Tag: "enzyme" at biology news
Researchers extend mouse lifespan by protecting against free radicals
...his colleagues focused their study on catalase, an enzyme
in the body that helps convert hydrogen peroxide i...on that made them produce more human catalase, the enzyme
that breaks down hydrogen peroxide. They targeted delivery of the catalase to different areas of the...
Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
...ering the ingenious mechanism used by a particular enzyme
to modify bacterial chromosome chemistry, scientis...Cell. Scientists have known for many years that an enzyme
called Dam (DNA adenine methyltransferase) plays a role in regulating gene expression in many bacter...
Scientists inhibit cancer gene
...e researchers explain that they have discovered an enzyme
that, when inhibited, appears to reduce the incidence of Ras-induced tumors in mice. They reported their findings in the May 9 - 13, 2005, issue of the journal Proceedings of the National Academy of Sciences Online Early Edition. Matthew K. Topham...
...n injected. Inside the body, a naturally occurring enzyme
interacts with the prodrug, snipping off a part of...drugs; leading scientists to suspect that a second enzyme
with a similar structure that is targeted by the Alzheimer's treatment might be involved. Weizmann I...
Brain chemical serotonin involved in early embryo patterning, Forsyth scientists find
...irst few cell divisions and then is degraded by an enzyme
(Monoamine Oxidase) which has many important functions in human neuro-medicine. Chick embryos, on the other hand, synthesize their own serotonin shortly after laying. Though details (such as the origin of the serotonin) differ, both species utilize s...
Fat's fate depends on its source
...he researchers inactivated fatty-acid synthase, an enzyme
that generates new fat from carbohydrates, in the livers of mice. When fed a diet completely lacking fat, the mice developed low blood sugar and fatty liver. Both conditions were reversed when the researchers restored fat to the animals' diets. "It i...
Newly identified enzyme group converts protein into cellular traffic signal
...e their cargoes? The researchers identified a new enzyme
group that attaches an unusual molecular tag to a ...varying length and branching patterns. Because the enzyme
complex is active only for a short window during development in mice, it took a "biochemical tour de...
Innovative coating could give medical implants a longer life
...ol but it lasts longer because it is a peptoid and enzyme
resistant. Plus, the structure of the polymer's backbone, which is based on a natural peptide, should make it very biocompatible and prevent evoking an immune response in the body." The researchers tested their coating on titanium dioxide (a materi...
MMP inhibitors may offer hope in the fight against prostate cancer-induced bone disease
...gulated, including the gene for MMP-7. MMP-7 is an enzyme
that regulates communication between the tumor and surrounding normal tissue by processing cytokines and growth factors to active forms, and which has been shown to be involved in the invasion and spread of several cancers. Cells called osteoclasts a...
Dietary supplement a potential treatment for Canavan disease
...D has been linked to mutations in the gene for the enzyme
aspartoacylase (ASPA), which leads to the buildup of N-acetylaspartic acid (NAA) in the brain. Significant accumulation of NAA in the brain is closely associated with CD, which is characterized by the destruction of myelin. This causes the white mat...
Marine sponge yields nanoscale secrets
...or this protein, they found that the protein is an enzyme
that acts as a catalyst a surprising discovery. N... that discovery, the researchers learned that this enzyme
actively promotes the formation of the glass while simultaneously serving as a template to guide the...
Study is first to show side-stream smoking is as damaging to IVF success as being a smoker
...le and their production of the oestrogen-producing enzyme
aromatase, but that the lethal results were not apparent until later in embryonic development. However, this was still only speculation. It was clear, the researchers concluded, that it is essential to study the effects of cigarette smoke on the fema...
Natural relaxant protects against asthma, may yield new therapy
...rway responses of normal mice and those lacking an enzyme
called GSNO reductase, which breaks down SNOs. The Duke researchers earlier showed that the enzyme
governs GSNO levels in many tissues, including the lung. Normal mice prone to asthma exhibit increa...
Dartmouth Medical School researchers identify enzymatic activity of neurological disease gene
...outh Medical School researchers have identified an enzyme
activity that is inactivated in all reported mutan...n as having a protein domain related to "Hint," an enzyme
they previously characterized. A large number of proteins function by modifying the structures of o...
Genetic variation alters response to common anti-clotting drug
...know that variations in a gene encoding the CYP2C9 enzyme
that metabolizes warfarin account for about 10 percent of the difference in people's responses to the drug, but tests for these genetic variations are not routinely performed. Rettie and his colleague Mark J. Rieder, Ph.D., an assistant professor...
Lactose intolerance linked to ancestral environment
...and African descent -- stop producing lactase, the enzyme
required to digest milk, as they mature. People of...however, tend to retain the ability to produce the enzyme
and drink milk throughout life. Sherman and former Cornell undergraduate student Gabrielle Bloom '03...
Scientists use gene transfer technology and common virus to block neuropathic pain
...vector remains in the dorsal root ganglion, but an enzyme
expressed by the GAD gene moves to nerve terminals in the spinal cord where it triggers production of a powerful neurotransmitter called GABA. "GABA is the main inhibitory neurotransmitter in the nervous system," Fink says. "It's like a hall monitor...
A few 30 second sprints as beneficial as hour long jog
...wed a significant increase in citrate synthase, an enzyme
that is indicative of the tissue's ability to utilize oxygen. "Sprint training may offer an option for individuals who cite "lack of time" as a major impediment to fitness and conditioning," said Gibala. "This type of training is very demanding...
Infection-fighting strategy backfires in cystic fibrosis
...al treatment." The researchers also found that an enzyme
known as DNase, which breaks apart strands of DNA, inhibits the development of biofilms. DNase is already used to break up the thick mucus that develops in the lungs of CF patients. Nick believes that it might also be useful in preventing the develop...
Novel combination overcomes drug-resistant myeloma cells
...ug, tubacin, that blocks histone deacetylase 6, an enzyme
that is critical to the aggresome's ability to function. These highly promising results, wrote the researchers, "provide the framework for clinical trials designed to enhance sensitivity and overcome resistance to bortezomib [Velcade], thereby improv...
1 2 3 4 5 6 7 8 9 10