New, more direct pathways from outside the cell-to-cell nuclei discovered
...tudy the kinds of external molecules that can gain entry to the nucleus through these newly defined pathways and how these materials influence the nucleic material and its processes," said Gavin....American Chemical Society's Weekly PressPac -- Aug. 1, 2007
...n exposure to water. The resultant swelling blocks entry of additional moisture, they said. Under dry conditions, the crystals shrink back to their original size and allow moisture to evaporate. The net result is a significant reduction in water permeability, that can be expected to increase the service li...New survey documents the headaches of computerized medicine
...ealth care industry as computerized provider order entry (CPOE) systems promise to improve health outcomes, reduce medical errors and increase cost efficiency, but hospitals adopting them must plan for immense workflow issues and a host of other unanticipated consequences that come with them or face poten...Can the tonsils influence oral HIV transmission?
...ssion of molecules associated with HIV binding and entry coupled with decreased innate antiviral factors may render the tonsil a potential site for oral transmission. The decreased amount of keratin and antiviral proteins in the tonsils renders this tissue more permeable to foreign invaders, thus allowing ...A new plant-bacterial symbiotic mechanism promising
...ignalling pathway Bradyrhizodium might use to gain entry to the plant and set off nodulation. The first observation was that the bacteria did not penetrate the roots of its host-plant by the hairs. It took advantage of crack zones comparable with wound areas. The set of results obtained from subsequent wo...SNM initiatives supported by inclusions in NAS Report on competitiveness of US chemistry research
...hysiologies; national impediments to the efficient entry of promising new radiopharmaceutical compounds into clinical feasibility studies and strategies to overcome them and impacts of shortages of isotopes and highly trained radiochemists on nuclear medicine research; and short- and long-term strategies t......elongate shells are adaptive in protecting against entry attacks and rounded shells are adaptive in protecting against crushing attacks. Trade-offs between force and fit have a significant, important role in both morphologies of snails and snail predators in evolution, said Konuma. ...New amfAR research grants to optimize HIV treatment
...iroc can decrease HIV disease both by blocking HIV entry into cells as well as decreasing immune activation...ork, NY $119,654 Acute HIV Infection awareness and entry into care among high risk populations: The risk of transmitting HIV to others is particularly high d...News tips from the Journal of Neuroscience
...Robo2, one branch consistently overshot the dorsal entry zone (DRZ) and prematurely grew into the spinal cord. This defect apparently arose from loss of negative or repulsive signaling by DRZ-expressed Slit acting on Robo receptors on sensory neurons. The Noise in Eye Movements Javier F. Medina and S...Mucosal-surface immune function discoveries could boost vaccine research
...hogens that use mucosal surfaces as their point of entry into the body -- viruses such as HIV, or rotavirus, the diarrhea pathogen that kills millions of children in poor countries each year," he explains. His team published their findings in the June issue of Immunity. The new research focused on a ty...Lack of sun does not explain low vitamin D in elderly who are overweight
...tamin D is sequestered in fat tissue, reducing its entry into the blood....Study of underground lakes in Antarctica could be critical, prof says
...nited Kingdom and others, have concluded that lake entry and sampling will ultimately be necessary to accomplish the ambitious research objectives, Kennicutt notes. How to do this in the best way to preserve these environments and to be least invasive is a key question that needs further discussion, he ...A new plant-bacterial symbiotic mechanism promising for crop applications
...ignalling pathway Bradyrhizodium might use to gain entry to the plant and set off nodulation. The first observation was that the bacteria did not penetrate the roots of its host-plant by the hairs. It took advantage of crack zones comparable with wound areas. The set of results obtained from subsequent wo...News tips from the Journal of Neuroscience
... axons made it over the barrier of the dorsal root entry zone, but they grew throughout the six dorsal laminae. However, the combination of NGF and Sema3A restricted SP-positive fibers to laminae I and II, similar to the normal pattern. Both groups recovered nociceptive function. 3. Mapping the Unpredic...Wellcome Trust and GlaxoSmithKline announce partnership to target drug-resistant hospital infections
... pathogen, but must first overcome the barriers to entry into the cell. The resistance of various types of bacteria to treatment is creating new challenges in the management of infection. Few new antibiotic classes have entered the market in the last 40 years. In recognition of this challenge, GSKs Infe...University of Texas researcher earns APS Bowditch award
...If sodium channels are too active, more salt gains entry to the cells, ultimately causing an increase in blood pressure. On the other hand, if the channels are not active enough, it can lead to salt wasting and hypotension, or abnormally low blood pressure. A career in research From the time he was a ...BDSI announces positive phase III clinical trial results
...nts from the efficacy study were also eligible for entry in the long-term safety study with BEMA Fentanyl, which is still ongoing. The two studies together will form the foundation of BDSIs New Drug Application (NDA) scheduled for submission during the third quarter of 2007. Prior to this submission, BDS...Jefferson researchers' discovery may change thinking on how viruses invade the brain
...ut we didnt find a difference in the initial viral entry in the central nervous system. We actually saw that the virus replicated better with the binding site than without it. LC8 is a transcription factor that helps the virus efficiently replicate in cells." The researchers were surprised by the finding...Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
...cells have cancer stem cell properties provides an entry point into further research into cancer-causing stem cells. BRCA1 regulates human mammary stem cell self-renewal and differentiation: Abstract 5700 Mutations in the well-known breast cancer susceptibility gene BRCA1 have a role in the propagat......ular membranes and act as gatekeepers to allow the entry of certain substances, like nutrients, into the cell and promote the export of other substances, like toxins, out of the cell," says Professor Igor Stagljar, Department of Medical Genetics and Department of Biochemistry at the University of Toronto a...