Tag: "fractures" at biology news
New cell transplantation technique restores insulin production in diabetics
...ss of sensation that results in severe infections, fractures
and amputations, destruction of major organ function (e.g., the kidneys) and cardiovascular disease that can result in complications such as heart attacks. Both genetic and environmental factors contribute to the disease....
Bone quality regulator identified, suggests drug target
...a possible target for preventing and treating bone fractures
associated with aging and genetic diseases. The s...n to fracture-resistance," she says. Risk of bone fractures
Susceptibility to bone fractures
and bone deterioration increases with age, often due to metabolic ...
Alcohol-induced bone disease
...d predisposes alcoholics to a greater frequency of fractures
from falls," said Chakkalakal. "A delay in fractu...ption by patients alcoholics or teetotalers with fractures
and who may want to drink during their convalescence."...
Researchers show the 'BEST' way to reduce osteoporosis risk
...in preventing osteoporosis, which often results in fractures
of the hip, spine and wrist. Adequate calcium intake and exercise throughout life help prevent bone loss, and these measures also can help the millions of Americans already diagnosed. The best treatment is prevention, and women of all ages should be...
Calcium and vitamin D supplements offer modest bone improvements, no benefits for colorectal cancer
...st benefit in preserving bone mass and prevent hip fractures
in certain groups including older women but do not prevent other types of fractures
or colorectal cancer, according to the results of a major clinical trial, part of the Women's Health...
Large European study finds gene variant is no strong risk factor for osteoporosis
...how good the COL1A1 genetic test was at predicting fractures
and to determine if it was associated with osteopo...000 people took part in GENOMOS, and the number of fractures
reported was five times greater than in all previous studies combined. The researchers conducted gen...
Investigational therapy denosumab increased bone mineral density with twice-yearly dosing
... to evaluate the effect of denosumab on preventing fractures
in men and women." In the one-year trial results, researchers also reported twice-yearly subcutaneous injections of denosumab significantly increased lumbar spine BMD from 3.0 to 6.7 percent after 12 months as compared with a decrease of 0.8 percen...
Penn researchers discover gene that creates second skeleton
... with severe bone loss from trauma, for those with fractures
that fail to heal or spinal fusions that are slow to heal, or for those with congenital malformations of the spine and limbs. We have reached a summit on our epic journey to understand FOP knowledge we desperately need to help the kids and that will...
OHSU studying drug for bone-deforming disorder
...t stature, can suffer hundreds if not thousands of fractures
in a lifetime, and are confined to a wheelchair. "...when he's not in his wheelchair - and suffer fewer fractures
than many others with the disorder. Fox had both of his legs amputated when he was 18 due to continu...
Toward a less expensive, more convenient treatment of Gaucher's disease
... a range of health problems including anemia, bone fractures
and sometimes lung and brain disorders. Kelly said researchers are now trying to identify an optimal small molecule that could be suitable for use as a chemical chaperone in clinical trials. The research team included Anu R. Sawkar, Ph.D.,...
Infant bone growth and maternal vitamin D levels during pregnancy influence future fracture risk
...ut in that their vulnerability to osteoporosis and fractures
depends on how the bones developed during pregnanc...wth during infancy can increase risk of later-life fractures
Javaid and colleagues previously demonstrated an association between poor skeletal growth in older ...
New research clarifies roles of calcium, vitamin D, and protein in bone health, fracture risk
... D, putting them at elevated risk of bone loss and fractures
(conference abstract P142SA). Experts suggest the body needs at least 50 to 80 nanamoles per liter of vitamin D in blood serum for optimal bone health. Bruyere and his colleagues analyzed vitamin D levels in 8,532 European postmenopausal women. Among...
Research identifies protein in mice that regulates bone formation
...ty and which makes people more susceptible to bone fractures
and deformities, afflicts some 10 million American...gets older, it is predicted that the number of hip fractures
may triple by 2020 unless better prevention and treatment for the disease is improved. The research...
Carnegie Mellon researchers discover new cell properties
...na. "This could make the lamina stiffer and cause fractures
in the nuclei," Islam said. The healthy lamina remains disordered and therefore less rigid. "Once we understand what causes the lamina to stiffen, we can try to reverse or stop the problem," Dahl said. "We think this stiffening mechanism happens ove...
Major new osteoporosis study to recruit people in Orkney
...ing genetic tests with which to assess the risk of fractures
occurring, and new drugs that can be used for the prevention and treatment of osteoporosis," he added. Recruitment will start this month....
Ancient raptors likely feasted on early man, study suggests
...plied by the grip of an eagle's talons. There were fractures
in the eye sockets and at the base of most of the skulls, either from beaks or talons that had punctured the bone in order to retrieve soft tissue. There were noticeable punctures and scrapes across nearly every shoulder blade in the sample. The end...
Raloxifene reduces breast cancer risk in postmenopausal women at all risk levels
...ested the ability of the drug to prevent vertebral fractures
in 7,705 postmenopausal women diagnosed with osteoporosis. The secondary endpoint of this multi-center, double-blind trial, known as MORE (Multiple Outcomes of Raloxifene Evaluation) was the drug's effect on breast cancerdevelopment; results, annou...
Clemson research cleans up with edible oil
...Murdoch said the oil is injected through hydraulic fractures
made 20 to 30 feet into the ground. When injected, the vegetable oil draws in oil-based contaminants that have leaked from pipes or tanks. If mixed with water, the contaminants separate as droplets, with small amounts dissolving into the water and ma...
Researchers discover new gene responsible for brittle bone disease
...ournal Cell. Victims may experience just a few fractures
in a lifetime or several hundred beginning before birth. The number of Americans affected is unknown, but estimates range from 20,000 to 50,000. While the study is an important early step in the search for a cure, its immediate effect may be to exone...
Hormone therapy does not improve quality of life for women
...cally significant. The hormone recipients had less fractures
and less hot flashes and night-time sweating than the comparison group, but they also had more flow. There were no differences in depression, sleep disorders, fatigue, dizziness or bloating. The EPHT trial is the first European randomised controlle...
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