Random gene expression may drive HIV into hiding
...e of the biggest reasons why drug therapy fails to eradicate HIV from patients. The new findings, which will be published in the July 29, 2005, issue of the journal Cell , could help scientists design new and more effective treatments to slow or halt the progression of HIV infection. HIV normally replicates r...Brain tumors may originate with neural stem cells, researchers say
...ating localized lesions would not be sufficient to eradicate tumor cells because these cells may eventually be replenished from the cell pool within the subventricular zone, the researchers said. They also determined that inactivation of both p53 and NF1 is sufficient to initiate the formation of the brain can...Antibiotics may not be enough to stop recurrent gastric lymphoma caused by Helicobacter pylori
...ent (primarily infected), 2) antibiotic therapy to eradicate bacteria, or 3) antibiotic therapy followed by re-infection. As expected, low-grade MALT lymphoma occurred in 35% of all infected animals. However, frank MALT lymphoma was more prevalent in re-infected animals (44%) than in primarily infected anim...Improving the potential of cancer vaccines
..., but such responses are too weak and transient to eradicate tumor cells." The answer lies in a group of cells called CD4+ regulatory T cells (Treg for short). These cells have the ability to suppress the body's natural immune response. If they are depleted, autoimmune diseases will result because the immune s...Report focuses on challenges to unlocking future promise of vaccines
...hington, DC October 7, 2005 Vaccines have helped eradicate and tame some of history's worst infectious diseases, but there are many more diseases out there that vaccines can help overcome. The challenges society needs to confront to unlock the future promise of vaccines against the plagues of the 21st centu...New GM mosquito sexing technique is step towards malaria control, report scientists
... there have been a number of control programmes to eradicate malaria, none of these have been entirely successful, and many have also had side effects, such as environmental damage through insecticides. This advance could one day make a major impact on the burden of ill health caused by malaria, and is another...Researchers seeking alternative to surgery for brain cancers
...be tested in mice to see if altered T cells indeed eradicate tumors and to determine optimum binding properties. Development and testing of improved T-cell receptors against various human brain-cancer cell lines would follow. The goal is a therapy with minimal side effects. Kranz's team includes co-principal i...Seafloor creatures destroyed by ice action during ice ages
...on of the ice sheets was not significant enough to eradicate all the fauna and that desolate patches were recolonised from surrounding areas. But our research confirms that the destruction was wholesale with very little surviving. Even today calving icebergs ploughing across the seafloor destroy everything in ...Restoring silenced suppressor gene kills lung-cancer cells
...ieve that using WWOX as a therapy will necessarily eradicate tumors, Fabbri says, "but we do believe that this kind of gene therapy might be useful when used in combination with chemotherapy and other therapies."...Research team develops cancer-curing T-lymphocyte-based therapy to eradicate malignant tumours
...ral, has succeeded in developing a new approach to eradicate malignant melanoma tumours in mice. The findings o... produce interferon gamma andperforine/granzyme to eradicate cancerous cells. "We are very pleased with the insights yielded to date from this research project ...Popular insecticide detected in suburban stream beds
...urb of Sacramento) contained enough pyrethroids to eradicate a small bottom-dwelling crustacean called Hyalella azteca. "These results indicate that monitoring for pyrethroids in urban and suburban streams is overdue, and the public, regulators, and the scientific community should give greater consideration to...Protein found to control tumor growth in certain breast cancers
...approaches with the potential to stabilize or even eradicate hormone-sensitive tumors."...Steps made toward overcoming biological obstacles to cell therapy for cancer
...esponses. One of the strategies being explored to eradicate established tumors is to increase the number of tumor-reactive T cells through immunization (often called a "cancer vaccine") or by growing large numbers of the patient's tumor-reactive T cells outside the body and giving them back to the patient, a ...Studies suggest new targets for tuberculosis treatments
...ent for TB," said Li. "Such a treatment might even eradicate TB microbes from infected individuals who show no signs of infection." One complicating factor is that human cells also contain proteasomes for degrading unneeded proteins. This process is essential for human cell survival. So any drug targeting the ...Worm hormone discovery may aid fight against parasitic disease
...nes work in humans findings that one day may help eradicate worm infections that afflict a third of the world'...o, he said, the same pathway could be exploited to eradicate the pests, either by keeping them perpetually in an immature state, or by coaxing them to mature bef...Protecting endangered species helps reduce poverty
... that WWF's work to save endangered wildlife helps eradicate poverty and hunger, as well as promote sustainable and fair development in rural areas. "Problems that threaten species like the destruction of habitats and natural resources often contribute to poverty," said Hemley. Conservation and sustainable m...Researchers seek answers to combat TB epidemic
... many forms, many guises. We will never be able to eradicate it from the U.S. unless we eradicate it from the world." The increasing number of multidrug-resistant strains of TB makes the disease eve...Research suggests therapy against serious side effects of smallpox vaccine
...hed and the slower adaptive immune response cannot eradicate it." Atopic dermatitis patients have high levels of signaling molecules interleukin-4 (IL-4) and interleukin-13 (IL-13) in their skin. The researchers found that IL-4 and IL-13 inhibited the production of LL-37 in atopic dermatitis patients. When the...Scientists making advances in cancer to receive international awards
...s and medical centers is helping to understand and eradicate cancer will be recognized April 1-5, 2006, by the American Association for Cancer Research (AACR) at its 97th Annual Meeting in Washington, D.C. A series of awards is given annually by the AACR the world's oldest and largest professional societyrepr......ities in Equatorial Guinea have begun a program to eradicate the endemic disease. Baron won the first ASM Public Communications Award, in 1996, for an NPR story on microbial diversity. de Guzman, The World's Southeast Asia Correspondent, covers the region from Bangkok. He examined a growing health problem for...