Future diabetes drugs may target new protein interaction
... no one knew exactly how it was controlled or what else it might need in order to launch the sugar-making process. Sirtuin1, like its sirtuin relatives, is best known for removing molecular "decorations" on proteins that help organize DNA and restrict access to genes. It turns out that sirtuin1 also remov...New class of tuberculosis-fighting antibiotics suggested by biochemical-pathway study
... first enzyme in the chain, you inhibit everything else downstream and eventually the bacteria die," he explains. The research group tested phenothiazine, a drug used in the past to treat schizophrenia, in cultures of Mycobacterium tuberculosis, the bacterium that causes TB. They found that phenothiazine...Using molecular technique, researcher identify hospital pool bacterial pathogen
... he said. "There were no reported cases of anyone else becoming ill from exposure, and the pool would have been safe for healthy people, as long as they were not in the environment for long stretches of time." Angenent said he has results from a related study that shows air filters he and his cow...Leptin: A 'missing link' between obesity and diabetes?
...up with the sugar," says Myers. "There's something else contributing. Now the challenge is to find out what that is." He notes that the study will continue in mice, because of the difficulty in studying brain-body cell signaling in humans -- which would require a brain biopsy. But building a better unders...Mitsubishi offsets carbon footprint through investment in Madagascar's rain forest
...nus") of plants and animals that are found nowhere else on earth. Each biodiversity hotspot has already lost over 70 percent of original habitat, and the remainder faces imminent threat of further destruction. Madagascar, for example, has lost as much as 90 percent of its original forest cover. "Through......er. More than half its lemurs, none found anywhere else in the world, are threatened with extinction. Without immediate steps to protect these unique creatures and their habitat, we will lose more of our planet's natural heritage forever." The World's 25 Most Endangered Primates list, compiled at the ...Breakthrough in stem cell research
... of cells from human embryonic stem cells anywhere else in the world in Israel." By growing a human stem cell colony from a single cell, researchers are one step closer to deriving a homogenous population of cells of a particular type. "There are about 230 different cell types in the body. All these ce...Researchers find new giant amphibian fossils in Africa
...ause the animals we found are not present anywhere else in the world at that time. These animals seemed to be restricted to this one region of Africa that had one of the driest climates on the planet. Animal communities found in other parts of the world are similar to each other, but completely different ...Glaciers from Antarctic peninsula in widespread retreat, Science study says
...This is a unique glacier archive. There is nowhere else in the Antarctic with such good photos dating back to the late 1940s," said Cook, who spent many hundreds of hours wading through piles of photos, historic records and satellite images to create three cartographic-quality maps that will soon be avail...Monkeys adapt robot arm as their own
...sly doing one thing with its own arm and something else with the robotic arm," he said. "So, our hypothesis is that the adaptation of brain structures allows the expansion of capability to use an artificial appendage with no loss of function, because the animal can flip back and forth between using the tw...Engineers improve plastic's potential for use in implants by linking it to biological material
... of 12 amino acids. To make certain that something else on the outer surface of the bacteriophage virus wasn't responsible for its perceived stickiness, the researchers demonstrated that T59 by itself could attach to immobilized polypyrrole, using synthetic copies of it made at the university's Institute ...U.N. mulls the protection of Earth's forests
... say, 'This resource is mine. I don't want someone else telling me how to manage it.' Nevertheless, there are regional and global services provided by otherwise local forests, including carbon storage and life-giving oxygen." The U.N. Forum on Forests was created by the U.N. Economic and Social Council in...Bee mites suppress bee immunity, open door for viruses and bacteria
... does not lead to sudden hive collapse. Something else is involved that makes bee mites so harmful to bee colonies. The Penn State researchers report their findings in today's (May 17) online version of the Proceedings of the National Academy of Science. Yang and Cox-Foster looked at how bee mites affe...Ecosystems, economic choices and human well-being
...id the services they supply would dwarf everything else in value. The Millennium Ecosystem Assessment delivers this message loud and clear, reflecting the consensus of over 1,300 scientists that ecosystems support human life, and by harming them we harm ourselves. The sooner we realize this and behave a...Vampires beware: Scripps scientists describe molecular basis of raw garlic's pungency
...elize, slightly changing the flavor. But something else changes in the garlic when it is roasted -- its chemical makeup. Raw garlic is full of sulfurous compounds, including a chemical called alliin, which is concentrated within the body of the garlic, making up about 0.25 percent of the ma...Double triumph in stem cell quest
...e it so I can charge you, I have done it so no one else can charge me," he assured them. Verlinsky's method would have huge advantages if it really does work. Obtaining the large numbers of fresh human eggs needed for therapeutic cloning is not possible for legal reasons in many countries and is very exp...Cure for common cold will need to wiggle to work, scientists say
...de in a crowd because it always looks like someone else - it's the bug of a hundred faces." The viral shell also changes shape during the life cycle of a single rhinovirus particle. One part of the shell that seems to guide these shape changes is a small, cigar-shaped cavity within the folds of a protein ...Scientists journey to southern Africa to unravel the secret world of elephant communication
... it's what got me to think maybe there's something else going on other than acoustic communication." In 1995 she was accepted to the doctoral program in ecology at UC-Davis and began working with Professor Lynette Hart, an authority on the social behavior of large mammals. Their first goal was to prove to...A radical solution for environmental pollution
...s that catalyze these reactions work, for everyone else it could mean less pollution."...Once given 'no respect,' cells' tiny RNAS take driver's seat
...lled microRNAs, other genes they regulate, and how else they might be involved in Myc-mediated initiation of cancer," says O'Donnell, who conducted her graduate work in Dang's laboratory....