Abnormal fat metabolism underlies heart problems in diabetic patients
...the membranes in heart cells, which are built from fatty molecules, are also adversely affected by the diab...'s abnormal lipid metabolism. Furthermore, because fatty molecules are part of cells' signaling mechanisms, numerous aspects of cellular physiology become al...JCI table of contents: Aug. 9, 2007
...ntrolling feeding behavior in mice. TITLE: Brain fatty acid synthase activates PPAR-alpha to maintain energy homeostasis AUTHOR CONTACT: Clay F. Semenkovich Washington University School of Medicine, St. Louis, Missouri, USA. Phone: (314)-362-4454; Fax: (314)-362-7641; E-mail: csemenko@wustl.edu . Vie...ASU researchers partner with UOP to make biofuel for military jets a reality
...s very similar to other vegetable oils in terms of fatty acid composition, the oil yield of algae is projected to be at least 100 times that of soybean per acre of land on an annual basis. ASU, UOP LLC, Honeywell Aerospace, Southwest Research Institute and Sandia National Laboratories researchers will b...American Chemical Society's Weekly PressPac -- July 25, 2007
...test is based on differences in composition of the fatty components found in farmed and wild fish. The differences originate because farmed fish usually get a diet containing lower levels of marine-derived ingredients. With tests done on 10 wild and 10 farmed sea bass, the researchers cite the need to veri...Research shows NPD1 protects a key component of vision
...cursor is DHA (docosahexaenoic acid), an essential fatty acid (must be provided by the diet) of the omega-3 fatty acid family enriched in RPE cells in the retina and brain. DHA is a target of oxidative stress in pa...First new multiple sclerosis gene found in 30 years
...s a disease that is caused by the breakdown of the fatty sheath surrounding axons, the long spindly portions of nerve cells that carry messages from one cell to another. This sheath, known as myelin, acts much like the plastic coating insulating an electrical cord. For reasons that are not well understoo...UCLA study links air pollution to clogged arteries
...teraction between diesel exhaust particles and the fatty acids found in low-density lipoprotein (LDL) chole...ted in chemicals containing free radicals, and the fatty acids in LDL cholesterol generate free radicals during metabolism in the cells, said first author Ke...Eat fish -- especially if you drink high levels of alcohol
Essential fatty acids (EFAs) are a necessary part of an individual...bates the already very low EFA levels. Essential fatty acids (EFAs) are just that; an "essential" part of the total fat intake necessary for a healthy huma...Exercise, exercise, rest, repeat -- how a break can help your workout
...eated trial also had a pronounced increase in free fatty acids and glycerol (chemical compounds that are re...gle trial, but this result may be because the free fatty acids concentration was already high before the recovery period. Conclusions The American Coll...Metabolic syndrome -- don't blame the belly fat
...for understanding the pathogenesis of nonalcoholic fatty liver disease, one of the most prevalent liver diseases in both adults and children Shulman said. The good news, according to Shulman, is that insulin resistance in skeletal muscle can be countered through a simple intervention: exercise....Omega-3 fatty acids protect eyes against retinopathy, study finds
Omega-3 polyunsaturated fatty acids protect against the development and progress... explores the potential benefit of dietary omega-3 fatty acids in protecting against the development and progression of retinal disease. The study gives us a...JCI table of contents: June 21, 2007
Editor's Pick:A diet rich in omega-3 fatty acids may lower prostate cancer genetic risk A diet rich in omega-3 polyunsaturated fatty acids found in certain fish or fish oil, nuts, seeds, and vegetable oils may help lower prostate can...Potent possibilities for parasite attack
...arget is the CFAS gene that codes for cyclopropane fatty acid synthase, an enzyme that may be involved in producing components of the cell membrane. CFAS is present in the genomes of L. braziliensis and L. infantum, but is absent from the human genome. The parasite genes are thought to have been acquired f...JCI table of contents: June 14, 2007
...lipid storage diseases in which harmful amounts of fatty substances, such as cholesterol, build up in the spleen, liver, lungs, bone marrow, and brain, causing loss of muscle coordination and brain degeneration. The cholesterol-lowering drug Ezetimibe decreases cholesterol absorption in the intestine by ta...Can a Mediterranean diet help prevent colon cancer?
...r of monounsaturated fats from olive oil, nuts and fatty plant-based foods such as olives. Mediterranean di...tables. Researchers believe changes in dietary fatty acids from the higher monounsaturated fat intake with a Mediterranean diet will decrease the levels ...High cholesterol diets modify gene expression in atherosclerosis
...es to discover the origin of atheromatous plaques fatty deposits gradually and irregularly formed in the m...h oil (rich in omega-3 and omega-6 polyunsaturated fatty acids) for another ten days. ...JCI table of contents -- June 1, 2007
...a protein hormone excreted into the bloodstream by fatty tissue and it plays a role in the suppression of inflammation-associated metabolic disorders that may result in type 2 diabetes, obesity, and atherosclerosis. In the June 1 issue of the Journal of Clinical Investigation, Rosario Scalia and colleagues...ACS News Service Weekly PressPac -- May 23, 2007
...betic mice lose large amounts of cardiolipin (CL), fatty materials essential for the heart's production of ... The changes happen before the appearance of toxic fatty materials regarded as a hallmark of diabetic cardiomyopathy and might be used as very sensitive biom...JCI table of contents: May 24, 2007
...mal diet, as well as impaired insulin signaling in fatty tissue, liver, and muscle. The authors went on to show that insulin resistance was even further impaired in these animals when they were fed a high-fat diet and the animals were only partially responsive to treatment with TZDs. The study reveals the ...New study indicates that people may need more dietary choline than previously thought
...en and 44 percent of premenopausal women developed fatty liver or muscle damage. Six men (23 percent) developed these signs while consuming the initial 550 mg of daily choline, even though 550 mg is the current AI for men. Nineteen percent of the subjects required as high as 825 mg of daily choline to ...