Testosterone replacement therapy: How safe for aging men?
...f aging male SHR promotes renal injury and thereby exacerbates hypertension. The results also show that removal of endogenous androgens later in life (eight months) prevents the development of hypertensive renal injury without altering existing hypertension levels. The Big Picture The study is part of the re...Females more prone to brain damage from alcohol abuse
...ude the possibility that the male hormone androgen exacerbates cell death in males. "What we're looking at now is the involvement of testosterone in mediating the cell death in females," Wiren said. "Not just in chronic conditions, but in acute (alcohol consumption) situations, testosterone levels drop in male...Eat fish -- especially if you drink high levels of alcohol
...akes of n-3 fats, one type of EFA. This low intake exacerbates the already very low EFA levels. Essential fatty acids (EFAs) are just that; an "essential" part of the total fat intake necessary for a healthy human diet. Most EFAs come from plants, but some are animal-sourced. A new study has found that men w...JCI table of contents -- June 1, 2007
...I (HCII), which is capable of inhibiting thrombin, exacerbates the formation of arterial lesions following arterial injury or in response to abnormally elevated levels of lipids in the blood in mice. They suggest that this possibly occurs through excessive thrombin signaling through protease-activated receptors....New technologies coming too fast for Indian farmers
... seed technologies." 'De-skilling' While Bt seed exacerbates the problem by creating yet another option, the farming troubles predate its introduction. In the late 1990s, there was an epidemic of farmer suicide in the Warangal District. Many farmers are deeply in debt and have been for generations. Stone's st...Human's ecological footprint in 2015 and Amazonia revealed
... of stressors. They found that increased affluence exacerbates environmental impacts and, when combined with population growth, will substantially increase the human footprint on the planet. Researchers projected 20 nations that will have the largest ecological footprints in 2015, with the United States, China...USC groups present at Neuroscience 2006
...that are degenerating, it's not great. It actually exacerbates the degenerative process." Brinton added that HRT, when started early, appears to lower the risk of many other degenerative diseases. "It's not that you don't age," she said. "You just age better." To exploit estrogen's apparent protective mech...Researches discover gene critical for protection against septic-shock-induced death
... dysregulation in the body's inflammatory response exacerbates sepsis, the research team began looking into the genetic factors that might contribute to this syndrome. In 2002, Biswal and his colleagues discovered that Nrf2 acts as a primary regulator of most of the cellular antioxidant pathways and detoxifying ...Gene mutation found that increases severity of multisystem syndrome
...1203 protein's exact role in cells. "Somehow, this exacerbates the effects of mutations in the BBS genes." Katsanis says that he suspects the human genome contains thousands of variants with similarly subtle effects that contribute to complex genetic diseases like obesity, diabetes and hypertension....New approach to ensure challenges to data access and management don't slow scientific progress
...l to the modern scientific enterprise, the more it exacerbates inequities between scientists in rich and poor nations." Balstad and her colleagues on the PAA panel believe ICSU, with its international and multidisciplinary membership, "should assume a leadership role in identifying and addressing critical policy...Discovery links blood cell defect to common lung disorder, leads to novel treatment
...an create a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung, Howard Hughes Medical Institute researchers at Duke University Medical Center have found. What's more, the team demonstrated through studies in people and animals that inhalation of a 'souped u...Young athletes ignore skin cancer risk
...etes are also in double jeopardy, because sweating exacerbates their risk, Dr. Adams said. Perspiration on the skin lowers what's called the minimal erythema dose, the lowest UV exposure needed to turn the skin barely pink. "You've already set yourself up for trouble by not using sunscreen," Dr. Adams said, "an...Researchers discover gene that determines asthma susceptibility by regulating inflammation
... Suspecting that a defect in antioxidant response exacerbates asthma severity, the team of researchers began looking into the genetic factors that might contribute to this deficiency. In 2002, Biswal's lab discovered Nrf2 acts as a master regulator of the majority of antioxidant pathways and detoxifying enzymes...Cigarette smoke exacerbates alcohol's effects on defense against Streptococcus pneumoniae
...umoniae toward the lungs, and that smoke exposure exacerbates alcohol's effects. Streptococcus pneumoniae is...umoniae toward the lungs, and that smoke exposure exacerbates the alcohol-induced increase in bacterial penetration. "All of the infections caused by S. pneumon......hey are often kept close together in the pens only exacerbates this problem....Removing prions that cause mad cow in humans from blood
...posure to the infected prion and onset of symptoms exacerbates the challenge of determining the size of a second wave or epidemic. This asymptomatic characteristic poses the key question: How many dormant carriers of vCJD are out there who are at risk of developing clinical disease and who also may be blood don......obinstabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia AUTHOR CONTACT:Mitchell J. Weiss The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. Phone: 215-590-0565; Fax: 215-590-4834; E-mail: weissmi@email.chop.edu . Vi...