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...his enzyme in dealing with stress. The group also examined the influence of AMP-1 on other pathways that regulate lifespan in different animals, specifically the insulin like signaling pathways. Experiments revealed that in some cases, AMP-1 activity contributes to longer lives and may work in parallel with ...UT Southwestern researchers trace how virus that causes AIDS spreads following oral exposure
... surprising," Dr. Sodora said. Researchers further examined the route by which cells carried SIV throughout the bodies of infected monkeys and found that T-cells and macrophages likely played key roles in disseminating the virus. Because SIV spreads so rapidly throughout the bodies of infected monkeys, it may...Prediction of gene function in mammals
...RNA processing, as predicted by the algorithm. "We examined the extent to which [transcriptional co-expression] is effective for our data, and we show that it yields almost universally superior predictions of gene function in comparison to using information regarding simple tissue specificity or tissue restri...New drug sidesteps Gleevec resistance in human trials
...levels in a small number of volunteers. "Our study examined patients in all phases of CML, including the chron...ed for each patient based on detailed studies that examined how well the drug inhibited its target a technique that was devised by Sawyers's group for use in e...Cigarette smoke a culprit in poor healing and increased scarring
...pair and Regeneration in August. Those papers also examined the role of fibroblasts, the cells that play a major role in wound healing. Wound healing is a highly choreographed, biological drama of clotting, inflammation, cell proliferation and tissue remodeling. It features an exotic cast of cl...Stanford study links obesity to hormonal changes from lack of sleep
...on sample. During the study, the researchers examined the sleep patterns of 1,024 volunteers from the Wisconsin Sleep Cohort Study, a population-based longitudinal study of sleep disorders that began in 1989. Participants between the ages of 30 and 60 underwent nocturnal polysomnography (a test during w...Carbon sink or carbon source? Aerosols play role in shifts
...mical exchanges of the greenhouse gases. The study examined six sites across the United States in the summerti...ates to additional photosynthesis." The study then examined the effects of cloudiness on the carbon cycle. Cloudiness, which increased the amount of diffuse rad...Injectable gel could speed repair of torn cartilage
...e to ultraviolet light and cartilage formation was examined over the course of three months. The material produced progressively higher amounts of healthy new cartilage during the study period, according to the researchers. Although ultraviolet light is used in the current gelling process, the process eventua...DNA breaks and genomic instability: Broken ends stick together
...ter cells. In their study, Toczyski and colleagues examined broken chromosomes both during the cells' arrest in metaphase and after cells had overridden this arrest and attempted to segregate the broken chromosome. The researchers found that when both sister chromatids of a chromosome are cut -- a so-called d...UCSB makes important advances in studies of retinal detachment
...In these first studies, the effects of oxygen were examined under "ideal" conditions. That is, oxygen therapy at 70 percent was begun immediately after creating a retinal detachment. However, these ideal conditions would not likely be encountered in a clinical situation because it would not be possible to adm...Alcohol vulnerability linked to action of insulin
...use inebriation decreases. The scientists had also examined different regions of the fly brain to determine where the Protein Kinase had its effect. In the new research they zeroed in on a small group of neurons in the brain, specifically cells producing so-called insulin-like peptides, or DILPs. The s...Gene vaccine for Alzheimer's disease shows promising results
... of Alzheimer's disease. For years scientists have examined the possibility of using a protein-based vaccine to slow the progression of the disease in its early stages. UT Southwestern researchers have created a gene-based vaccine aimed at stimulating the immune systems of mice to potentially fight off plaque...Cigarette smoking exacerbates alcohol-induced brain damage
...ic, heavy alcohol consumption, little research has examined the independent effects of cigarette smoking or its potentially compounding effects on alcohol-induced brain damage. A study in the December issue of Alcoholism: Clinical & Experimental Research has found that cigarette smoking can both exacerbate...Alcoholism and excessive food intake may share chemical pathways in the brain
...heroin. "While many brain neurochemicals have been examined for their role in modulating neurobiological responses to alcohol, the role of neuropeptide pathways, particularly those that have been shown to be involved with feeding and body weight regulation, have largely been ignored," added Todd E. Thiele, as...JCI table of contents, December 15 2004
...lleagues from University Medical Center Rotterdam examined 829 S. aureus strains from healthy donors from t...ticularly invasive forms of disease, Melles et al. examined isolates from individuals with bacteriemia, deep-seated abscesses, or impetigo and found clear evide...Return of the Staphylococcus aureus 'superbug'
...lleagues from University Medical Center Rotterdam examined 829 S. aureus strains from healthy donors from t...ticularly invasive forms of disease, Melles et al. examined isolates from individuals with bacteriemia, deep-seated abscesses, or impetigo and found clear evide...NASA study finds tiny particles in air may influence carbon sinks
...each ecosystem on cloudy and cloud-free days. They examined carbon exchange levels for high and low levels of scattered sunlight as well as high and low levels of aerosols. Measurements were taken during afternoons in the peak growing season from June through August. Years of available data varied for each si...Solving the mechanism of Rett Syndrome
... Searching for targets The researchers examined hundreds of MeCP2 binding sequences in the brains of mice. In wild-type mouse brains they found that the MeCP2 protein binds in the vicinity of some five dozen genes, several of which reside in a cluster of imprinted genes on mouse chromosome 6 (corr...Genetic predisposition can play an important role in development of lung cancer
...ersity Hospital, Reykjavk, Iceland, and colleagues examined the contribution of genetic factors to the risk of developing lung cancer in the population of Iceland. The risks for developing lung cancer for first-, second-, and third-degree relatives of patients with lung cancer were estimated by linking recor...... behaved the same way in humans, the investigators examined human scalp tissue taken at increasing ages, and determined that the same pattern occurred. Since cell survival in general is influenced by an "anti-death" gene called Bcl2, Fisher's team analyzed mice lacking this gene. In a dramatic fashion, the m...