New biochip helps study living cells, may speed drug development
... patch-clamping, he said. Ion channels and pumps establish a difference in electrical potential across a cell's membrane, which cells use to create energy and transfer electrical signals. By quickly allowing ions in and out, they are useful for rapid cellular changes, the kind which occur in muscles, neurons...Discovery about evolution of fungi has implications for humans, says U of M researcher
... and his colleagues will continue their efforts to establish genetic relationships among fungi and to understand their roles in nature. Additional structural studies, especially of key species, are needed to determine how the organisms adapted....Temperament linked to onset of cancer and early death in female rats
...rats died of a variety of diseases, they could not establish a reason for the differences. The new study links personality specifically with cancer....In early embryos, cilia get the message across
...able to create the counterclockwise flow needed to establish left versus right. Duboraya protein, he found, is activated by frizzled-2, a member of the highly conserved Wnt signaling pathway, which orchestrates the activities of a vast number of cells during embryonic development. Explains Belmonte: "We coul...Potential new therapeutic target for asthma, allergies and cancer
...eatment," said Spiegel. "Our study is the first to establish a mechanism by which S1P can be exported out of mast cells and perhaps by cancer cells as well." In previous research, Spiegel's team found that S1P levels are significantly elevated in fluid collected from the lungs of asthmatic patients after exp...Research holds promise for herpes vaccine
...w to do its clever ICP0 trick, the virus can still establish an infection in animals, but the spread of the virus is stopped long before disease can occur. "In short, we can disarm the virus such that it is absolutely unable to cause disease, but is still remarkably potent as a vaccine," Halford said. In a ...New research to cut animal testing
...ed for animals in drug testing. Current checks to establish whether a new drug is carcinogenic can be inconclu...ive and require further testing on live animals to establish whether they are harmful or not. Dr Richard Walmsley and colleagues at the University spin-out comp......or whom it is most relevant. The HFSP Journal will establish a forum that unites and engages researchers from a wide range of backgrounds. By also publishing Commentaries and Perspectives, which provide context to the basic research articles, the HFSP Journal will encourage broader understanding and synthesis ...16 outstanding researchers receive Singapore's highest honor in science and technology
... instrumental role in convincing the government to establish the Institute of Molecular and Cell Biology (IMCB) in 1987. This proved to be a strategic milestone and critical starting point for Singapore's efforts to develop biomedical sciences. He served as Chairman on IMCB's Scientific Advisory Board from 1...Bad blood between boys and girls
...use of this increase in male births, but it cannot establish cause and effect. They conclude that "an independent confirmation of this tentative conclusion by a manipulative experiment (by experimental infection of animals) is necessary."...Have traits, will travel: Some butterflies travel farther, reproduce faster
...llows some to move away from their birth place and establish new colonies. These venturesome butterflies are st... quite a lot among females, who carry the eggs and establish new populations. For those reasons, natural selection on flight and reproductive capability acts pri......h shows that enough parasitoids can be produced to establish a founding population in an infested wheat field u... parasitic wasps, as part of an expanded effort to establish the more effective parasitoid populations in those areas. "We hope to see the populations there gr...EURYI to showcase the future of European science in Prague
...peech recognition software. "We are looking to establish a system that takes into account the characteristics of the language, of the word involved, and of context of that word both the surrounding sentence as well as the topic of conversation in order to improve predictability , " said Ernestus. Dr. Ern...Effectiveness of certain antidepressants may be influenced by gene variations of individuals
...between SSRI response and 5-HTT polymorphisms, and establish an association between NRI response and the NET G1287A polymorphism. We also found that the 5-HTTLPR s/l variation plays a role in the treatment of depression with both NRI and SSRI agents. The results of this study need to be confirmed in other popu...UCSF set to transform itself into engine of translational research
...iversities were encouraged to develop proposals to establish departments, centers or institutes, funded over five years, that would support innovative and far-reaching approaches for carrying out translational and clinical science. Seven universities, including UCSF, received funding for a full institute. The...New study aims to stop sepsis in its tracks
...d care can save patients' lives. The project may establish the first set of standard procedures to diagnose and treat sepsis in emergency departments. The National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, launched the project this month with a grant totaling...Preventive ovary removal linked to early death in younger women
...ardiovascular system," he says. "They also further establish that the effects of oestrogen are age-dependent: oestrogen may be clearly useful and protective at younger ages, but it may become less important after menopause and then have no effect or it may cause a disadvantage if given as treatment in later ye...Parasitic plants sniff out hosts
...hat in their first experiment. Finally, to firmly establish that volatile chemicals from the host plant were causing this response, the researchers used the same set-up to examine the response to extracted host volatiles, using a solvent-only sample as a control in the opposite direction. They again observed...Chemical genomic screening identifies novel therapeutic strategies for cancer
...otypes, predict their activities, and subsequently establish their mechanisms of actions with little prior knowledge about underlying mechanisms," offers Dr. Golub. ...IU, Purdue selected for major NCI biomarker tools initiative
...ram. The five grants, totaling $35.5 million, will establish a collaborative network to assess the proteomics technologies used to improve cancer research and treatment. Proteomics is the study of proteins: their structure, function and how they interact with each other. The goal of the NCI initiative is to e...