Novel combination overcomes drug-resistant myeloma cells
...ay take over enough of the job when the proteasome falters to allow the cells to survive. Therefore, the Dana-Farber researchers suggested that blocking both protein disposals at once might get around this resistance mechanism. Scientists led by Schreiber at the Broad Institute designed a drug, tubacin, that...Molecular discoveries aim at advancing early diagnosis of cancers
...tremely dense breast tissue. Mammography typically falters at detecting tumors less than 5 millimeters in size, which can be a relatively late stage of tumor development. "It could really help if a blood sample was taken for gene expression screening at the time the woman had the mammogram done," Brresen-Da...