Tag: "elevated" at biology news

Study finds no association between diet and pancreatic cancer among men and women

... glycemic load and dietary sugar are related to an elevated risk of pancreatic cancer among women. More research needs to be done to examine individual dietary factors. Prevention is a priority in such a highly fatal disease. Both smoking and obesity increase pancreatic cancer risk and should be considered...

JCI table of contents May 1, 2005

...ns in 2 genes called WNK1 and WNK4. Patients have elevated blood pressure and high levels of potassium in their blood. In a study appearing online on April 7 in advance of the print publication of the May 1 issue of the Journal of Clinical Investigation, David Ellis and colleagues from Oregon Health and Scie...

Gene mutated in cancer found in some with autism

...or other syndromes involving PTEN mutations and an elevated risk of cancer." PTEN is a tumor-suppressor gene, and normally helps prevent cells from becoming cancerous. When a mutation silences tumor-suppressor genes, it can place a person at higher-than-usual risk of developing cancer during his or her lifet...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

...arcinoma. NASH is one of the most common causes of elevated aminotransfereases in patients referred for evaluation to hepatologists. Obesity and type-2 diabetes are associated to NASH. Since the prevalence of these diseases is increasing, the prevalence of NASH is also expected to increase and therefore, thi...

Mouse with designer liver has enhanced glucose tolerance and improved insulin response

...lls. Upon stimulation with insulin, they found an elevated level of Akt/PkB kinase, an enzyme needed for insulin signaling, and elevated activity of IRS proteins. There was no activation of another enzyme, Erk, which is elevated in norma...

JBC study shows that bigger isn't necessarily better for amyloid proteins

...roteins, and not the monomeric or fibrillar forms, elevated intracellular calcium levels. The oligomers also caused rapid cellular leakage of fluorescent dyes, suggesting that these molecules cause a generalized increase in membrane permeability. "Membrane impermeability is fundamental to life," explains Dr....

Low oxygen likely made 'Great Dying' worse, greatly delayed recovery

...history some 251 million years ago was preceded by elevated extinction rates before the main event and was fol...ygen levels was likely a major reason for both the elevated extinction rates and the very slow recovery. Earth's land at the time was still massed in a superco...

JCI table of contents May 1, 2005

...owth Increased adipose mass is associated with an elevated risk of breast cancer, but little was known about how fat cells actually contribute to carcinogenesis. In a study appearing online on April 14 in advance of the print publication of the May issue of the Journal of Clinical Investigation, Philipp Sche...

A big fat contribution to breast tumor growth

Increased adipose mass is associated with an elevated risk of breast cancer, but little was known about how fat cells actually contribute to carcinogenesis. In a study appearing online on April 14 in advance of the print publication of the May issue of the Journal of Clinical Investigation , Philipp Sc...

Other highlights in the April 20 JNCI

...tes of human papillomavirus (HPV) infection and an elevated risk of developing cervical cancer. However, information is lacking regarding several fundamental aspects of the association between HIV and HPV infections. A new study has found that, in women with HIV, the combination of plasma HIV RNA level and CD...

Reducing specific gene levels makes breast cancer cells more responsive to ionizing radiation

...ein. Almost all invasive breast cancer cells have elevated BRCC36 levels compared to normal breast milk-duct cells. "Since BRCC36 directly affects BRCA1 and BRCA1 is activated after exposure to radiation, we wanted to see if BRCC36 might be important in this response," said Xiaowei Chen, Ph.D., a Fox Chase p...

Royal Society study on adaptability of fish to warming oceans

...e thermal specialization paradigm: compensation to elevated temperatures in Antarctic fish by Dr F Seebacher, ...fish compensate for the initial negative impact of elevated temperatures and regain their original performance levels despite being several degrees warmer. Thes...

Variation in immune response gene causes age-related macular degeneration when triggered

...the vaccination rate is highest also experience an elevated rate of AMD," said Dr. Allikmets. The researchers continue to conduct new studies based on their results to further understand the triggers for this gene. "This is an area for epidemiologists to study, but as our research progresses we should event...

JCI table of contents May 2, 2005

...reased angiogenic activity. The latter was due to elevated levels of proteins called chemokines, namely CXC chemokines. Blocking CXC chemokine action by inhibiting receptor interactions was beneficial in mice and reduced BOS. In an accompanying commentary, Ivor Douglas and Mark Nicolls write that this stu...

Researchers observe predictors of natural immunity to ovarian cancer

...s were among seven events or conditions leading to elevated levels of these antibodies. The list includes mas...n the bud. Furthermore, multiple events leading to elevated MUC1 antibodies resulted in correspondingly higher reductions in ovarian cancer risk. Women who exp...

The fat connection

...tion of the beta cells may be tied to persistently elevated insulin levels, hastening the onset of the disease. How does this destructive cycle begin? To understand GPR40's role, Prof. Michael Walker and students Nir Rubins and Reut Bartoov-Shifman of the Weizmann Institute's Biological Chemistry Department t...

Polymer expert writes text about better, inexpensive ways to create plastic

...ain properties of plastic parts while remaining at elevated temperatures." Working chemists and engineers view this text as an excellent consumer's guide. Listed information includes not only data about the chemical properties of the filler--when applicable its density, moisture and thermal properties--but a...

Scientists journey to southern Africa to unravel the secret world of elephant communication

... construction of the campsite, which included four elevated tents, a cooking/dining area and a 20-foot-tall, two-story observation tower with a commanding view of the waterhole and surrounding scrubland. Sitting in the upper level of the tower, O'Connell-Rodwell and Katie Eckert pay close attention to the wil...

Natural relaxant protects against asthma, may yield new therapy

...ne (GSNO), that helps keep airways open. Mice with elevated levels of GSNO were much less susceptible than nor...the exhaled breath of patients with asthma showing elevated levels of NO, Stamler said. However, studies in which researchers have manipulated NO levels in mice...

Loyola researchers discover congestive heart failure biological marker

...normal heart. Yet, RCMP patients had significantly elevated BNP levels compared to CP patients. "The reason for this is because CP patients have a rigid or scarred pericardium the sac-like membrane covering the heart," said Leya. "As a result, the chambers of the heart are "restrained," and cannot expand and...

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(Date:10/19/2014)... access in India over the last 30 years ... emissions growth during that time, according to a ... Climate Change ., "Energy access is fundamental to ... life, including education, communication, and health," says IIASA ... While increased energy access is widely agreed to ...
(Date:10/18/2014)... patients referred for evaluation of suspected genetic conditions, ... 25 percent, including detection of a number of ... disease, according to a study appearing in ... coincide with the American Society of Human Genetics ... or coding regions of thousands of genes simultaneously ...
(Date:10/17/2014)... – Accurate knowledge regarding Ebola is critical and pertinent ... of hazardous global outbreak and epidemic. The Journal, ... a special issue, Ebola Virus and Public Health, to ... knowledge in this critical societal moment. , On ... Ebola for Clinicians . The primer was prepared by ...
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