Tag: "formation" at biology news
New therapy for specific form of leukemia
... However, in leukemia, there is a breakdown in the formation
of white blood cells. The cells in the bone marrow... researchers have revealed a new mechanism for the formation
of active cancer genes on circular DNA fragments. The researchers are now concentrating their effor...
Amgen investigational therapy, AMG 162, increased bone mineral density with twice yearly injection
...sors. By binding to RANK Ligand, OPG prevents the formation
and activation of osteoclasts and helps keep the bone loss process in check. Amgen developed AMG 162 to mimic the effects of OPG, enhancing the body's own process to specifically inhibit the effects of RANK Ligand. Observations from pre-clinical ...
Brain circuit may permit scientists to eavesdrop on memory formation
... the hippocampus prior to training can prevent the formation
of some kinds of short-term memory. Second, if one delays the hippocampal lesion to days after training, one can observe that as the delay increases, the memory deficit decreases. These data suggest that the importance of the neocortex as a memory st...
Component of volcanic gas may have played a significant role in the origins of life on Earth
...ed on the MillerUrey experiment to demonstrate the formation
and chemistry of many of the common biological ami...vance because previous attempts to demonstrate the formation
of peptides on early Earth depended on reaction schemes that were less plausible or were not as effi...
Acoustics meeting in San Diego
...st levels of underwater sound could trigger bubble formation
in a liquid of supersaturated nitrogen. The super...) sound waves to remove impurities and prevent the formation
of defects. Gary W. Ferrell of SEZ California Research Center, SEZ America, Inc. ( firstname.lastname@example.org...
Estrogen protects male rats from aortic aneurysms
... can cause extensive tissue damage and lead to the formation
of an aneurysm." In a recent paper published in At...M experiments focused on gender differences in AAA formation
and estrogen's protective effect. This study was one of the first to include both female and male ex...
Gladstone researchers resolve key Huntington's disease mystery in Nature cover story
... the condition in 1872. The paper, "Inclusion body formation
reduces levels of mutant huntingtin and the risk of neuronal death," was co-authored by Finkbeiner and fellow GIND staff members Montserrat Arrasate and Siddhartha Mitra; Erik S. Schweitzer of the Brain Research Institute, UCLA; and Mark R. Segal of ...
Study using robotic microscope shows how mutant Huntington's protein affects neurons
...ming inclusion bodies, the researchers found. The formation
of inclusion bodies actually prolonged neurons' su...to develop ways of interfering with inclusion body formation
as potential treatments for HD and other disorders. This study suggests that finding ways to remove...
Time-lapse movies show brain cells move like a two-stroke engine
...receptors that regulate migration, and thereby the formation
of cortical areas of the brain," says Hatten....
Muscling in on a deadly cancer
...e affected development of the mouse embryo, muscle formation
in the embryo, and muscle growth that occurs after the mouse is born and satellite stem cells give rise to new muscle cells. They engineered a version of the Pax3 gene that could be converted into a Pax3-Fkhr fusion gene at any stage o...
Researchers find protein that makes long-term memory possible
...thematics, a single protein appears central to the formation
of the long-term memories needed to learn these an...sue plasminogen activator was also involved in the formation
of long-term memory. Tissue plasminogen activator, or tPA, is best known for its use in dissolving ...
Scientists explain how morphogens work
...ng signaling molecules that play a key role in the formation
of the shape and size of organs. For example, these molecules play a role in determining the bean-like shape of human kidneys. But when these molecules malfunction, they can lead to organ defects and cancers. This study provides insights into the mec...
New version of tumor-suppressor linked to progression of childhood cancer
...ic function of TrkA. The researchers conclude that formation
of TrkIII represents a tumor-promoting switch in NB. Preventing generation of TrkIII may serve to inhibit NB progression. "A potential mechanism for regulating NB progression based on alternative TrkAIII splicing rather than genetic TrkA abnormality ...
UT Southwestern researchers uncover process for sugar-induced fat formation
... show that ChREBP binds directly to the DNA of fat formation
genes, turning them on. "I think one of the most exciting findings of these studies is that a single transcription factor is directly responsible for increasing expression of multiple enzymes for making fatty acids," Dr. Miller said. "This is...
A clear view of mycobacterial infection
...ost's first moves against the mycobacterium is the formation
of a granuloma, an aggregate of cells, which consi...served that RD1 is actually required for granuloma formation
and even recruits more macrophages to granulomas. This might seem an odd strategy, as macrophages ar...
Yerkes researchers to present array of new data at Society for Neuroscience Meeting
...s demonstrate that this release triggers pair bond formation
in monogamous species. (2 pm 3 pm) Yoland Smith, PhD, associate research professor and interim director of Emory's Neuroscience Graduate Program, and his research team: showed removing a group of proteins, known as Homer, increases glutamate rece...
Trojan-horse therapy blocks buildup of Alzheimer's plaque
...ojan horse technique might be ideal to prevent the formation
of toxic amyloid aggregates to prevent Alzheimer's...rone protein could possibly interfere with amyloid formation
from the A peptide," said Crabtree. To apply the Trojan horse approach, Gestwicki constructed a seri...
Scientists closing in on nerve proteins' contributions to memory and hearing loss
...rior portion, known as Nrg-ECD, contributes to the formation
of synapses, areas where two nerve cells communicate across a small physical gap, and to other aspects of nervous system development and communication. Until recently, researchers gave little attention to Nrg-ICD, the interior portion of Nrg-1. Bu...
Is the zebra fish leading us to new therapies?
... Despite ever-growing knowledge about blood vessel formation
(angiogenesis), scientists still know little about how the new blood vessels choose their path to reach a particular organ or tissue. Discovering these mechanisms would greatly aid development of new strategies for therapeutic angiogenesis. Not only ...
Research uncovers role of Apolipoprotein E in Alzheimer's disease
...in Apolipoprotein E (ApoE) contributes to both the formation
of amyloid brain lesions and the memory loss associated with Alzheimer's disease. The research, conducted jointly by USF and the Byrd Institute, is published in the October 2004 issues of the Journal of Alzheimer's Disease and the Neurobiology of Ag...
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