Research team develops nonhuman primate model of smallpox infection
...cle in the same journal, Rubins and her colleagues examined the host gene expression patterns of hemorrhagic smallpox in these animals. Specifically, they documented fluctuations in cellular proliferation, interferon, and viral modulation of the immune response. A better understanding of the disease process t...The PSA bounce Does it have clinical significance?
... radiation in the U.S., radiation oncologists have examined the "PSA bounce" phenomenon and determined that it is not an indicator that men will die of prostate cancer any sooner than those men who do not experience a bounce. That is the result of a multi-institutional analysis presented today at the 46th An...Society for Psychophysiology Research
...thinking processes across the lifespan. This study examined the relationship between age and physical fitness on attention and memory processes indexed by a measure of brain waves and reaction time. Results showed that brain waves reflecting attention were greater for physically fit compared to sedentary chi...Study in Royal Society journals presents evidence for inherited factors in homosexuality
...raits can also incur increased predation risk. We examined the trade-off between sexual selection and natural...cular importance for the health of populations. We examined the level of diversity at three MHC class II loci in the wolf population of Scandinavia, a populatio...Highlights of American Anthropological Assoc. meeting
...ay Re-imagining the "Urban": San Francisco is examined as a case study of how traditional concepts of urban versus suburban have changed. (Noon1.45 p.m.). Anthropological Approaches to Central Asia and the Middle East: Scholars working on both sides of the Atlantic discuss new approaches to replac...Study using robotic microscope shows how mutant Huntington's protein affects neurons
...mained constant over time. The researchers also examined the level of mutant huntingtin protein spread throughout the neurons, outside of inclusion bodies. They found that neurons with larger amounts of mutant huntingtin spread throughout the cell died more rapidly than cells with less of this protein. Th...INEEL uses extremophile bacteria to ease bleaching's environmental cost
...uld snuff out most living creatures. But when she examined the bacteria, Thompson quickly recognized its potential. "We purified the enzyme, and it was robust, hardy, and stable," she says. In fact, the T. brockianus enzyme has been the only catalase to boast such industrial-strength properties. Potential ap...Experimental drug prevents vaginal simian HIV transmission in monkeys Science study says
...al Primate Research Center in Covington, Louisiana examined the capability of PSC-RANTES to prevent vaginal acquisition of SHIV in 30 adult female rhesus macaques, Macacca mulatto, ranging from 5 to 12 years of age. Each monkey was treated with progesterone, a hormone that thins the mucosal wall and facilitat......thin the brain." No previous studies have directly examined the role of FGFs or their receptors in psychiatric illnesses. Another growth factor, called Brain Derived Neurotrophic Factor, has been hypothesized to play a role in the effects of stress on the brain and in the mode of action of antidepressants. F...Scientists explain how morphogens work
...s, Lin and colleagues blocked cell endocytosis and examined Dpp morphogen movement. They found that inhibiting endocytosis disrupts the cell's ability to transduce Dpp signaling, but does not block Dpp movement across cells. This experiment allowed researchers to distinguish the role of endocytosis in ...Sniffing out the culprits of dust allergies
... Nicolas Winssinger at the Universit Louis Pasteur examined an extract derived from dust mites. The researchers devised and used a novel combined-library approach for this purpose--a method that enabled simultaneous identification of proteases from complex samples and isolation of protease-specific inhibitors...S1P1 essential for tumor growth and is blocked by RNA interference
...implanted mice with Lewis lung carcinoma cells and examined tissue sections for S1P1 expression. S1P1 expression was found in the blood vessels only in the areas around the implanted tumor. The researchers then developed an RNA interference technique, a method that specifically blocks S1P1 expression. They s...Normal cells in tumors may aid cancer growth
...4 tissue samples from invasive breast tumors. They examined stromal cells known as fibroblasts, the major component of the tumor stroma. Fibroblasts produce the fibrous scaffolding in tumors and normal tissues. (Stromal cells also include immune cells, fat cells and blood vessel cells.) The investigato...Hepatitis C virus linked to non-Hodgkin's lymphoma
...uthor for the research. The British Columbia study examined HCV status in 550 NHL cases and 205 population controls. The study had the strength of numbers of patients to ascertain an association between HCV and NHL, confirming the viral-cancer link suspected in studies from other areas of the world where the ...Delay in cutting the cord helps premature babies
...cold. Mercer notes that few long-term studies have examined what happens to these babies as they grow up. She is conducting a randomized controlled trial funded by the National Institutes of Health of early versus later clamping times in 74 preterm babies. In this study, the infants will be followed until t...Manipulation of epigenome turns off as many genes as it turns on
...ents." In their experiments, the researchers examined the expression of nearly 8,000 genes simultaneously in a colon cancer cell line (called HCT116). By studying the genetic "fingerprint" of a sample before and after demethylation, they could measure how the treatments affected the extent to which the ...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...up Health Cooperative's Center for Health Studies, examined the link between HT and breast density among women in a broad range of categories. Her study found: Estrogen-only therapy is associated with a small increase in breast density; however, the increase is not as large as the increase in women taking H...Large-scale forces shape local ocean life, global study shows
... photo samples at each site. Back in the lab, they examined a total of 1,500 slides and counted the species found in each frame. The project took more than 14 years to complete. It led to another key finding: Latitude also plays a big role in local species richness. At the poles, part...For inferring the biological tree of life, simple is better
...equences on a hypothetical evolutionary tree. They examined which methods for inferring historical relationships correctly recovered that tree from the simulated data. They found that a simple logical method known as maximum parsimony is far more accurate under a wide range of conditions than the state-of-the......how patients respond to albuterol. The BARGE study examined the effects of two forms of the beta-2 adrenergic receptor in patients with mild asthma. The trial paired 78 participants with matching levels of airway function but with different forms of the receptor gene. Researchers compared participants who h...