Tag: "endocrine" at biology news
Study links polycystic ovary syndrome with early vascular changes of heart disease
... (PCOS), a disorder characterized by metabolic and endocrine
abnormalities, affects millions of women in the Un...g recognized as a lifelong hereditary reproductive endocrine
condition with physical and emotional consequences. Common symptoms include infertility, irregular m...
Human gland probably evolved from gills
...rom scratch when tetrapods evolved it could, as an endocrine
organ, have been placed anywhere in the body and still exert its effect.' The researchers supported their theory by carrying out experiments that show that the parathyroid glands of mice and chickens and the gills of zebrafish and dogfish contain man...
Inexpensive, mass-produced genes at core of synthetic biology advances at UH
...ting neurological diseases such as Parkinson's and endocrine
disorders such as diabetes. This technology may therefore yield profound benefits for human health and quality of life. "The technology developed by Dr. Gao and her collaborators has the potential to make research that many of us could only dream ...
Animal experiments more stressful than previously recognized
... "Research on tumor development, immune function, endocrine
and cardiovascular disorders, neoplasms, developmental defects, and psychological phenomena are particularly vulnerable to data being contaminated by animals' stress effects," notes Dr. Balcombe. Dr. Balcombe's study follows closely a recent p...
ASBMB-Amgen Award Lecture to focus on orphan nuclear receptors
... of steroid, thyroid, and retinoid hormones. These endocrine
pathways represent a cornerstone of biomedical research and have led to treatments for breast cancer, inflammatory disorders and other pathological states. In contrast, orphan receptors are a subfamily of receptors whose ligands are unknown. The exis...
A gene's fist 'kiss' sets off that affair known as puberty
...le there is a fairly good understanding of how the endocrine
system regulates the hormones involved, just how a...William F. Crowley, Jr., M.D., of the reproductive endocrine
unit at Harvard's Massachusetts General Hospital. Dr. Crowley was a senior author of a 2003 New Engl...
Effective cancer treatments follow the clock
...emperature, cardiac output, oxygen consumption and endocrine
gland secretion. In their experiments, the researchers measured the animals' body weight as an indicator of response to the anti-cancer drug. They discovered that Clock-mutant and Bmal1-knockout mice showed high sensitivity to the drug at any time it...
Ingestion of afterbirth appears to promote maternal behavior in mammals
...ture and are modified by several things, including endocrine
levels during delivery and the ingestion of substances by the mother in amniotic fluid and afterbirth," he says. "Our goal here is to determine exactly how those substances, including POEF, interact with opioid activation areas in the brain an...
The secret lives of whales
...les for 30 different pollutants. Some of these are endocrine
disruptors female hormone mimics that cause serious problems. The whole world is being feminized, says Payne. Paynes greatest hope is that in the next decade, the world will have taken heed, and instituted steps to reduce the entry of contaminants t...
Histamine, anxiety and alcoholism
...ncluding water and food intake, sleep-wake cycles, endocrine
homeostasis, locomotion, and memory and learning. In a new study, researchers have found that decreased levels of brain histamine, which are associated with a functional polymorphism of histamine N-methyltransferase (HNMT) called Thr105 allele, may ...
Neutralizing a protein linked to tumor development
...ine kinase, RET, mutations of which cause multiple endocrine
neoplasia (MEN) type 2 syndromes. Using a technique known as whole-cell SELEX (systematic evolution of ligands by exponential enrichment), a process in which large pools of oligonucleotides are enriched for molecules that can distinguish between a r...
JCI table of contents April 1, 2005
...ss and immune responses." TITLE: Ikaros integrates endocrine
and immune system development AUTHOR CONTACT: Sylvia L. Asa University Health Network, Toronto, Ontario, Canada. Phone: (416) 946-2099; Fax: (416) 946-6579; E-mail: firstname.lastname@example.org View the PDF of this article at: https://www.the-jci.org/...
Thumbnail sampler of 10 diverse physiology papers from IUPS 2005
... 348.4. Featured topic session #770: "Muscle as an endocrine
organ." Physical inactivity a well-established risk factor for cancer, but the molecular mechanisms are unclear. The researchers found that exercise-induced circulating sFlt-1 was associated with a decrease in unbound circulating VEGF. The function ...
Jeffrey Friedman, discoverer of leptin, receives Gairdner, Passano awards
...owerful effects on reproduction, metabolism, other endocrine
systems and even immune function. Mice that lack ob, and thus do not produce leptin, are massively obese, weighing as much as three times as their normal littermates. Friedman showed that after normal and ob mice are injected with synthetic leptin, t...
Water research initiatives at UW-Madison
...ovement projects Tracing mercury, antibiotics and endocrine
disruptors in water An online library for state w...ts are testing groundwater samples for evidence of endocrine
disrupting compounds (EDCs). While the effects of EDCs on humans are unclear, studies have shown tha...
Faulty body clock leads to obesity and diabetes
...emperature, cardiac output, oxygen consumption and endocrine
gland secretion. "The body clock regulates the time we go to bed, the time we get up and the time we get hungry -- these are biological principles not psychological factors," said Bass. "This internal drive is a fundamental system that is important t...
Tamoxifen-like drug suggests new ways to selectively block estrogen
...umor will determine the best SERM or SERD or other endocrine
therapy that will yield maximal benefit in the clinic." New tools such as the Advanced Photon Source at Argonne National Laboratories are making this sort of once-grandiose plan more realistic, Greene said. "We used to solve the structures of one or...
Precise timing enabled pig-to-rat transplants to cure diabetes
...cies transplantation of such primordia. Even the endocrine
part of the pancreas, where insulin is made, is di...milar to the islets of Langerhans, only individual endocrine
cells engrafted in the omentum. This is a perfect place for them to release insulin where it will do...
New research on endocrine disrupting chemicals to be presented at ENDO 2005 87th Annual meeting
...e first research to conclude there is an effect of endocrine
disrupting chemicals on humans, and the effects th...f males. The day-long forum will feature prominent endocrine
investigators presenting the most current information and recent discoveries on how hormonally-activ...
JCI table of contents June 1, 2005
...helial functions of the ANP/GC-A system from other endocrine
cardiovascular functions of the ANP/GC-A system. The endothelial functions of ANP were unknown. The authors show that the vascular endothelium is critically involved in the actions of ANP and blood volume. In an accompanying commentary, Fitz-Roy Cur...
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