Tag: "failed" at biology news

Researchers find protein that makes long-term memory possible

...cess. As expected, applying current to the slices failed to bring about L-LTP, because mBDNF could not be m...g proBDNF to hippocampal sections deficient in tPA failed to bring about L-LTP. These experiments showed that both plasminogen and tPA are needed to bring ab...

An old adage about apples finds scientific backing

...onomer polyphenols, which included the flavonoids, failed to have any significant effect on biochemical markers or cancer cell growth, at concentrations ranging from 10 to 100 micrograms per milliliter. But the second class, featuring the procyanidins, performed well on both tests. First, they...

Early life stress harms mental function and immune system in later years

...ed to either of the two stressors during pregnancy failed to show this response. "This finding shows that chronic stress experienced by mother rats during pregnancy may interfere with the normal development of the signaling system known to be important for communication between the stress and immun...

Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds

...e neuropathy in diabetic rodents, but the approach failed to meet expectations in human trials. By giving NGF protein systemically, high doses are needed to reach the target sensory neurons. But given at low doses, there was no benefit, and at the site of injection, it caused pain that was not well tolerate...

Government development policies, not communities, main threat to forest conservation projects

... this approach on the basis that such schemes have failed and cannot work in the long term because local populations will always grow and pressure on natural resources will increase indefinitely. Those taking this view argue that only strict protection and exclusion of local people can prevent further envir...

Study: Inadequate physical activity worsens as teenagers become adults

...sessions of significant physical activity per week failed to do so as adults. Conversely, fewer than 1 million teens exercised enough and continued to do so as adults. Blacks who were active as teens were more likely than whites or Hispanics to remain so into young adulthood."By the time individuals reach...

Antibiotic-resistant bacteria increased after clindamycin use for common vaginal infection

.... Analysis included data for women in whom therapy failed as well as those whose infection was cured, he said. While some bacterial concentrations decreased for both groups, women treated with clindamycin experienced more frequent increases in bacterial concentrations of E. coli than those who were treated ...

New source for heart bypass replacement blood vessels: Fibrin-based TEVs

...tic materials, but smaller-diameter grafts usually failed due to thrombus or plaque formation. Various tissue-engineering approaches were developed using natural or synthetic biomaterials as scaffolds for cell growth. Biodegradable scaffolds using polyglycolic acid (PGA) have shown promise and collagen gels...

Sea change: Skeletons of ancient corals different from today's

...hallenging aspects of the project. There were many failed attempts before I was able to keep the corals alive, so that I could observe their growth and calcification in the ancient seawaters." The corals were grown under special lights called "PowerCompacts" which simulated true daylight by emitting a...

Researchers discover molecular timekeeper in bone development

...isshapen skulls and spines, and as they got older, failed to thrive. Backtracking through the bone-formation process, they discovered that the defect was in the earliest steps, where the cartilage foundation was being laid and filled with minerals. Before the foundation was compl...

UCSD discovery opens new avenues for design of anti-tumor medications

...ing HIF-1alpha in endothelial cells, blood vessels failed to grow to the tumors. Without blood vessels, the tumors were starved of oxygen and nutrients, resulting in tumors were smaller in size than in normal mice and had dead tissue at their centers. To date, most efforts to develop angiogenesis inh...

GlaxoSmithKline awards $250,000 in research grants for research on drug therapies for HIV/AIDS

...tify HIV-1 transcription inhibitors, however, have failed to produce a clinically useful drug. "For the first time, our system allows us to screen for HIV-1 Tat inhibitors with the capacity to immediately block HIV-1 expression," Dr. Kutsch said. "This capacity is considered essential for a t...

No getting around RET

...al migratory stream and swell with cells that have failed to reach their normal destination; this phenotype is seen in mice only weakly lacking GFR1 (which is thought by some to regulate NCAM-mediated cell adhesion), but not in mice lacking RET. Again, the Cis-only mice showed no discernible differences fro...

University of Texas at Austin researchers identify drug-tolerance mechanism in flies

...etically modified flies that lacked the slo gene failed to develop tolerance, while flies modified to have increased slo activity were more drug resistant than normal, providing added proof of the gene's importance for tolerance. Because the human slo gene is almost identical to the one in fruit flie...

How the brain is wired for faces

...ould to discrimination tasks on faces. This effort failed dramaticallyThese data support the domain specificity of face processing."...

JCI table of contents, December 1 2004

...owed reduced reactivity with GBS patient serum and failed to cause an anti-ganglioside antibody response in mice. The report demonstrates that specific Campylobacter jejuni genes are crucial for the induction of anti-ganglioside antibodies. This increased insight into the biosynthesis of ganglioside mimicki...

New drug sidesteps Gleevec resistance in human trials

...ymptoms of patients whose chronic myeloid leukemia failed to respond to Gleevec, which is considered the standard of treatment for the disorder. In a study to be presented today at the 46th Annual Meeting of the American Society of Hematology in San Diego, Howard Hughes Medical Institute (HHMI) researchers ...

Hudson's Bay Company fur trapping policies set stage for modern environmental struggles

...efke, a UW history doctoral student, said the firm failed as a force for conservation because it was constrained by its business strategy and the constant demand for profits. "The company tried, but the very nature of the fur trade ultimately meant its conservation efforts couldn't succeed. It had to expa...

Mutant gene linked to treatment-resistant depression

...lood Institute (NHLBI). Patients with the mutation failed to respond well to the most commonly prescribed class of antidepressant medications, which work via serotonin, suggesting that the mutation may underlie a treatment-resistant subtype of the illness. The mutant gene codes for the brain enzyme, trypt...

New painkiller was born in Utah

...pain suffered by people with cancer, AIDS, injury, failed back surgery or certain nervous system disorders. The drug is expected to be available in the United States in late January 2005. It is injected into fluid surrounding the spinal cord by external or implanted pumps. "The commercial product, Pri...

1 2 3 4 5 6 7 8 9 10

(Date:8/19/2014)... Research and Network-Level Science, , Imagine if we had ... ecosystems was responding to global changes in real time. ... coupled multiple decades of information about ecological responses to ... dozens of different ecosystem types. , In fact, ... (LTER) Network, which will soon celebrate its 35th anniversary. ...
(Date:8/19/2014)... engineers have devised a new implantable tissue scaffold coated ... a few weeks. When applied to bone injuries or ... form new bone that looks and behaves just like ... could offer a dramatic improvement over the current standard ... another part of the patient,s body a painful ...
(Date:8/19/2014)... today,s crocodiles colonised the seas during warm phases and ... Anglo-French study which establishes a link between marine crocodilian ... period of more than 140 million years. , ... Universit de Lyon, France and formerly from the University ... Nature Communications ., Today, crocodiles are ,cold-blooded, animals that ...
Breaking Biology News(10 mins):This week from AGU: Long-term ecological research, predicting cholera outbreaks 2Engineering new bone growth 2Engineering new bone growth 3Evolution of marine crocodilians constrained by ocean temperatures 2
Other Tags
peekmicrosizedveganorchidsmacrochemproceduresfollowingflowingmicroscopemudtransparencyrightsdiagnosedhealingwoundspeed