Common gout drug shown to reduce risk from colorectal cancer
...including aspirin or other NSAID use, first-degree family history for colorectal cancer, ethnicity, sports activity and vegetable consumption. Allopurinol is thought to work by blocking the action of xanthine oxidase, the enzyme responsible for excess uric acid, the culprit in gout. This...Consuming fruits and vegetables lowers risk of developing NHL
...er day of vegetables from the broccoli and cabbage family (including cauliflower and Brussels sprouts). Lower risks were also found, although not significantly, with higher intakes of whole fruits (excluding juices), yellow/orange/red vegetables and processed tomato products such as tomato sauce and tom...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
... Index (BMI), race, age at first menstruation, and family history of breast cancer do not appear to affect the link between breast density and hormone therapy use. Use of HT appears to eliminate the known protective effects against breast density that certain characteristics have--namely, older age, havin......t. Risk factors for osteoarthritis include age and family history. If we could understand the molecular mec...nt cartilage found in joints. Several members of a family of secreted proteins known as bone morphogenetic proteins (BMPs) are expressed in these stripes of c...New DNA repair enzyme makes mistakes to save lives of cells
...ause of its protein structure it belonged to the A family of polymerases, which are known for filling gaps d...hat POL-Q's behavior is more consistent with the Y family of polymerases that bypass damage. Indeed, comparisons of its protein sequence to other polymerases ...Mitochondrial mutation linked to blood pressure and cholesterol problems
...n four generations of an affected family. Although family members with each disorder hypertension, hypercholesterolemia and hypermagnesemia have the same mitochondrial mutation, the presence of the mutation does not produce all of the symptoms in each individual. While this study focuses on a rare mut...Study is looking at ways to help stroke survivors regain lost motor skills
...ay be interested in participating in the trial and family and friends interested in more information can contact 888-546-9779. Participants undergo magnetic resonance imaging (MRI) to identify the area of the brain where arm function is affected. Participants randomized to receive the investigational dev...Single genetic defect links many risk factors for heart disease and stroke
...stood out was that she said that a number of other family members also had low magnesium," said Lifton. "Tha...latives had the same problem. Further study of the family revealed a high frequency of high blood pressure and cholesterol. "That's when the real saga began,...Researchers discover gene mutations for Parkinson's disease
...on's disease cases in addition to those who have a family history of the disease. About 50,000 Americans are diagnosed with Parkinson's disease each year. The disease occurs when certain nerve cells die or become impaired and can no longer produce dopamine. Without it, individuals can develop tremor or trem...Insects implicated in the evolution of new human infectious diseases
...lls insects with the help of nematode worms. This family of bacteria are known as Photorhabdus (glowing rods) because they are the only terrestrial bioluminescent bacteria. The bodies of insects killed by Photorhabdus luminescens infection are left luminous. Genome studies have found close similarities be...Children's Hospital Boston geneticist awarded for research on muscular dystrophy
...s of work on the genetics of muscular dystrophy, a family of hereditary muscle-destroying disorders marked by progressive muscle weakness and degeneration. The ASHG's prestigious Allan Award recognizes substantial and far-reaching contributions to human genetics carried out over a sustained period of scient...Safer medical implants, more comfortable fabrics among research items at Rochester meeting
...on and structural elucidation of the calicheamicin family of enedynes, including calicheaminicin, the anti-tumor antibiotic. Jay Kunzler and Yu-Chin Lai ACS Industrial Innovation Award for the invention of Softlens 66 th contact lens material at Bausch & Lomb, Inc., in Rochester. Jamie Cucin...Academics work to help stressed-out cats
...moving house or the arrival of a new member of the family can lead to bladder problems in some cats, say the animal specialists. But the biggest stressor of all for a cat is when it doesn't get along with other cats in the house, studies have shown. Cat health professionals at the University's Hospital for ...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...les that would attach to a molecule called FKBP, a family of chaperone proteins found naturally at high concentrations in the cell. Gestwicki attached the other end of the linker to a molecule called Congo red, which is known to selectively bind to A peptide. In test-tube studies, they found that their Troj...'Broken' gene reveals evolution of salt retention and possible ties to hypertension
.... They focused on a gene called CYP3A5, part of a family known as cytochrome P450 genes, which help the body break down and eliminate a wide range of compounds, including many drugs and salt. In the kidney, CYP3A5 acts to retain salt. One version of this gene, however, a mutation known as "CYP3A5 *3," pr...Plentiful fossils of dinosaur contemporary allow population study
...reptiles. As a contribution to efforts to create a family tree for all protosaurs, a Virginia Tech graduate student is taking advantage of the plentiful and nearby collection of Tanytrachelos fossils to study their preservation and population dynamics. Michelle Casey of Elk River, Minn., a master's degree s...JCI table of contents November 1, 2004
...r chronic myelogenous leukemia that inhibits c-Abl family kinases, blocked TGF-binduced fibroblast morpholog...ated mice. This study provides evidence that c-Abl family members may be primary targets of profibrotic cytokine signaling and that imatinib represents a pote...Joslin Diabetes Center awards 1st Mary K. Iacocca Faculty Fellowship
...ry K. Iacocca. Over the past 20 years, the Iacocca family has contributed more than $6.5 million in grants to Joslin to fund cutting-edge research for treatments and a cure for type 1 and type 2 diabetes. To commemorate this long legacy of diabetes philanthropy, the Iacocca Foundation hosted "The Journey Sh...Loyola begins study on blood substitute in trauma patients at the scene of injury
...ed at anytime during the trial based on patient or family request. Under the study protocol, treatment will begin before arrival at the hospital, either at the scene of the injury, in the ambulance or in LIFESTAR® (Loyola's helicopter paramedic unit/air ambulance), and continue during a 12-hour post-inj......s many as 20% of colorectal cancer patients have a family history of the disease, but familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer account for less than 3% of all colorectal cancer cases. Researchers have suggested that it is likely that many cases of familial colorectal canc...