Universal flu vaccine being tested on humans
... to these frequent mutations, the virus is able to elude the antibodies that have been built up during a previous infection or vaccination. This is why we run the risk of catching the flu each year and also why a new flu vaccine must be developed each year. A universal flu vaccine that provides broad and l...Scientists identify specific enzymes that make meningitis hard to fight
...es play in the process that enablesthe bacteria to elude the body's natural defences could eventually helpscientists develop novel new treatments for meningitis and thesepticaemia it can cause. Both are extremely serious conditions with ahigh mortality rate, which take hold quickly and are difficult to tre...Other highlights in the Feb. 21 JNCI
...s in mice, but the mechanism for this continues to elude researchers. The KISS1 protein also plays a role in sexual maturation when it is secreted and then processed into smaller peptides called kisspeptins, which in turn bind to a receptor known as GPR54. Kevin Nash, Ph.D., in the laboratory of Danny R....Oxidative stress stimulates p38 MAPK-mediated tumor suppression
...induced ROS accumulation and that cancer cells may elude this protective mechanism by uncoupling ROS from p38-alpha. "Our results illustrate a mechanism used by cancer cells for the inactivation of tumor suppressor pathways and suggest that restoring the ROS-induced activation of p38 MAPK, for example, by ...Pressured by predators, lizards see rapid shift in natural selection
...ster-running -- Anolis lizards would be favored to elude capture. However, as the lizards grew ever more arboreal in habitat, the scientists projected that natural selection would begin to favor shorter limbs, which are better suited to navigating narrow branches and twigs. Their hypothesis was borne out...Tiny Tampa Bay fish key to evolution of immune system
... similar to ours that enable it to also skillfully elude attack. "This influences our therapeutic strategy because we must consider that an organism we are trying to target may have an elaborate defensive system of its own, with features that neutralize what we're trying to do to it," Ostrov said. "For ex...Celiac success: New enzyme efficiently degrades gluten in 'human stomach' environment
... disease in many ways." Currently the only way to elude the disease symptoms is by avoiding wheat, barley and rye products. "It sounds easy, but gluten especially is widespread in Western diets," Koning said. Gluten is often used as a food additive because it adds protein content inexpensively and also gi...Failure to dispose of unneeded cells during development linked to cancer
...sults in sympathetic neuronal progenitors that can elude developmental apoptosis and have a high risk of becoming cancerous later on. These results explain why NF1, c-RET, SDH, and VHL mutations are rare in somatic pheochromocytomas because mutations in these genes would no longer cause problems after the...42 biomedical scientists worldwide named HHMI international research scholars
...ma brucei, which causes African sleeping sickness, elude the host's immune response by changing their protein coatings. His research will use molecular and cell biology tools including nuclear architectural positional analysis, proteomics, and functional complementation of promoter activity. * Se...Ancient immune defense mechanism is no match for HIV-1
...ressor of RNA silencing (SRS). Tat helps HIV-1 to elude the cell's natural RNAi defense by interfering wit...present a viable target for RNAi that HIV-1 cannot elude by using the point mutation mechanism, " explains Dr. Jeang....Lupus Research Institute increases funding for innovative research
...ains enigmatic and curative treatments continue to elude us, the LRI has chosen to support investigators who bring innovative and creative ideas to the table," said LRI Novel Research Taskforce Co-Chairman Nicholas Chiorazzi, MD, Director of the North Shore-Long Island Jewish Research Institute. "This aff...A new study shows that lower doses of radiation elude a damage detection "radar" in DNA and actually kill more cancer cells than high-dose radiation. With these findings, scientists believe they can design therapy to dismantle this "radar" sensor allowing more radiation to evade detection and destroy ev...