Analysis reveals extent of DNA repair army
... simply knowing that BRCA1 comes in three distinct flavors gives researchers the chance to sort out the role of each in the DNA damage response and the onset of tumors. An intriguing offshoot of the findings, Elledge said, is that they provide a potential lead into the role of estrogen in breast cancer. "RAP...Queen's discovery provides new hope for people with advanced breast cancer
...e effective," he says. "In the same way that cream flavors coffee to make it taste better, the peptide enhances the effectiveness of the most widely-used breast cancer drugs today." "We greatly hope this will not only increase the positive response from patients but also will make the current drug more usef...Turmeric prevents experimental rheumatoid arthritis, bone loss, University of Arizona study shows
...na College of Medicine. Turmeric, the spice that flavors and gives its yellow color to many curries and other foods, has been used for centuries by practitioners of Ayurvedic medicine to treat inflammatory disorders. Turmeric extract containing the ingredient curcumin is marketed widely in the Western worl...In chemical genetics, a new strategy could speed drug discovery
...t remember the name. So you decide to taste all 32 flavors at the ice cream shop, one at a time, until you fi...the tasty hit, you can then test each of the three flavors in that cone individually to see which one is the key. Similarly, when a batch of proteins restored ...New groundbreaking findings in taste, smell and chemical irritation
...t to heat! One molecule - two perceptions -- Food flavors and the sweetener saccharin activate the transient receptor potential vanilloid subtype 1 (TRPV1) channel Taste trumps smell in taste-odor mixtures -- When tastes and smells are mixed, as they are in most foods, tastes may dominate the flavor. People...Toxins drove evolution of human taste sense, global study reveals
... of Human Nutrition. The ability to discern bitter flavors likely offered a survival advantage by protecting ...suggesting that more limited sensitivity to bitter flavors may have been advantageous in regions where malaria was most prevalent....TGen awarded $7.1 million to accelerate brain disease research
...of the human genome sequence to visualize how gene flavors or aberrant amounts of genes can cause human disease. The consortium centers specialize in technologies which provide information about the genes turned on or off in the diseased tissues being studied. Scientists use these microarray technologies to...Individual differences in taste perception directly related to genetic variation in taste receptors
... innate ability or inability to taste a variety of flavors and foods." Such knowledge may someday be used to help patients consume beneficial bitter-tasting compounds, such as pharmaceuticals and health-promoting bitter-tasting plants. The studies demonstrate that variations in a single bitter receptor gene ...