New NIST reference material for peptide analysis
...gned to improve the performance and reliability of experiments to measure the masses and concentrations of peptides in biomolecular samples. The new reference material is expected to be an important tool in the analysis of proteins, both for disease diagnosis and drug discovery. Proteomicsthe study of proteins...Departure to cold water corals and other 'hot spots'
...ry NETwork). In addition their the normal program, experiments will be carried out with the help of QUEST in order to investigate the deep-sea under natural conditions during which samples will also be taken. The investigation at the cold water corals, the mud volcano and the "garden house" underwater observ...MIT-led team uncovers malaria mechanism
...ver episodes, the researchers also performed their experiments at fever temperatures (about 41 degrees Celsius), as well as normal body temperature (37 degrees Celsius). They found that RESA has a much greater impact on deformability at fever temperatures. The research team believes that when RESA travels to t...The first issue of the HFSP Journal is now available
...damental Research in Bangalore, India who combined experiments and models to shed light onto the mechanisms by which ERKII signaling spreads long distances in apical dendrites of stimulated hippocampal pyramidal neurons. Two Articles by Erich Bornberg-Bauer at the Institute for Evolution and Biodiversity, Scho...Fragile X syndrome -- A stimulating environment restores neuronal function in mice
...t pathways in learning and memory. The researchers experiments showed that this reduction was due to abnormalities in the pore-like channels that regulate the flow of calcium into neurons. Importantly, they found that increased stimulation of neurons in the mice, which enhanced calcium signaling, could restore...Stem cells may look malignant, not act it
...en malignant tissue is grown in the laboratory for experiments that test the effects of new drugs, it's possible the results are muddied, Cogle said. Drugs, if effective, may be targeting the marrow cell mimics, not actual cancer cells. "If there are bone marrow cells in this cancerous tissue, these cells may ...Predicting catastrophic transitions
...ice the recovery rate can be determined from small experiments or by analyzing the natural variations in a time series....Cannibalism of the young allows individual fish to specialize
...w plans to do new modeling exercises and practical experiments in order to further explore the suggested hypothesis. ...Studies assess effectiveness of serotonin and nerve stimulants on irritable bowel syndromes
... microdissection and an EC derived cell line. The experiments revealed expression of several ORs in the isolated EC cells, as well as the cell line. Using digital fluorescence imaging, the team found that activation of the cells with odorants caused elevation of intracellular Ca2+, followed by serotonin releas...Parkinson's protein protects neurons from stress induced cell death
...h prevents cell death under stress conditions. The experiments indicate that mutations in the parkin gene result in an impaired activation of NF-B. "This, however, promotes an enhanced susceptibility of neurons to stress-induced cell death", says Winklhofer. "Further studies will now have to show whether thes...UF researchers awaken vision cells in blind mice
...am akin to an eye test at the doctors office. In experiments overseen by Robert B. Barlow, Ph.D., a professor of ophthalmology at State University of New York Upstate Medical University, the mice were surrounded by four computer monitors that simulated the appearance of being inside a moving drum that had vert...2007 Joint Assembly in Acapulco -- press conference schedule
...nd persisted beyond a decade. Recent climate model experiments also suggest links between prolonged aridity in those regions and climate warming - both today and in the past. All in all, the demonstrated linkages suggest that the current drought has the potential to both persist and worsen. Participants Gl...Combining NSAIDs with chemotherapy, radiation may improve cancer treatment
...ocess by which cells divide. In particular, the experiments showed that celecoxib specifically kills head and ...ioxx), showed effective anticancer activity. The experiments also indicated that celecoxib and sulindac sulfide's anticancer activity was mediated through cell c...Lipoic acid explored as anti-aging compound
... lipoic acid, a remarkable compound that in animal experiments appears to slow down the process of aging, improve blood flow, enhance immune function and perform many other functions. The findings, discussed at the "Diet and Optimum Health" conference sponsored by the Linus Pauling Institute at Oregon State Un...Executable biology -- Computer science sheds light on animal development
...zerland has been able to tease out what laboratory experiments have not how and when the crucial cross-talk between cellular signaling pathways takes place in order to determine the fates of individual cells. The novel in silico model is described in a paper appearing May 18, 2007 in the open-access journal PLo...Growing nerve cells in 3-D dramatically affects gene expression
...off. To check their work, researchers repeated the experiments but this time produced multiple copies of eight genes specifically linked to cell growth. Those experiments confirmed the differences in gene activity. Hoffman-Kim and her team deployed high-powered microsc...Scientists seek useful traits in wild cottons
...table traits," Gannaway said. "The data from these experiments should give molecular breeders more tools to work with as they look for ways to diversify, improve and expand our cotton gene pool. That will benefit global breeding stocks and lead to varieties that are more flexible and productive."...Decoding protein structures helps illuminate cause of diabetes
...ni. Without their automated method, he says, such experiments would be nearly impossible. The technique also has potential application in other human diseases that involve protein mis-folding, such as Alzheimer's and Huntington's diseases. At this time, however, he says the automation of the device itself...Researchers develop way to calculate speed of bacterial sex
... "The model gives us a new tool for designing new experiments that reflect gene transfer in the real world, including such things as transport of cells in porous media of soils and aquifers," explained Massoudieh. "It also can be used for extrapolative modeling to predict rates of gene transfer in certain cases......modENCODE initiative allows researchers to conduct experiments in the flies and works that will help validate the biological relevance of the functional elements they identify. With the help of the modENCODE Data Center at CSHL, researchers will be able to combine and compare data from worm, fly and human. N...