Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...o the beta-amyloid fragments and prevent them from forming large clumps. As a result, these molecules are effective at reducing protein clumping at concentrations 100 times lower than other blocking agents that have been tested. Through her research grant, she hopes to further develop this approach, contribu...Research aims to identify markers for menopausal women at risk for deadly blood clot
... a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly. The hormone trials conducted thus far, focusing on proteins in blood coagulation, have not yet led to a risk profile, the...Weizmann Institute scientists discover a control mechanism for metastasis
...s two arms: One arm attaches to the protein fibers forming the skeleton, and the other anchors itself to the cell membrane. This action is what stabilizes the cells structure. The protein that increases, on the other hand, is made up of one short arm that only attaches to the anchor point on the cell membran...Preclinical study links gene to brain aneurysm formation
... occurs when a blood vessel weakens and stretches, forming a bulge in the vessel wall that can rupture and he...eabsorbing the inner layers of the vessel wall and forming new outer layers to replace them, explains Abruzzo. Although we dont fully understand the genetic...In limiting life span, study finds booming bacteria innocent
...t some of the bacteria were even banding together, forming continuous biofilms. Yet treatments that reduced the number of bacteria had no effect on life span, they found. That discovery led the researchers to conclude that, at least under optimal laboratory conditions, Drosophila can tolerate a significant n...MIT study: Maturity brings richer memories
...the MIT team reports that children rival adults in forming basic memories, but adults do better at remembering the rich, contextual details of that information. The MIT study provides new insights into how children learn that are not only theoretically important, but could also inform practical learning in e...Human knowledge is based upon directed connectivity between brain areas
... of neuronal interactions. Cooperating brain areas forming a dynamic network are not just connected, but rather each area can be engaged either in receiving or sending signals or both. Until now this has been difficult to investigate, but our analysis suggests that most areas are involved in both during acc...How cells change the pace of their steps
...ell extends its leading margin over the substratum forming a pseudopod or foot-like extension; secondly, the tip of the pseudopod develops an adhesion point that attaches to the substratum; next, the cell uses the new point of anchorage to contract; and finally, the trailing adhesion point detaches and the r...Researchers find pathway that controls cell size and division
...nutrient-poor conditions) by becoming unstable and forming what appear to be inactive aggregates. Disrupting this pathway leads to defects in chromosome segregation. A cell that is too small is unable to effectively move its DNA away from the division site and the resultant daughter cells frequently do no...Microscopic jets, diamonds unlikely on Uranus, and amazing mosquito legs
... that in turn are covered with nanoscopic ribbing, forming what the physicists have dubbed (in an apparent fit of excessive prefixing) a micronanostructure. So the next time a mosquito lands on your arm, take a moment to ponder its impressive and versatile leg adaptations -- then squish it before it sucks yo...Amoebae control cheating by keeping it in the family
...lenty, but when food is scarce they work together, forming colonies to ensure their survival. About one fifth of the individuals in a colony form a tall, thin stalk. The rest climb the stalk and clump together into a bulbous fruiting body that can be carried away to better environs by the wind or on the legs...Modern brains have an ancient core
...ells might have clustered together and specialised forming complex brain centres like the vertebrate hypothalamus. These findings revolutionise the way we see the brain, says Tessmar-Raible. So far we have always understood it as a processing unit, a bit like a computer that integrates and interprets incomin...Cord blood may preserve insulin levels in children with type 1 diabetes
...ore likely than the hypothesis that stem cells are forming insulin producing cells on their own. The idea would be to intervene and repair any early damage during the honeymoon period many patients enjoy -- the first several months after diagnosis during which insulin needs are minimal, he added. Our gro...St. Jude study shows genes play an unexpected role in their own activation
...nt genes in the brain that are key to learning and forming memories. A long-term implication of this work is that one day it might be possible to manipulate CREBs co-factors to treat disease. A drug that blocked the specific co-factors CREB needs in the liver to trigger activity of genes that make glucose ...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
...ient cell they are engulfed by its outer membrane, forming "vesicles," or tiny spheres that are drawn into the cell's interior. Once inside the cell, the bacteria dissolve the vesicle membrane and release the cargo. The method might be used to take images of diseased tissues by inserting a cargo of fluores...Study suggests other causes for childhood brain aneurysms
... occurs when a blood vessel weakens and stretches, forming a bulge in the vessel wall that can rupture and hemorrhage. Intracranial arterial aneurysmsuncommon in pediatric patientsare bulges that develop in the arteries that carry blood to the brain. In addition, Abruzzo reports that 75 percent of the pati...Genomatix expands operations in North America
...ded its operations in the North American market by forming a subsidiary company thereGenomatix Software, Inc. The new company, which will be headquartered in Ann Arbor, MI, was officially incorporated on May 14 and will provide sales, support, and marketing for the Genomatix product for all of North America....Physicist cracks women's random but always lucky choice of X chromosome
...e gene can be itself blocked by a plug of proteins forming on top of its specific location on the chromosome but they had little idea as to why this should happen randomly to one X chromosomes gene and not the other. Scientists are extremely uncomfortable with this randomness and have sought a clear scient......ing to catalyze a different reaction, could end up forming what the scientists call a complex, AB. The decidi...by. As a result, A and B will come into proximity, forming a complex. The word complex is key because it shows how simple chemical interactions, with few pla......ferent spaces. This may model the difficulties in forming distinct memories for similar but distinct places and experiences that afflicts some elderly individuals....