News tips from the Journal of Neuroscience
...receptors. 3. Sensorimotor Integration in C. elegans Christopher V. Gabel, Harrison Gabel, Dmitri Pavlichin, Albert Kao, Damon A. Clark, and Aravinthan D. T. Samuel This week, Gabel et al. show that worms have a good understanding of high school physics even without reading the textbook. The authors ...Left-right wiring determined by neural communication in the embryonic worm
... aren't so different: The roundworm Caenorhabditis elegans has nerves on its left and right sides that perfor... the worm develops. Every neuron in the adult C. elegans has been mapped and named. Handedness researchers are particularly interested in two olfactory neuro...Executable biology -- Computer science sheds light on animal development
...s journal PLoS Computational Biology. During C. elegans development, uncommitted precursor cells different...le laboratory data, they found that the fate of C. elegans vulval precursor cells depends upon the time-sequence of two cellular signaling pathways, as well as...Berkeley Lab Life Sciences division awarded NIH grants for fruit fly, nematode studies
...d gene expression." Research on the nematode C. elegans is represented by a modENCODE project for which Ab...e "functional landscape" of D. melanogaster and C. elegans "should aid our efforts to tackle such questions in humans." Elise Feingold, NHGRI program direct...Fly and worm models to teach researchers about human biology and medicine
...D HUTCHINSON CANCER RESEARCH CENTER, SEATTLE-- "C. elegans and D. melanogaster". "Genome-Wide Profiling of HistoneVariants in Drosophila and Caenorhabditis" -- First-year funds,$429,000; total funds, $1.7 million. GARY KARPEN, PH.D., LAWRENCE BERKELEY NATIONAL LABORATORY, UNIVERSITY OFCALIFORNIA AT BERKELEY....NYU's Center for Comparative Functional Genomics part of $57 million MOD-ENCODE consortium
...isms (MOD) fruit fly and round worm Caenorhabditis elegans (C. elegans) as models to understand the functiona...a specific part of the genome of the round worm C. elegans called the 3UTR. 3UTR is a section of all animal genomes where special regulatory genes called micro......eloping embryo of the nematode worm Caenorhabditis elegans undergoes its first cell division. The division gives rise to a bigger cell at the anterior end of the embryo, where the head will develop, and a smaller cell at the posterior end. For this asymmetric division to take place, the mitotic spindle, the ...Salk researchers discover first gene that specifically links calorie restriction to longevity
...signaling pathways in the roundworm Caenorhabditis elegans (C. elegans), but experiments by graduate student Siler Panowski in Dillins lab suggested otherwise. In the worm, signals passed down the insulin/IGF-1 pathway regulate a DNA-binding protein called DAF-16 that belongs to what is called the forkhead...Researchers find level of special protein is critical to proper formation of muscles
...y, done using worms of the species Caenorhabiditis elegans (also known as C. elegans), showed that an over-su...on." Epstein's group made the discovery using C. elegans worms genetically engineered to produce more UNC-45 than do normal worms. (C. elegans is often emplo...A 'traffic light' for neurons means 'go' for improving brain research
...in Germany were able to cause tiny worms called C. elegans to stop swimming while their genetically altered motor neurons were exposed to pulses of yellow light focused through a microscope. In some experiments, exposure to blue light caused the worms to wiggle in ways they weren't moving while unperturbed. ......re based on studies of the nematode (roundworm) C. elegans and studies of mouse embryonic stem cells. The C. elegans studies were carried out in collaboration with another of BRICs research groups, led by Associate Pr...Worms produce surprise insight into human fever
...s about 70 trillion cells. An adult Caenorhabditis elegans roundworm has exactly 959 cells. Yet we have an... dissecting two conserved pathways required for C. elegans immunity to bacteria, Aballay found a wealth of data on innate immunity plus a surprising insight in...CU-Boulder space station experiments to involve K-12 students around the globe
...nts will focus on a group of nematodes known as C. elegans that will ride on the space station, with students...out a week, he said. The orbit duration of the C. elegans experiment will be more than 10 times longer than any previous nematode experiment in space. We an......ey family of genes and proteins that help bring C. elegans chromosomes together during meiosis. This speciali...d their colleagues identified the function of a C. elegans protein called HIM-8. This protein binds to and helps bring together copies of the worm's sex chromo...NYU, Scripps finding offers new path for treatment of diabetes
...ment of Cell Biology, used the worm Caenorhabditis elegans (C. elegans) to identify a new therapeutic target protein for diabetic treatment. C. elegans is the first animal species where RNA interference (RNAi) is discovered and thus, an excellent model...Gene sequencing center to receive $156 million
... technology that would allow us to sequence the C. elegans genome in two or three days at a cost of $5,000. We are continually working to produce sequences faster, better and less expensively." The other two sequencing centers funded by the new grant are located at Baylor College of Medicine and the Broad I...Tiny worm provides model for the genetics of nicotine dependence
ANN ARBOR, Mich.---The unassuming C. elegans nematode worm, a 1-millimeter workhorse of the gen...ed a series of experiments which establish that C. elegans can get hooked on nicotine. Like humans, the nicotine-sensitive worms showed acute responses to nico...Study reveals mechanism for cancer-drug resistance
...LLAS Oct. 9, 2006 Using the worm Caenorhabditis elegans , researchers at UT Southwestern Medical Center ha...in, so they worked with the tiny research worm C. elegans , which is often used for genetic studies but not often used to test drugs. The researchers create...CSH Protocols publishes cutting-edge methods for analyzing complex molecular interactions
...s to which proteins bind in the model organism C. elegans (the "worm" used in many developmental studies). Because it relies on basic molecular biology techniques, this method will also be useful for analyzing the intricately coordinated patterns of gene regulation in other species. Another technical cha...American Andrew Z. Fire shares Nobel Prize for discovering RNAi
... egg of the tiny soil-dwelling worm Caenorhabditis elegans changes from one cell to over 500, neatly arranged...to conduct research on the nematode Caenorhabditis elegans at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England, under the gui...