NIH Nanomedicine Center draws on NYU School of Medicine expertise
...lionth the size of an antto reach inside cells and fix what may be broken. As part of a new National Institutes of Health (NIH) nanomedicine grant, David Roth, M.D., Ph.D., Chairman of the Department of Pathology and the Irene Diamond Professor of Immunology, is collaborating with colleagues at academ...Regulating the nuclear architecture of the cell
... is detected, and DNA repair mechanisms move in to fix the damage." However, if these replication checkpoints are crippled in flies that also have mutations in the H3K9 methylation and RNAi pathways, Karpen says, genome aberrations accumulate "and they do die." Says Karpen, "These findings have broad...Microbe fixes nitrogen at a blistering 92 degree Celsius
... of bacteria today's plants and animals rely on to fix nitrogen. The genetic analysis reported in the Dec...estion has been, 'So why cant we find archaea that fix nitrogen at high temperatures"'" says Baross, whos been on a 20-year quest to find just such a micro...Public shares views on environmental, health and safety research needs for nanoscale materials
...aterial into the marketplace...that we have a good fix on what are the risks of that material" and if restrictions on its use are needed. He noted that prioritizing research needs will ensure that the government's investment is properly directed. Five other government representatives presented brief ov...Deep in the ocean, a clam that acts like a plant
...fixation," Eisen said. The symbiotic bacteria also fix nitrogen and produce amino acids, vitamins and other nutrients required by the clam. Studies of the deep sea have implications for studying the origins of life, Eisen said. Life on Earth may have got its start with microbes living on such chemical ...Other highlights in the Feb. 21 JNCI
...tions in DNA mismatch repair genes, the genes that fix errors that occur during DNA replication. Kristina Lagerstedt Robinson, Ph.D., of the Karolinska University Hospital in Stockholm, and her colleagues selected a group of 285 families who had been referred to the Karolinska University Hospital for ...Gene therapy shows promise as treatment for diseased limbs
...r nearly complete blockage and no other options to fix the vessels. Though 21 of 38 patients completing the trials experienced adverse effects, all negative events were attributed to their illness and not the study treatment. Because the study group was small, no effect was attributed to different dose...Other highlights from the March 21 JNCI
...type of colorectal cancer. Mismatch repair genes fix problems that arise during DNA replication when bases are incorrectly paired. Mutations in these repair genes are associated with increased risks of cancer. Stavroula Raptis and Miralem Mrkonjic, graduate students at the University of Toronto, and ...Gladstone scientists identify critical gene factor in heart development
...to ways to turn it back on or to use stem cells to fix the damaged heart. Finally, the team was able to see all of the genes that a specific microRNA affects. Each microRNA is known to control more than one gene. Dr. Srivastava's team used genomic studies to examine all of the genes that were turned on ...Protein averts cell suicide but might contribute to cancer
...n 10,000 DNA bases daily. Dedicated repair enzymes fix 80 percent or more of this damage, but the rest remains. Cells use Y-family enzymes to bypass that remaining damage when making new DNA prior to cell division, thus forcing these enzymes to copy damaged DNA. How these bypass enzymes work, howev...A 'traffic light' for neurons means 'go' for improving brain research
...f targeted genetic or pharmaceutical treatments to fix those neurons. Conceivably, direct control of neuronal activity with light could someday become a therapy in itself. A neural traffic light To selectively take control of neurons, the researchers used a virus to insert genes for producing light...Halos and horns: Fixing the 'taste' of diet soda
...ct problem? And can food scientists do anything to fix it? "If we could make diet soda taste better, it would be a big step in fighting the obesity epidemic," said Shelly Schmidt, a U of I professor of food chemistry. "Many people know they should cut calories, but they won't drink diet pop because the...Study revises dynamin's role in nerve cell function
...with dynamin 1, we'll have answers on hand to help fix that." Dynamin 1 is one of a family of enzymes involved in synaptic vesicle endocytosis -- a reverse of the process of transmission of cellular signaling chemicals, whereby molecular components of the vesicle are retrieved from the synapse surface ...Rutgers, Penn researchers capture research dollars to improve prostate cancer diagnostic methods
...ques could prove useful in treatment. A definitive fix on where cancerous tissue lies could help physicians focus radiation on that region and reduce collateral damage to neighboring tissues and organs. The researchers are also applying CAD techniques to histology, or the detailed analysis of tissue sa...New imaging method clarifies nutrient cycle
...decades biologists wondered how the organism could fix both elements, since carbon fixation associated wi...iate into heterocysts: thick-walled relatives that fix nitrogen but do not produce oxygen. Using NanoSIMS, Capone and Nealson followed nitrogen as it is ....... The other method is radioactive dating. We can fix when the ice was last in contact with the atmosphere, says Jrgen Peder Steffensen who is a researcher in the Ice and Climate group at the Niles Bohr Institute at Copenhagen University. He explains that the special isotopes, Beryllium-10 and Chlorine...Piecing together the cyanobacteria puzzle
...e of how different species of blue green algae can fix or take up atmospheric nitrogen and carbon in a single cell organism. Carbon fixation during photosynthesis produces oxygen, which inhibits nitrogen fixation. Different species of blue green algae solve the problem in different ways and scientists...Scientists take next step in understanding potential target for ovarian cancer treatment
...t suggests possibilities as to how to intervene to fix the problem. Epithelial ovarian cancer is often diagnosed at an advanced stage and accounts for about 15,000 deaths each year. Despite advances in surgical techniques and chemotherapy, overall survival rates have not improved significantly because ...FDA Nanotechnology Task Force takes positive step forward
...as it considers FDAs 2008 budget, that it needs to fix the problem of FDAs chronic underfunding. The agency urgently needs more resources to do what needs to be done on nanotechnologyand do it urgentlyalong with the many other challenges the agency faces....Isoprene emission from plants -- a volatile answer to heat stress
...s (the process by which plants use light energy to fix CO2 and produce their own food), against thermal stress. To test this hypothesis, scientists Katja Behnke and Jrg-Peter Schnitzler from the Institute for Meteorology and Climate Research of the Research Centre Karlsruhe in Garmisch-Partenkirchen in G...