Rockefeller researchers show evidence of asymmetric cell division in mammalian skin
...ntiate and produce protective proteins before they finally die and are sloughed off. "The epidermis creates a Saran Wrap seal for our body surface, keeping fluids in and harmful bacteria out," says Fuchs, who is the Rebecca C. Lancefield Professor and head of the Laboratory of Mammalian Cell Biology at Rocke...Long sought-after flowering signal found
...Tokyo, Japan, because they tell us that spring has finally arrived. As we all know, most plants make flowers only at certain times of the year, the spring blooms of cherry trees being but one example. Plants can use several cues from the environment to choose the season that is right for flowering. For examp...New look at DNA hints at origin of ultraviolet damage
...lso extends the hope that methods such as ours can finally determine how DNA is damaged by UV light in the first place," Kohler said. The Ohio State chemists are now testing other DNA strands. For simplicity, they first wanted to compare the behavior of single Adenine and Thymine bases with strands entirely ...A new link between stem cells and tumors
...ey begin differentiating into more specific types, finally becoming specialized cells like neurons, blood, or muscle. As they differentiate, they should stop dividing and usually become embedded in particular tissues. Some tumor cells are more like stem cells because they are identical, they divide quickly, ...Can ancient rocks yield clues about catastrophes like Hurricane Katrina?
...t freshwater run-off exceeded a certain threshold, finally to result in a rapid change to ocean anoxia. The findings, reported in Nature, the international weekly journal of science, suggest that variations in the water cycle, once they have exceeded a certain threshold, are capable of inducing major environ...UC faculty members break new ground while treading gently on the Alaskan tundra
... they received funding to do some interviewing and finally obtained a grant exclusively for interviewing 12 13 people about landscape and climate changes. "We told an NSF project manager that Chris was a philosopher and he said, 'Wow!'" said Eisner. "I've never heard an NSF official say, 'Wow'!""It's very ...Breast tumors in mice eradicated using cancer vaccine
... off and we are very excited to see the technology finally being tested in cancer patients. The dream of the cancer immunotherapist is to provide an alternative and more humane way of controlling metastatic disease than current chemotherapies." The Listeria vector is currently being prepared for a clinical t...Skull study sheds light on dinosaur diversity
... titanosaur skeleton in 2001, sauropod specialists finally can start piecing together a clearer picture of the dinosaurs' lives. One feature of the skulls is particularly intriguing. "They have elongate, sort of horse-like skulls with many openings and grooves on the outer surface of their snouts," said Wil...Protein structure key for AIDS, cell function
... struggling with this for a long time, and we have finally solved it," said Hao....Telling axons where to go and grow
... Finding that Rnf6 targets LIMK1 for degradation finally closes this circle of regulation, providing the link between actin dynamics, axonal growth and Rnf6. Importantly, the authors are able to show that changes in axon outgrowth induced by changes in levels of Rnf6 can be restored by compensatory change...Researchers show key protein necessary for normal development of red blood cells
...ive first, followed by the gamma-globin genes, and finally the adult form, beta-globin takes control following birth. Lloyd and Priyadarshi Basu, Ph.D., lead investigator at VCU, and the research team compared mice that were missing the gene for KLF2 to normal mice. They found that the KLF2-deficient mice pr...Shorter colds, milder flu may follow from newly revealed immune mechanism
...e host to ultimately clear the viral debris and so finally halt the infection. Balancing these cell death and survival pathways can determine whether the virus or the host wins the battle." Next, the researchers will look further at precisely how CCL5 prevents cell death. "In this initial study, we identifie...Latest study: Scientists say no evidence exists that therapod dinosaurs evolved into birds
... world of dinosaurs, the wishful hope that one can finally study dinosaurs at the backyard bird feeder. "It is now clear that the origin of birds is a much more complicated question than has been previously thought," Feduccia said. The UNC scientist is the author of more than 150 papers and six major books, ...UC Davis ophthalmologist to examine ancient Chilean mummy eyes
...o highlight selected cellular characteristics, and finally examining the tissues under a microscope. Preliminary findings should be available by the end of the week. Slow rehydration may postpone the findings by a day. Tests for eye diseases, such as glaucoma and macular degeneration, will be conducted, but ...Wnt signaling controls the fate of stem cells in adult brains
...became the Scientific Director of Cure Autism Now, finally pinpointed Wnt3 as the persuasive signal molecule secreted by the astrocytes. Wnt proteins form a family of highly conserved signaling molecules that play a crucial role in controlling cell expansion and lineage decisions in many types of stem cell...... more powerful computers did it become possible to finally subject the vocalizations to careful analysis. "We started recording the vocalizations to assess the factors that lead to recognition of female pheromones, but the vocalizations turned out to be much more complicated and interesting than we expected...Students discover 11,000 year old remains of Irish Elk
...sation by forest after the Ice Age, before the elk finally became extinct. The remains, which will now be scientifically dated, could add to growing evidence that giant deer were present on the island much later than palaeozoologists originally thought. The antler was found in a 'kettle hole' a hollow creat...New microscope allows scientists to track a functioning protein with atomic-level precision
...rything takes care of itself. As a result, we were finally able to resolve the minuscule, 3.4-angstrom steps taken by E. coli RNAP as it transcribes a bacterial gene." Settling the debates With these innovations in place, the research team appears to have settled some of the fundamental arguments over DNA-...Nutritional genomics identifies a potential weight-loss resistance gene
...ficantly totreatment of obese patients. But we are finally beginning to piecetogether how genetics might be used in the future, perhaps to helppredict who is likely to respond well to dietary weight-loss interventions."...'Computer-chemistry' yields new insight into a puzzle of cell division
...complicated shapes," Rudolph said. The researchers finally winnowed the possibilities to what Rudolph called "one reasonable guess" by enlisting another Duke group led by chemistry professor Weitao Yang. Yang's team, including his graduate student Jerry Parks, uses another bank of computers to calculate how ...