remodeling vital energy-producing components
...in the membranes make the mitochondria more energy efficient and serve as an adaptation to nutritional deprivation in mammals," says Richard Gross, M.D., Ph.D., senior author and professor of medicine and director of the Division of Bioorganic Chemistry and Molecular Pharmacology in the Department of Medicine....Visualizing the end of the human genome
...omeric DNA containing at least ten nucleotides for efficient recognition and binding of DNA. "We were confused about how ten nucleotides was even a binding site, because it wasn't a multiple of six." Cech said. "If you need to coat something that has a repeating motif of six, you need to bind some multiple of ...Brain surface stimulation alleviates Parkinson's symptoms
...termine whether motor cortex stimulation can be as efficient as direct stimulation of the deep-brain regions of the striatum, "the results obtained here in baboons strongly suggest that this may be the case." Xavier Drouot, Satoru Oshino, Bechir Jarraya, Laurent Besret, Haruhiko Kishima, Philippe Remy, Julien...Efforts to clone primates move forward
...es. "What this shows is that the Korean method for efficient human somatic cell nuclear transfer is equally effective for nonhuman primates, allowing the further progress toward development of an animal model which parallels human biology," said Dr. Schatten. "This approach does not violate federal or state la...NIH provides $32.8 million to enhance biomedical informatics research network
...e available to help new collaborative efforts make efficient use of this infrastructure at an increasingly rapid pace. These tools and best practices are intended to maximize the extent to which the infrastructure being developed can quickly be deployed to support the greater biomedical research community....Canola study solves seed oil mystery
...ding to the MSU team, is that plant seeds are more efficient than anyone thought. "Seeds achieve this high ...observed an enzyme called Rubisco providing a more efficient pathway to convert sugar to carbon chains for oil. And the pathway involved lots less coughing up of...New model of rare childhood blindness holds promise for testing preventive therapies
... "The mouse model is an efficient tool for gaining insights into both normal and abnormal development of the retina," said Stacy Donovan, Ph.D., co-author of the paper and a postdoctoral student in Dyer's laboratory. To produce the mouse model of LCA, the researcher...Microbe's genome reveals insights into ocean ecology
...ompounds for biosynthetic processes allowing more efficient use of organic carbon in an environment that has little to go around. "The microbe's predicted ability to use such inorganic compounds was surprising," says Ward. "This study demonstrates how genome analysis allows us to propose new hypot...NSF funds Panikov's Alaskan Tundra Microbial Observatory project
... ultracold temperatures, and development of highly efficient biocatalysts functioning at below freezing temperatures....Immune system contributes to evolution of a new fluorescent protein
Fascinated by the efficient way the human immune system generates a rapid response to create a near-infinite variety of antibodies, researchers have "hijacked" that machinery and used it to evolve a new type of fluorescent protein. The mutation process, called somatic hypermuta...Inexpensive, mass-produced genes at core of synthetic biology advances at UH
...synthesis of genes economical, we can provide more efficient tools to aid the efforts of researchers to understand the molecular mechanisms that regulate biological systems. There are many potential biochemical and biomedical applications." Most immediately, examples include understanding the regulation of ...Scientists identify molecular events that drive cell senescence
...tions show that ASF1a promotes and is required for efficient senescence-associated cell cycle exit and support the notion that HIRA/ASF1a-mediated formation of SAHF directly contributes to cell cycle exit during senescence," concludes Dr. Adams. The researchers speculate that alterations of HIRA and ASF1a migh...Genome comparison of four campylobacter strains yields new genetic markers and clues to virulence
...en skin and was found by the USDA-ARS lab to be an efficient colonizer of chicken digestive tracts. The PLoS study also compared the two C. jejuni genomes to the not-quite-complete DNA sequences of a multidrug-resistant C. coli strain isolated from a chicken; a C. lari strain (clinical isolate) associat...Bone specialists' hi-tech answer to patient care
...resources for these rare conditions. "By providing efficient access to a pan-European network of experts and genetic-testing facilities, doctors can make accurate diagnoses enabling patients to receive the best treatment for their particular condition. "The system is completely novel and the successful deliver...Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2005
...components that are lighter in weight, more energy efficient and have an extended use life may be possible through a technology that can alter the characteristics of steel and other materials. Researchers at the Department of Energy's Oak Ridge National Laboratory and Florida State University are studying a m...Satellite data to track wildlife: Elephants in space
...ave been a primary tool, but they are not the most efficient when dealing with large animals and animals in remote locations. The WCS's recent use of satellite technology, sponsored by NASA, may revolutionize the way endangered wildlife in remote areas of the world are counted and monitored. Using cameras fixe...Key molecule in plant photo-protection identified
...otosynthesis, the dream of solar power as a clean, efficient and sustainable source of energy for humanity could be realized. A potential pitfall for any sunlight-harvesting system is that if the system becomes overloaded with absorbed energy, it will likely suffer some form of damage. Plants solve this proble...DNA molecules used to assemble nanoparticles
...Michigan researchers have developed a faster, more efficient way to produce a wide variety of nanoparticle drug delivery systems, using DNA molecules to bind the particles together. Nanometer-scaled dendrimers can be assembled in many configurations by using attached lengths of single-stranded DNA molecules, w...Plant protein mimics hormone that mitigates diabetes and obesity
...ressan said. Running a screen in yeast is a highly efficient first step in looking for potentially therapeutic agents because yeast is easy to grow and is very well understood at the cellular and molecular genetic levels. "It may be possible to expose different drug candidates to the receptor in yeast that rec...University of Arizona receives IBM grant for massive virtual storage system for life sciences data
... storage infrastructure that will give researchers efficient access and ability to manage vast amounts of biological data. "It is a wonderful opportunity to team with IBM in implementing leading-edge technology," said Michael Cusanovich, director of ARL and professor of biochemistry and molecular biophysics. R...