An embryonic stem cell model for Parkinson's disease
...lleagues make the case that a model based on mouse embryonic stem cells offers a promising platform for dissect...e authors are hoping to extend their work to human embryonic stem cells, but their work is limited by the availability of such cells under the current NIH guidel...Marine Biological Laboratory summer investigator wins Nobel Prize in Chemistry
...d in regulating cell division, aids in controlling embryonic development, and helps maintain the immune system. It is implicated in a number of diseases as well, including cervical cancer caused by the human papilloma virus. Because it is involved in the body's inflammatory response to invading microbes, it ma...Embryonic stem cells correct congenital heart defect in mouse embryos
...nce describes a previously unsuspected capacity of embryonic stem cells to influence neighboring defective cell...orial Sloan-Kettering Cancer Center report that 15 embryonic stem cells injected into early embryos of mice whose hearts were genetically predisposed to develop ...'Junk' DNA may be very valuable to embryos
...y contribute to the reprogramming of the mammalian embryonic genome, a prerequisite for normal development. ...Researchers provide road map for generating B cells from stem cells
...ise to the different types of blood cells. Unlike embryonic stem cells, HSCs have already taken some steps in differentiation and are committed to producing various types of blood cells. "This is a wonderful model system," Singh said. "We know more about the differentiation of B cells and red cells than othe...Workshop on Responsible Stem Cell Research
The federal government provides funding for human embryonic stem cell research only to scientists working on approved lines of pre-existing stem cells. Privately funded researchers at many businesses and academic institutions, however, are pursuing studies on stem cells derived from donated embryos and not in...Rice engineer wins prestigious Annunzio Award
...omson, the first researcher to isolate and culture embryonic stem cells; Nobel laureate Dr. James Cobey, an active leader in the International Campaign to Ban Landmines; influential architect Michael Graves, who designed several buildings on the Rice campus; and Dr. Anthony S. Fauci, a pioneer in the study of ...Research into the sense of touch in worms wins Eppendorf/Science Prize
...vision and the generation of cell diversity in the embryonic murine cerebral cortex. She is now a postdoctoral fellow in Dr. Sally Temple's laboratory working on mechanisms regulating neural stem cell self-renewal and cell fate choices, including interactions between neural stem cells and endothelial niche cel...S1P1 essential for tumor growth and is blocked by RNA interference
... 1-phosphate receptor 1 (S1P1), is required during embryonic development to stabilize new blood vessels. Timothy Hla and colleagues, from the University of Connecticut Health Science Center, inves-tigated the importance of S1P1 in angiogenesis in tumors. The authors implanted mice with Lewis lung carcinoma cel......ystem that inactivates BMP signaling late in mouse embryonic development. Most of the joints in this mouse strain formed normally. However, the mice rapidly developed severe arthritis after birth. By 7 days old, the expression of proteins normally found in cartilage was reduced, although at this stage the kne...Leading scientists to discuss research applications for therapeutic cloning
...rsity, reported the successful harvesting of human embryonic stem cells from a cloned embryo. The cloning sympo...nclear. At this point, we don't even know if human embryonic stem cells are safe, let alone effective," said Dr. Schatten. "What's important is that research be ...Mice thrive despite massive genetic makeover
...n-base-pair mouse genome were deleted. To do this, embryonic cells were genetically engineered to contain the newly compact mouse genome. Mice were subsequently generated from these stem cells. The research team then compared the resulting mice with the abridged genome to mice with the full-length version. A...For inferring the biological tree of life, simple is better
...hips between species. When scientists compare the embryonic development among species, their conclusions all depend upon accurate knowledge of the evolutionary tree. Thornton and Kolaczkowski performed their experiments on a small supercomputer they assembled in the Thornton laboratory by linking together a c...Mouse study: 'Critical' Down syndrome region isn't
...rted each of the engineered chromosomes into mouse embryonic stem cells, creating stem cells with either three copies of DSCR or only one copy of DSCR. These stem cells were then used to create chimeras -- animals whose make-up comes partially from their original cells and partially from the inserted, engineer...Human embryonic stem cells promising for replacement of blood supply
...g how blood cells develop through the use of human embryonic stem cells. The research better defines the condi...letely compatible with the patient, such as use of embryonic stem cells to make red blood cells for platelets used in blood transfusions, or a source of new bloo...Sick kids researchers unmask the potential of stem cells found in adult skin
...n that stem cells found in adult skin retain their embryonic capability of making many types of cells. This dis...al Nature. "We think these stem cells are actually embryonic cells that go out into the skin during development and then stay in reservoirs in hair follicles," s...Ethical paradigm: Relating embryonic stem cell use to organ donation
The conflict over allowing the creation of embryonic stem cells for therapeutic purposes pits the value...gal definition, and ethical resolution, to that of embryonic cell use. Landry and Zucker detail the development of laws and practices surrounding the establishm...JCI table of contents November 1, 2004
...ation The conflict over allowing the creation of embryonic stem cells for therapeutic purposes pits the value...gal definition, and ethical resolution, to that of embryonic cell use. Landry and Zucker detail the development of laws and practices surrounding the establishm...Stem Cells: Saving Lives or Crossing Lines?
... awareness of and discuss the concerns about human embryonic stem cell research among the general public. "As ...ntroversies and ethical dilemmas surrounding human embryonic stem cell research, the United States could for the first time in modern history lose its leadersh...Growth factors confer immortality to sperm-generating stem cells
...becoming almost any other cell type and similar to embryonic stem cells. Whereas the female germ cell, the egg, stops dividing before birth, the spermatogonial stem cells continue to divide throughout life. According to Brinster, it is possible to modify the male germ line between generations by manipulating ...