New understanding of parasite cell structures may provide treatments for serious tropical diseases
...s from the mid-gut to the salivary glands where it enters the human bloodstream when the fly bites. "We found that putting these cells under stress similar to that initially encountered by the trypanosome inside the fly caused the parasites to cleave free GPIs," said Mensa-Wilmot, "and that gives us importa......y starts and marine work should cease if a dolphin enters the work area. Other innovative ideas include creating an air bubble curtain and creating a ramped warning signal to give dolphins time to leave the area before work commences. Dr David also calls for further research into the reactions of marine ma...Cracking a virus protection shield
...ghting other viral diseases. When the rabies virus enters a human cell through the membrane, the RNA molecule that carries its genes is transported into the centre of the cell. Here it redirects the cellular machinery of the host to produce many new copies of the virus that go on to infect more cells. One m...Impressive new Impact Factors for BioMed Central's open-access journals
...evelopmental biology field. BMC Structural Biology enters the Biophysics category at number eight, with an Impact Factor of 5.00. BMC Evolutionary Biology's Impact Factor of 4.45 is the 6th most highly cited journal in the evolutionary biology category. BMC Biotechnology now has an Impact Factor of 3.05, BM...The protein that makes you mad
...s the causative agent of the ailment. When PrP sc enters a living being, through feeding, it looks for the PrPc as a host and transforms it into a new PrP sc . So, the PrP c disappears and the PrP sc accumulates. Although the PrP c exists in practically all the tissues of the body, the TSEs only appear ...Figuring out function from bacteria's bewildering forms
...rescence microscopy to see where organic phosphate enters C. crescentus cells. As a gram negative bacterium, C. crescentus has two membranes -- an outer membrane and an inner membrane, with a space called the "periplasm" in between. Experiments demonstrated initial entry of organic phosphate across the ......leukaemia have a weakened immune system. If a germ enters their bloodstream via a wound, the result may be a fatal case of blood poisoning. For several years now Bonn paediatricians have been pioneering the use in Germany of medihoney in treating wounds. Medihoney bears the CE seal for medical products; it...Dengue virus reveals its circular secret
...people and kills 25,000 each year. Once a virus enters a host cell, its top priority is to copy its genetic code so that it can make more virus. Flaviviruses are so efficient at this task that they can churn out tens of thousands of copies of their genome--which is composed of ribonucleic acid, or RNA--w...... other biological processes, such as after a sperm enters an egg and how flu viruses enter cells. Zimmerberg is testing the stalk hypothesis on sea urchin eggs and the nerve cells of the Woods Hole squid....UW-Madison research part of international mercury conference
...iate surroundings. Much of the methylmercury that enters Lake Michigan from tributary rivers appears to come from watersheds with large wetlands, not heavily industrialized regions. In addition, the mercury that contaminates sediments in waters around one industrial area - the city of Green Bay, Wis. - ap...$14.6 million NIH Grant will build on macular degeneration findings
...will be essential to the project, especially as it enters any translational, or treatment-related, phase," Hageman said. The participation of patients and families in Iowa, Ireland and other sites will play a critical role in the research program. Silvestri, for example, already has identified many large...USGS at 2006 International Mercury Conference
... There may only be a small amount of mercury that enters stream water, but it's still a significant amount. So how does mercury get into stream water and how does it move once it's there? In Vermont streams, USGS studied the sources and forms of mercury; how mercury moves from watershed to streams; and h...Engineer designs system to put wastewater to work
...ence Technology, Angenent describes how wastewater enters from the bottom of a system and is continuously pumped up through a cylinder filled with granules of activated carbon. Many previous microbial experiments used closed systems with a single batch of nutrient solution, but because this system is conti...Research pinpoints West Nile virus antibody binding site
... a way that it is swallowed up by the membrane and enters the cell as an "endocytotic particle." The Purdue researchers have now developed a theory for the mechanism behind the interaction and will test it in further research, Rossmann said. Once the virus penetrates the host cell, the viral membrane fuse...Chemical compounds restore normal glucose levels and insulin action in obese mice
...pacity, the organelle starts failing, and the cell enters an emergency mode, emitting stress signals. The condition is called ER stress. Cellular inflammation, insulin resistance and diabetes result. ( http://www.hsph.harvard.edu/press/releases/press10142004.htm ). Hotamisligil's team also previously iden...Study shows how cancer drug aids anti-cancer virus
...rus, is injected directly into the tumor, where it enters only the cancer cells and kills them. The study found, however, that within hours of the injection, infection-fighting immune cells are drawn into the tumor to attack the virus, reducing the treatment's effectiveness. They also found that a chemoth...Iron critical to ocean productivity, carbon uptake
...an come from the deep or from the air, but it also enters the ocean through dust deposited by the wind. Windstorms blowing sand and dust off large deserts are a major source of iron for the world's oceans. "It's like dumping a load of Geritol or some other iron supplement into the water." Three large areas ...Researcher lights the way to better drug delivery
...ligand, folic acid, once the folate-linked complex enters the cell," Yang said. "This 'conditional drug release' is usually realized by attaching folate to the drug through a linker that falls apart inside the cell. There were several linkers in common use, but with mixed efficiency. In this study we undert...JCI table of contents: September 21, 2006
...occur when the parasite leaves the bloodstream and enters the brain. The mechanisms by which the parasites invade the brain have not been well defined. Now, in a study using human cells in culture, which appears online on September 21 in advance of publication in the October print issue of the Journal of Cl......G would work as an effective substitute because it enters cells and clogs up certain cellular enzymes. As a result, the body can't use its own glucose. Though ketogenic diets seem to work in many epilepsy patients in whom existing treatments have been unsuccessful, scientists have struggled to understand t...