Healthy mix of GI tract microbes are key to preventing allergies and asthma
...l cavities of all the mice in the study. Then, she examined the mice for the presence of an allergic response in the airways and compared results between mice that received antibiotics and those that did not. "The antibiotic-treated mice showed increased airway hypersensitivity to ovalbumin compared to mice t...Evidence that human brain evolution was a special event
...n controlling brain development and function. They examined how the DNA sequences of these genes changed over ...he human lineage, far more so than the other genes examined in the study. Strikingly, most of these outlier genes are involved in controlling either the overall...University of Chicago researchers discovered that humans are a 'privileged' evolutionary lineage
...teve Dorus, both of Lahn's laboratory. Researchers examined the DNA of 214 genes involved in brain development and function in four species: humans, macaques (an Old World monkey), rats and mice. (Primates split from rodents about 80 million years ago; humans split from macaques 20 million to 25 million years...Growth of common skin cancer blocked in gene-switch mice
...of Michigan and the National Cancer Institute have examined the functions of the Hedgehog (Hh) signaling pathway in basal cell carcinoma, the most common form of cancer, and have uncovered a subset of tumor cells that are resistant to inhibition of the Hh pathway. This new finding has important implications f...Brain tumor study reveals why treatment efforts fail in genetic disorder
...disappointing. To understand why, Gutmann's team examined whether all forms of RAS are overly active in mous...ing both copies of the Nf1 gene. They specifically examined support cells in the brain called astrocytes, which often are affected by neurofibromatosis 1. Surpr...JCI table of contents, 3 January 2005
... Memorial Sloan-Kettering Cancer Center, New York, examined the potential of individual breast cancer cells to...ld and colleagues from the University of Edinburgh examined macrophage function in the injury and recovery phases of liver fibrosis in mice. They found that mac...Scientists decipher genome of fungus that can cause life-threatening infections
...mpared to other pathogenic fungi. Researchers also examined the genetic determinants of its pathogenicity by c...paper. "Although the two Cryptococcus strains we examined differ significantly in virulence, we found surprisingly little difference in their gene content." ...Research identifies promising route for treating age-related hearing loss
...y reach 70-years-old. Chen did a broad survey that examined patterns of gene expression during embryonic development of the balance organ of the inner ear. His results suggested that there might be a gene that produces a protein that acts as a permanent "brake" on hair-cell regeneration. That survey, which wa...Enzyme allows B cells to resist death, leading to leukemia
...ntributes to the development of B-CLL. The authors examined leukemia cells from 40 patients with B-CLL and compared them with lymphocytes from normal donors. They found that Lyn was markedly overexpressed in CLL cells and an unusual amount of the enzyme was found in the cell cytosol. In addition, the enzyme w...Clam embryo study shows pollutant mixture adversely affects nerve cell development
... embryos' developing neurons. Reinisch and company examined periodically recorded images to see what effect, if any, the chemicals had. They also measured the levels of proteins in the normal and treated embryos to check the visual data....Combination therapy boosts effectiveness of telomere-directed cancer cell death
...dation for Cancer Research in Tokyo and colleagues examined what happens to cancer cells when telomerase inhibition is combined with inhibition of an enzyme called tankyrase 1 that is involved in making telomeres accessible to telomerase. The researchers found that both tankyrase 1 activity and telomere short...Blood test shows promise as monitor for antiangiogenic cancer therapy
...ilan and Dr. Robert D'Amato of Harvard University, examined whether circulating levels of a class of specific blood cells that contribute to the formation of tumor vessels provide any useful information about the effectiveness of angiogenesis inhibitors. The researchers found that levels of circulating endoth...Research may speed development of new oral drugs for fertility treatments
...ecause the complex had never been crystallized and examined at the molecular level. Thus, Qing Fan set out to produce crystals of the complex to use in determining its structure using x-ray crystallography. In this widely used analytical technique, x-rays are directed through crystals of a protein to be analy...Timing is everything: First step in protein building revealed
...eleased from the ribosome complex, the researchers examined how fast the pieces of the ribosome come together, and how long it takes them to fall apart under various circumstances. Their results support the idea that two separate steps take place once the instruction's starting point is found: first a structu...Hypertension risk in African-Americans linked to genetics, Stanford study finds
...Jan. 23 online issue of Nature Genetics. The study examined people with high blood pressure, a disease that kills roughly 50,000 people nationwide each year. People with this condition are more prone to heart attacks, strokes and kidney damage. Doctors have known for many years that in the United States peopl...Report assesses health implications of perchlorate ingestion
...ittee responded by pointing out that the key study examined the effects of four dose levels in a total of 37 subjects, and that four other studies had remarkably similar results. The committee was unanimous in all other findings and recommendations. The committee emphasized that the reference dose should be ...NYU biologists find new function for pacemaker neurons
...ch as sleep disorders and jet lag. The researchers examined the role that pacemaker neurons play in helping Drosophila larvae avoid light. Drosophila is a species of fruit fly commonly used in biological research. Fruit fly larvae foraging for food avoid light, presumably to keep away from predators. Unlike a...Quantum dots research leads to new knowledge about protein binding in plants
...the molecules to germinated lily pollen grains and examined them under a confocal microscope. This is the very first time that Quantum Dots have been utilized for live imaging in plant systems. The study opens the door for the potential use of Quantum Dots in live imaging of plant cells and provides valuable...Green tea extract boosts exercise endurance 8-24%, utilizing fat as energy source
... by increasing lipid utilization, in this study we examined the effect of catechin-rich GTE intake on the endurance capacity of Balb/c mice swimming in an adjustable-current water pool. We also analyzed changes in energy metabolism, especially lipid metabolism. We demonstrated that GTE intake improved enduran...Racial groupings match genetic profiles, Stanford study finds
...ide. For each person in the study, the researchers examined 326 DNA regions that tend to vary between people. These regions are not necessarily within genes, but are simply genetic signposts on chromosomes that come in a variety of different forms at the same location. Without knowing how the participants had...