Tag: "estrogen" at biology news
Good news: As you age, leg blood vessels adapt so you can still exercise without fainting
...e conducting similar experiments in women (both on estrogen
replacement and not). They plan to study the mechanisms underlying age-related changes in vascular responsiveness to sympathetic stimulation; and to examine the importance of sympathetic outflow in regulating vascular tone and oxygen delivery to exe...
Estrogen protects male rats from aortic aneurysms
... "Earlier studies have demonstrated that increased estrogen
systemically inhibits the development of AAAs," Up...rch and his research team implanted a slow-release estrogen
pellet in half the male rats, while the other half went through the same implantation procedure, but...
Combination hormone therapy doubles breast density and quadruples risk of abnormal mammograms
...n, ages 50 to 79, who were participants in the WHI estrogen
plus progestin trial, which involved more than 16,...in the sub-study were randomly selected to receive estrogen
plus progestin and half received an identical-looking placebo. All received a baseline mammogram at ...
Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...discovered that hormone therapy (HT), specifically estrogen
plus progesterone therapy, increases breast densit...s association was strongest among current users of estrogen
plus progestin (vs. estrogen
only). "Recent research on hormone therapy has raised lots of questio...
High fiber intake reduces estrogen levels in Latina women, according to researchers
...dietary fiber is associated with lower circulating estrogen
levels. Because high estrogen
levels have been linked to breast cancer, this finding could provide a significant step toward preve...
Study demonstrates Cenestin reduces sleep disturbances/night sweats in post-menopausal women
...ti shows that a plant-derived synthetic conjugated estrogen
called Cenestin (synthetic conjugated estrogens, A...and sleeping for a longer period of time. "When estrogen
levels in a woman's body decrease, their difficulties with sleep increase," said Dr. Scharf, whose d...
Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis
...archers showed that "resveratrol did not act as an estrogen
or glucocorticosteroid," each of which have patien...y agents. Their mechanism of action is not via the estrogen
or glucocorticoid receptor; thus these agents might be beneficial in inflammatory diseases where glu...
Army-funded effort examines androgen's role in bone loss
...ls. Androgen testosterone is best-known type and estrogen
both contribute to adult bone mass maintenance: An...anabolic agent that stimulates bone formation, and estrogen
is thought to have a protective effect on bone by inhibiting resorption. "In osteoporosis, you...
New breast cancer study shows hormonal therapy not enough
...men with hormone-dependent breast cancer (requires estrogen
and/or progesterone to grow) may be undertreated i..."We discovered that women with very high levels of estrogen
receptor in their tumors can probably avoid chemotherapy, but those with lower or intermediate level...
The Molecular Profiling Institute named US provider of genetic breast cancer test
...h node negative with either a positive or negative estrogen
receptor status. Taken together with a patient's c...y, oncologists use several clinical factors --age, estrogen
receptor status, tumor size and grade-- to determine how a patient's tumor will behave and how best ...
Component of plastic stimulates growth of certain prostate cancer cells
...industrial chemical and nonsteroidal environmental estrogen
used in the manufacture of food cans, milk container linings, food storage containers and water supply pipes. About 2.5 billion pounds of the chemical are produced each year. In particular, the study showed that the affected class of prostate cancer ...
Genetic polymorphisms, antidepressant use may be associated with altered tamoxifen activity
...creasing importance as therapeutic alternatives to estrogen
for the treatment of hot flashes in patients with breast cancer as well as in unaffected women, in addition to their already established role in treatment of depression and other psychiatric illnesses. It is possible that testing of CYP2D6 genetic va...
EB and IUPS - Where cures of tomorrow can be seen in the science of today
... cardiovascular disease; genetic susceptibility to estrogen
carcinogenesis; and long term effects on adolescents' developing brains of nicotine, stimulants and other drugs. Other sessions focus on the effect of social structure and influences on drug actions and discuss how pharmacologists and other scientis...
Study provides insights on why some prostate cancer becomes resistant to hormone withdrawl therapy
...ecome cancer-causing genes known as oncogenes. The estrogen
and progesterone receptors--two receptors that become defective in many breast cancers--are also members of this protein family. The androgen receptor is a protein produced by prostate cells that binds to androgens, a family of chemically related hor...
Increased risk of osteoporosis associated with gene that one in five people have
... women the variant gene speeds up the breakdown of estrogen
and is associated with low density in the bones of...detoxifies foreign substances and also breaks down estrogen
as a normal part of maintaining proper estrogen
balance. Within the general population, several vari...
Controlling protein diversity
... have shown in previous studies that hormones like estrogen
and progesterone can change the amounts of proteins made by their target genes. When hormone binds to receptors inside the cells, they are activated to seek out target genes. They then recruit the coactivators in this case CAPER and CAPER. These coa...
Research focusing on why estrogenic hormones produce differing results
... right now for women to make a choice about taking estrogen
or other estrogen-like compounds, and, I think, it...o the argument that the long-held model for how an estrogen
receptor binds to DNA and, in turn, regulates gene transcription is need of retooling. Nardulli's te...
Findings suggests that blocking estrogen may be crucial to lung cancer survival
... may rest on their ability to hinder the action of estrogen
in lung cancer cells, according to two studies pub...n current knowledge about the relationship between estrogen
and lung cancer growth and suggest that blocking estrogen
may be vitally important to improving surv...
Signaling protein builds bigger, better bones in mice
...otected from the usual loss of bone density due to estrogen
deficiency," MacDougald adds. To confirm that Wnt10b was the key to increased bone formation, Bennett and Hankenson scanned bones from a strain of laboratory mice that didn't have a gene for Wnt10b. Lacking the ability to produce Wnt10b protein in bo...
What are little boys made of?
...ts on mice, the researchers found evidence that an estrogen
receptor in the hypothalamus called ER reg...) produced by their testes. Estradiol binds to the estrogen
receptor (ER) and this acts to turn on, or turn off, other genes which sculpt the neural arc...
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